Opioid overdoseNaloxone coupons
Naloxone

Naloxone Coupons & Savings Card – Discount Prices from $62.21

Generic for: Narcan, Lifems naloxone, Kloxxado

Naloxone is an essential medication used for the emergency treatment of opioid overdose in both children and adults. It acts quickly to restore normal breathing within 2 to 3 minutes by blocking the effects of opioids on the brain, which can otherwise cause life-threatening symptoms like severe drowsiness, difficulty waking up, and respiratory problems. It is available without a prescription in two forms: a nasal spray (such as Kloxxado and Narcan) and an auto-injector (like Zimhi). It's important to note that the effects of naloxone are temporary, lasting only 30 to 90 minutes, so it's crucial to seek medical help immediately after administering the first dose, as overdose symptoms can recur. In addition to treating overdoses, naloxone can also be used intravenously to raise blood pressure in cases of septic shock and to address slowed breathing following surgery due to opioid use. Always consult with a healthcare professional for personalized medical advice.
Our coupons are free to use. Before paying, show the pharmacist your Naloxone savings card to get your free discount. Use our filters below to edit the prescription box to match your needs. The Naloxone prices will update based on your prescription needs. Above our Naloxone coupons, you can change your location to see pharmacy prices and costs in other areas. We're here to help you buy Naloxone at the lowest price with our prescription discount card.

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10ML of 4MG/10ML, Naloxone (1 Vial)

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CVS

$79.76

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Walmart

$62.21

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Walgreens

$62.60

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Naloxone savings card

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Walmart

$62.21

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Price history for Narcan (brand) & Naloxone (generic)

1 Vial, 10ML of 4MG/10ML

Average retail price for Narcan

Average retail price for Naloxone

Average SaveHealth price for Naloxone

Our price history data is based on aggregated prescription data collected from participating pharmacies in America. Our prescription data updates daily to reflect the latest price changes. If you notice a missing data point, it means there wasn't sufficient data available to generate a monetary value for that date.

We analyzed Naloxone prices for (10ML of 4MG/10ML, 1 Vial) over the last 12 months. The average retail price was $227.58, while the average price using the SaveHealth discount card was $64.81. That's a savings of approximately 71.52% when using our Naloxone coupon.

Compared to the generic version, Narcan had an average price of $2579.25 over the same time period. With the SaveHealth savings card, Naloxone is 97.49% cheaper on average than Narcan.

*Retail prices are based on pharmacy claims data, and may not be accurate when we don't have enough claims.

Naloxone dosage forms

Use our Naloxone 1ML of 0.4MG/ML coupon with prices from $5.01 for 1 Vial. You can also use our Naloxone 10ML of 4MG/10ML coupon with prices from $62.21 for 1 Vial.
DosageQuantityPrice fromPer unit
1ML of 0.4MG/ML1 Vial$5.01$5.01
10ML of 4MG/10ML1 Vial$62.21$62.21

Naloxone Warnings

The following safety information outlines critical warnings for the use of this medication. It is important to understand these risks and discuss any questions with your healthcare provider.

  • Opioid Withdrawal: Naloxone may induce sudden opioid withdrawal symptoms or reveal hidden pain in individuals who regularly use opioids or have been administered opioids during surgery. Symptoms can include general pain, abdominal discomfort, diarrhea, rapid heartbeat, fever, sweating, nausea, vomiting, irritability, and trembling. In infants, sudden withdrawal can be life-threatening, potentially leading to seizures, excessive crying, and abnormal reflexes. It is essential to inform your healthcare provider immediately and closely monitor these symptoms in anyone who has been administered naloxone. Risks include habitual opioid use, infants under one month old exposed to opioids, and opioid use during surgery.

  • Worsening of Opioid Overdose Symptoms: While naloxone can initially improve symptoms of an opioid overdose, these symptoms may worsen as naloxone's effects diminish within 30 to 90 minutes. Since opioids typically remain in the body longer, it is crucial to call emergency services during an opioid overdose. Remain with the affected individual after administering naloxone, regardless of apparent symptom improvement, until medical personnel arrive. This risk is heightened in those using long-acting opioids.

  • Limited Effectiveness: Naloxone might not be as effective in individuals using opioids with mixed receptor activities, such as buprenorphine. Multiple naloxone doses may be necessary to counteract such medications effectively. Ensure a new naloxone device or nasal spray is used for each additional dose. This situation is relevant for those taking pain medications containing buprenorphine or pentazocine.

  • Heart Problems: Naloxone can cause serious cardiac issues, such as seizures, irregular heartbeat, pulmonary edema, or blood pressure changes, especially in individuals with a history of heart problems or those on heart-affecting medications. Rarely, it may lead to brain complications, coma, or death. If planning a surgery involving opioid use, disclose your medical history to your healthcare provider in advance. Risks increase for individuals with a history of heart problems, those on heart-impacting medications, and opioid use during surgical procedures.

There are no specific contraindications listed for this medication. Always consult your healthcare provider for personalized advice.

Naloxone Side Effects

Common side effects:

  • Temporary increases in blood pressure
  • Headaches
  • Dry nose
  • Nasal congestion
  • Nose pain or swelling

Less common but important to monitor:

  • Nausea
  • Dizziness
  • Lightheadedness

Serious side effects:

  • Constipation
  • Stomach pain
  • Toothache
  • Muscle spasms
  • Muscle pain
  • Withdrawal symptoms
  • Seizures (in infants under four weeks)
  • Excessive crying (in infants under four weeks)
  • Muscle twitching (in infants under four weeks)
  • Allergic reaction (rash, swelling, severe dizziness, trouble breathing)

Naloxone Interactions

Naloxone is a medication used to rapidly reverse opioid overdoses by blocking the effects of opioids on the brain. While naloxone is generally safe and effective, it's important to be aware of how it interacts with other substances and medications.

Opioid Medications: Naloxone counteracts the effects of opioids such as morphine, Oxycodone, and heroin. In individuals dependent on these substances, administering naloxone can precipitate withdrawal symptoms, including nausea, vomiting, sweating, and increased heart rate. These symptoms, while uncomfortable, are typically not life-threatening and are preferable to the risks associated with opioid overdose.

Buprenorphine (Suboxone, Subutex): Buprenorphine is a medication used to treat opioid dependence. Naloxone can reduce the effectiveness of buprenorphine, potentially leading to withdrawal symptoms in some individuals. This interaction is particularly relevant when naloxone is administered to someone using buprenorphine as part of their treatment plan.

Clonidine (Catapres): Clonidine is often prescribed to manage high blood pressure or withdrawal symptoms. When used in combination with naloxone, clonidine may become less effective, which could impact blood pressure control.

Monoamine Oxidase Inhibitors (MAOIs): MAOIs, such as phenelzine and Tranylcypromine, are a class of antidepressants. Combining naloxone with MAOIs may lead to serious reactions, including serotonin syndrome or opioid toxicity. Therefore, the use of naloxone is not recommended for patients taking MAOIs or within 14 days of stopping such treatment.

Muscle Relaxants: Naloxone may enhance the effects of muscle relaxants, leading to increased respiratory depression. Patients receiving both medications should be closely monitored for signs of respiratory issues, and dosage adjustments may be necessary.

Diuretics: Opioids can reduce the efficacy of diuretics by inducing the release of antidiuretic hormone. While naloxone reverses opioid effects, monitoring for signs of diminished diuresis and adjusting diuretic dosage as needed is advisable.

Anticholinergic Drugs: The concurrent use of anticholinergic drugs with naloxone may increase the risk of urinary retention and severe constipation, potentially leading to paralytic ileus. Patients should be monitored for these side effects when both medications are used together.

Alcohol and Other Central Nervous System (CNS) Depressants: While naloxone is not known to interact directly with alcohol or other CNS depressants, it's important to note that these substances can exacerbate respiratory depression. Naloxone can reverse opioid-induced respiratory depression, but it does not counteract the depressant effects of alcohol or other non-opioid substances.

Health Conditions: Individuals with heart conditions should use naloxone with caution, as it can cause changes in blood pressure and heart rate. Pregnant or breastfeeding women should consult their healthcare provider before using naloxone, as its safety in these populations is not fully established.

It's crucial to inform your healthcare provider about all medications, supplements, and health conditions before using naloxone to ensure its safe and effective use.

Naloxone FAQs
What does the drug naloxone do?

Naloxone is a medication used to rapidly reverse opioid overdose. It works by binding to opioid receptors in the brain, displacing the opioids, and blocking their effects. This can quickly restore normal breathing in a person whose breathing has slowed or stopped due to opioid use. Naloxone is often administered in emergency situations and is available in various forms, including injectable and nasal spray.

Administering naloxone to someone who does not need it, such as a person not experiencing an opioid overdose, is generally safe. Naloxone is an opioid antagonist and has no effect on individuals who do not have opioids in their system. It is unlikely to cause harm, but it may lead to minor side effects like dizziness or headache. However, it is always important to use medications appropriately and consult healthcare professionals when in doubt.

Naloxone is available over the counter in many areas, but availability can vary depending on local regulations. It is advisable to check with local pharmacies or health departments for specific availability and guidelines in a particular area.

Narcan (naloxone) can be administered to someone who is breathing if there are signs of an opioid overdose, such as shallow or irregular breathing, unresponsiveness, or pinpoint pupils. It is important to monitor the person's breathing and responsiveness, and if there is any doubt about an overdose, administering Narcan is generally safe and can be life-saving. Always seek emergency medical help immediately after administering Narcan.

There are three main types of naloxone available for use:1. Injectable Naloxone: This form is typically administered via a syringe and needle, often used by healthcare professionals.2. Auto-Injector Naloxone: Known as Evzio, this is a pre-filled device that provides voice instructions for use, making it accessible for non-medical individuals in emergency situations.3. Nasal Spray Naloxone: Known as Narcan, this form is administered intranasally and is designed for easy use by the general public without the need for needles.