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Mitosol is a medication used during certain glaucoma surgeries to improve outcomes. While it can be beneficial, it's important to be aware of specific risks associated with its use.

Mitosol is cytotoxic, meaning it can kill cells. If applied in concentrations higher than 0.2 mg/mL or for longer than two minutes, it may cause unintended damage to the cornea and sclera, potentially leading to thinning or perforation. Direct contact with the corneal endothelium can result in cell death.

The use of Mitosol has been linked to an increased incidence of post-operative hypotony, a condition where intraocular pressure becomes too low. This can lead to vision problems and other complications.

In patients who still have their natural lens (phakic patients), Mitosol use has been associated with a higher incidence of lens changes and cataract formation.

Mitosol can cause harm to a developing fetus. Women who are pregnant or may become pregnant should avoid exposure to this medication. Healthcare providers should verify pregnancy status in females of reproductive potential before using Mitosol.

Mitosol is contraindicated in patients who have previously shown hypersensitivity to mitomycin, the active ingredient. If you have a known allergy to mitomycin, inform your healthcare provider.

Healthcare workers who are pregnant or nursing should avoid handling Mitosol due to potential risks associated with exposure.

If Mitosol comes into contact with the skin or eyes, immediate action is necessary. For eye exposure, remove any contact lenses and flush the eyes with water for 15 minutes, keeping the eyelids open. For skin contact, wash the area thoroughly with water and non-abrasive soap. Seek medical attention if irritation persists.

Understanding these risks is crucial for both patients and healthcare providers to ensure the safe and effective use of Mitosol during glaucoma surgery.

Mitosol is a medication used during certain glaucoma surgeries to improve outcomes. While it can be beneficial, it's important to be aware of potential side effects associated with its use. Common Side Effects:

• Eye Irritation: Some patients may experience redness, discomfort, or a sensation of irritation in the treated eye.
• Vision Changes: Temporary blurred vision or other visual disturbances can occur after the procedure. Serious Side Effects:
• Hypotony: This refers to abnormally low eye pressure, which can lead to vision problems. Symptoms might include decreased vision or a sensation of heaviness in the eye.
• Cataract Formation: There is an increased risk of developing cataracts, especially in patients who still have their natural lens.
• Infections: Conditions like blebitis (infection of the filtering bleb) and endophthalmitis (a severe eye infection) can occur, leading to redness, pain, and potential vision loss.
• Corneal Damage: Damage to the cornea, the clear front part of the eye, can result in vision changes and discomfort. Other Potential Side Effects:
• Retinal Issues: Problems such as retinal detachment or bleeding can arise, leading to symptoms like flashes of light, floaters, or a shadow over part of the vision.
• Inflammation: Inflammatory reactions like iritis (inflammation of the iris) can cause eye pain and redness. It's crucial to monitor for any unusual symptoms after surgery involving Mitosol. If you experience significant eye pain, sudden vision changes, or signs of infection, contact your eye care professional immediately.