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This medication guide provides crucial safety information regarding the use of Nicorette (nicotine). It is essential to understand these potential risks and consult your healthcare provider for any personal concerns.

• Risks to Unborn and Breastfeeding Infants: If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider about the use of Nicorette (nicotine). Studies suggest that nicotine-replacement therapies, such as Nicorette (nicotine), can increase the risk of colic and ADHD in infants if used during pregnancy. Discuss alternative smoking cessation options with your provider, who may recommend support groups or programs to help you quit smoking.

• Exacerbation of Pre-existing Conditions: Do not use Nicorette (nicotine) if you have certain medical conditions unless your healthcare provider has confirmed it is safe. Nicorette may aggravate existing conditions, leading to severe side effects. Ensure your healthcare provider is informed of your complete medical history before beginning Nicorette (nicotine). Conditions of concern include heart-related issues, recent heart attack, irregular heartbeat, uncontrolled high blood pressure, diabetes, stomach ulcers, skin disorders, and a history of seizures.

• Caution for Individuals with Phenylketonuria (PKU): The Nicorette (nicotine) lozenges contain phenylalanine, derived from the artificial sweetener aspartame. If you have phenylketonuria (PKU), using these lozenges can be harmful. Inform your healthcare provider about your condition so that they can recommend a safer form of Nicorette (nicotine) for you.

Please reach out to your healthcare provider for personalized advice and more information tailored to your specific health needs.

When using this medication, some individuals may experience common side effects such as sore jaw, stomach upset, hiccups, or excessive saliva production. Nausea, vomiting, and feeling lightheaded are also possible, and these symptoms are typically mild. If they persist or worsen, it is advisable to consult with a healthcare provider for reassurance and guidance.

In addition to these, users might also encounter mouth and throat irritation, heartburn, headache, or cough. While these effects are generally manageable, they should be monitored closely. Chewing the gum too quickly can lead to lightheadedness, dizziness, hiccups, or nausea; slowing down or adjusting the chewing technique may alleviate these symptoms.

More serious side effects, although rare, demand immediate medical attention. These include severe dizziness, mental or mood changes such as irritability or vivid dreams, numbness or tingling in the extremities, and swelling of the hands, ankles, or feet. Very serious reactions like chest pain, confusion, severe headache, rapid or irregular heartbeat, trouble speaking, or muscle weakness on one side of the body require urgent care.

Allergic reactions, though infrequent, can occur and present as rash, itching, swelling, particularly of the face, tongue, or throat, and difficulty breathing. Immediate medical help is crucial if these symptoms arise. While this summary covers the most reported side effects, any new or unexplained symptoms should prompt a discussion with a healthcare provider to ensure safety and proper care.

If you're planning to quit smoking, it's important to know that this change can affect how your liver processes certain medications, including those like acetaminophen, caffeine, insulin, oxazepam, pentazocine, propoxyphene, propranolol, theophylline, and tricyclic antidepressants such as amitriptyline and imipramine, as well as diuretics like furosemide. Therefore, it's crucial to inform all your healthcare providers, including doctors and pharmacists, about your decision to stop smoking.

Additionally, Nicorette (nicotine) may interact with specific medications or supplements. It's essential to discuss all the medications and supplements you are currently taking with your doctor and pharmacist, including both prescription and over-the-counter drugs, as well as vitamins and herbal supplements. Although the following list is not exhaustive, some medications that may require special attention when used with Nicorette include Bendamustine, Hemin, and Tegafur. If these medications are required, your doctor might adjust the dosage or frequency to ensure safe and effective use.