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When taking this medication, you might experience mild side effects such as nausea, vomiting, headaches, bloating, breast tenderness, or swelling in the ankles and feet due to fluid retention. Weight changes and irregularities in your menstrual cycle, like spotting or missed periods, can also occur, particularly in the early months of use. These effects are generally manageable, but if they persist or worsen, consult a healthcare professional.

Monitor your blood pressure regularly, as this medication can cause an increase. If you notice elevated readings, seek medical advice. It is crucial to contact a healthcare provider immediately if you encounter severe side effects, including lumps in the breast, significant mood changes, intense abdominal pain, or unusual vaginal bleeding patterns. Additionally, signs of liver issues such as dark urine or yellowing of the eyes and skin require prompt medical attention.

Rare but serious risks include the development of blood clots, which can lead to life-threatening conditions like heart attacks or strokes. Immediate medical help is needed if you experience chest pain, sudden dizziness, difficulty speaking, severe headaches, or vision changes. Allergic reactions to this medication are uncommon, but urgent care is necessary if you observe symptoms like rash, swelling, or difficulty breathing. Always communicate with a healthcare provider if you experience side effects not listed here.

Certain medications can interact with this drug. These include aromatase inhibitors like Anastrozole and Exemestane, as well as fezolinetant, ospemifene, Tamoxifen, Tizanidine, Tranexamic Acid, and some combination treatments for chronic hepatitis C (such as ombitasvir/paritaprevir/Ritonavir, with or without dasabuvir).

Additionally, some drugs might reduce the effectiveness of hormonal birth control by lowering hormone levels, which could lead to pregnancy. Such drugs include griseofulvin, Modafinil, rifamycins (like Rifampin and Rifabutin), ritonavir, St. John's wort, and certain medications for seizures (such as barbiturates, Carbamazepine, Felbamate, Phenytoin, Primidone, and Topiramate), as well as some HIV medications (like nelfinavir and Nevirapine).

Always inform your doctor about any new medications you start and discuss whether you need additional forms of birth control. If you notice unusual spotting or breakthrough bleeding, contact your doctor, as these could indicate ineffective birth control.

This drug might also affect the results of some lab tests (including those for blood clotting and thyroid function), potentially leading to incorrect results. Be sure to tell lab personnel and all your healthcare providers that you are taking this medication.