
Methylergonovine Coupons & Savings Card – Discount Prices from $13.98
Generic for: Methergine
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1ML of 0.2MG/ML, Methylergonovine (1 Ampule)
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CVS
$44.08
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Walmart
$13.98
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Walgreens
$21.04
COUPON PRICEMethylergonovine savings card
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Walmart
$13.98
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Methylergonovine dosage forms
Dosage | Quantity | Price from | Per unit |
---|---|---|---|
1ML of 0.2MG/ML | 1 Ampule | $13.98 | $13.98 |
Methylergonovine Warnings
The safety information for methylergonovine, known by its brand name Methergine, is essential for ensuring its safe and effective use. Below are key warnings and contraindications you should consider. Consult your healthcare provider if you have any concerns or questions.
Breastfeeding Warning: It is advised not to breastfeed while using methylergonovine and for at least 12 hours following your last dose. The medication can be transferred to breast milk and may harm the infant. Additionally, methylergonovine may reduce milk production, so a decrease in milk supply is expected during treatment.
Heart Attack Risk: Methylergonovine can cause blood vessels to constrict, potentially reducing blood flow to the heart. This can lead to heart damage or a heart attack, especially in individuals with pre-existing heart conditions or high risk factors such as smoking, obesity, diabetes, or high cholesterol. Immediate medical attention is required if you experience symptoms like chest pain, pain radiating to the left arm or neck, or difficulty breathing.
Contraindications: This medication should not be used in the following conditions due to serious health risks:
- High blood pressure
- Preeclampsia (a condition characterized by high blood pressure during pregnancy)
- Current pregnancy
Ensure your healthcare provider is aware of all your medical conditions and any medications you are taking to avoid potential adverse interactions.
Methylergonovine Side Effects
Common side effects:
- High blood pressure
- Headaches
- Low blood pressure
- Stomach pain
- Nausea
- Vomiting
Serious side effects:
- Signs of a heart attack (chest pain or tightness, pain spreading to the left arm or neck, difficulty breathing)
- Extremely high blood pressure (seizures, severe headaches, blurry vision)
Methylergonovine Interactions
Methylergonovine, commonly prescribed to manage postpartum bleeding, can interact with various substances, potentially leading to serious health risks. It's crucial to be aware of these interactions to ensure safe and effective use of the medication.
Medications to Avoid:
CYP3A4 Inhibitors: Certain drugs can increase methylergonovine levels in the body, heightening the risk of adverse effects. Notable examples include:
- Macrolide Antibiotics: Such as Erythromycin and Clarithromycin.
- HIV Protease Inhibitors: Including Ritonavir and indinavir.
- Azole Antifungals: Like Ketoconazole and Itraconazole.
- Selective Serotonin Reuptake Inhibitors (SSRIs): Such as Fluoxetine and Fluvoxamine.
CYP3A4 Inducers: These medications may reduce methylergonovine's effectiveness by decreasing its levels:
- Antituberculosis Drugs: Such as Rifampin.
- Antiretrovirals: Like Nevirapine.
Beta-Blockers: Combining methylergonovine with beta-blockers (e.g., Propranolol, metoprolol) can enhance vasoconstriction, potentially leading to elevated blood pressure or reduced blood flow to extremities.
Anesthetics: Agents like halothane and methoxyflurane may diminish methylergonovine's effectiveness in stimulating uterine contractions.
Antianginal Drugs: Methylergonovine's vasoconstrictive properties can counteract medications like glyceryl trinitrate, used to treat chest pain.
Food and Lifestyle Considerations:
Grapefruit Products: Consuming grapefruit or its juice can elevate methylergonovine levels, increasing the likelihood of side effects. It's advisable to avoid grapefruit while on this medication.
Tobacco Use: Smoking can intensify methylergonovine's vasoconstrictive effects, raising the risk of complications. Patients are encouraged to refrain from smoking during treatment.
General Advice:
Always inform your healthcare provider about all medications, supplements, and herbal products you're currently using. This comprehensive disclosure helps prevent potential interactions and ensures the safe administration of methylergonovine. If you experience unusual symptoms or side effects, seek medical attention promptly.
What is the drug methylergonovine used for?
Methylergonovine is used to prevent or control bleeding after childbirth by helping the uterus contract. It is often administered to manage postpartum hemorrhage.
Are Methergine and oxytocin the same?
Methergine and oxytocin are not the same. They are both used in obstetrics but have different purposes and mechanisms of action. Methergine is an ergot alkaloid used to prevent or treat postpartum hemorrhage by causing uterine contractions. Oxytocin is a hormone that induces labor and controls bleeding after childbirth by stimulating uterine contractions.
What should be monitored with methylergonovine?
When a patient is taking methylergonovine, it is important to monitor blood pressure, as the medication can cause hypertension. Additionally, monitoring for signs of ergotism, such as numbness, tingling, or pain in the extremities, is advised. It is also important to observe for any adverse cardiovascular effects, such as chest pain or arrhythmias. Regular assessment of uterine tone and bleeding is necessary to ensure the medication's effectiveness in managing postpartum hemorrhage.
Can Methergine cause hypotension?
Methergine is more commonly associated with causing hypertension rather than hypotension. However, in rare cases, it may cause hypotension, especially if administered intravenously too rapidly. It is important for healthcare providers to monitor blood pressure when administering this medication.
What is the drug Methylergometrine used for?
Methylergometrine is used to prevent or control excessive bleeding following childbirth. It works by stimulating uterine contractions, which helps to reduce blood loss after delivery.