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Methylergonovine

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generic Methergine

Methylergonovine, also known as Methergine, is a medication used to manage excessive bleeding in women during or after childbirth. It is part of the ergot alkaloids class of drugs and functions by enhancing the rate and strength of uterine contractions, which helps to firm up the uterus muscles and reduce bleeding. Typically, this medication is administered three to four times daily, but it should not be used for more than one week. Common side effects may include high blood pressure, stomach pain, nausea, and vomiting. Methylergonovine is available in both generic and brand name forms. Always consult with a healthcare professional before using this medication to ensure it is safe and appropriate for your individual needs.
Our coupons are free to use. Before paying, show the pharmacist your Methylergonovine savings card to get your free discount. Use our filters below to edit the prescription box to match your needs. The Methylergonovine prices will update based on your prescription needs. Above our Methylergonovine coupons, you can change your location to see pharmacy prices and costs in other areas. We're here to help you buy Methylergonovine at the lowest price with our prescription discount card.

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1ML of 0.2MG/ML, Methylergonovine (1 Ampule)

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CVS

$37.44

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$4.17

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$13.98

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$17.61

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Methylergonovine dosage forms

The average cost for 1 Ampule of Methylergonovine (generic Methergine) at 1ML of 0.2MG/ML is $4.17 with a free coupon. This is 16.75% off the average retail price of $24.9
DosageQuantityPrice fromPer unit
1ML of 0.2MG/ML1 Ampule$4.17$4.17

Methylergonovine Warnings

The safety information for methylergonovine, known by its brand name Methergine, is essential for ensuring its safe and effective use. Below are key warnings and contraindications you should consider. Consult your healthcare provider if you have any concerns or questions.

  • Breastfeeding Warning: It is advised not to breastfeed while using methylergonovine and for at least 12 hours following your last dose. The medication can be transferred to breast milk and may harm the infant. Additionally, methylergonovine may reduce milk production, so a decrease in milk supply is expected during treatment.

  • Heart Attack Risk: Methylergonovine can cause blood vessels to constrict, potentially reducing blood flow to the heart. This can lead to heart damage or a heart attack, especially in individuals with pre-existing heart conditions or high risk factors such as smoking, obesity, diabetes, or high cholesterol. Immediate medical attention is required if you experience symptoms like chest pain, pain radiating to the left arm or neck, or difficulty breathing.

  • Contraindications: This medication should not be used in the following conditions due to serious health risks:

    • High blood pressure
    • Preeclampsia (a condition characterized by high blood pressure during pregnancy)
    • Current pregnancy

Ensure your healthcare provider is aware of all your medical conditions and any medications you are taking to avoid potential adverse interactions.

Methylergonovine Side Effects

Common side effects:

  • High blood pressure
  • Headaches
  • Low blood pressure
  • Stomach pain
  • Nausea
  • Vomiting

Serious side effects:

  • Signs of a heart attack (chest pain or tightness, pain spreading to the left arm or neck, difficulty breathing)
  • Extremely high blood pressure (seizures, severe headaches, blurry vision)

Methylergonovine Interactions

Some products that may interact with this drug include: other ergot alkaloids (such as ergotamine, dihydroergotamine), triptan migraine medications (such as eletriptan, rizatriptan, sumatriptan). Other medications can affect the removal of methylergonovine from your body, which may affect how methylergonovine works. Examples include adagrasib, cobicistat, mifepristone, nefazodone, azole antifungals (such as itraconazole, ketoconazole), macrolide antibiotics (such as erythromycin, clarithromycin), HIV protease inhibitors (such as lopinavir), ritonavir, among others.
Methylergonovine FAQs
What is the drug methylergonovine used for?

Methylergonovine is used to prevent or control bleeding after childbirth by helping the uterus contract. It is often administered to manage postpartum hemorrhage.

Methergine and oxytocin are not the same. They are both used in obstetrics but have different purposes and mechanisms of action. Methergine is an ergot alkaloid used to prevent or treat postpartum hemorrhage by causing uterine contractions. Oxytocin is a hormone that induces labor and controls bleeding after childbirth by stimulating uterine contractions.

When a patient is taking methylergonovine, it is important to monitor blood pressure, as the medication can cause hypertension. Additionally, monitoring for signs of ergotism, such as numbness, tingling, or pain in the extremities, is advised. It is also important to observe for any adverse cardiovascular effects, such as chest pain or arrhythmias. Regular assessment of uterine tone and bleeding is necessary to ensure the medication's effectiveness in managing postpartum hemorrhage.

Methergine is more commonly associated with causing hypertension rather than hypotension. However, in rare cases, it may cause hypotension, especially if administered intravenously too rapidly. It is important for healthcare providers to monitor blood pressure when administering this medication.

Methylergometrine is used to prevent or control excessive bleeding following childbirth. It works by stimulating uterine contractions, which helps to reduce blood loss after delivery.