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The following safety information is crucial for anyone considering or currently using Necon 7/7/7. It outlines potential risks, necessary precautions, and specific instructions for certain populations. Please consult your healthcare provider if you have any questions or concerns.

• Heart Problems and Strokes: Necon 7/7/7 may increase the risk of significant heart problems, especially in smokers over the age of 35. The risk is heightened with age, heavy smoking, and in individuals with high blood pressure, high cholesterol, obesity, or diabetes. Women over 35 who smoke are advised against using Necon 7/7/7.

• Blood Clots: There is an elevated risk of blood clots, particularly during the first year of use or when resuming after a four-week break. This risk is higher if you are undergoing surgery, immobile for extended periods, or have recently had a baby. It is recommended to cease using Necon 7/7/7 at least four weeks before and two weeks after surgery or while on bed rest. Do not start the medication until four weeks post-delivery if not breastfeeding. Immediate medical attention is needed if you experience sharp chest pain, coughing up blood, shortness of breath, or leg pain.

• High Blood Sugar and Cholesterol: Use of Necon 7/7/7 may lead to increased blood sugar and cholesterol levels. Individuals with diabetes, prediabetes, or high cholesterol should consult their provider prior to use, as regular monitoring will be necessary.

• High Blood Pressure: Necon 7/7/7 can elevate blood pressure, especially in older individuals or those on long-term birth control. Women with very high blood pressure should avoid hormonal contraceptives like Necon 7/7/7. If blood pressure exceeds 160/100 mmHg and remains uncontrolled, a different birth control method should be considered. Blood pressure typically normalizes after discontinuation.

• Breast and Cervical Cancer Risk: There is a potential, albeit mixed, association between Necon 7/7/7 and an increased risk of breast and cervical cancer, especially for those with a history of breast cancer or long-term COC use.

• Liver Problems: Individuals with liver conditions, such as viral hepatitis, severe liver scarring, or liver tumors, should not use Necon 7/7/7. Although rare, the medication can increase the risk of benign liver tumors. Discontinue use and consult your provider if symptoms like jaundice, fever, fatigue, appetite loss, or dark urine occur.

Contraindications

Necon 7/7/7 should not be used under the following conditions as it may pose serious health risks. Consult your healthcare provider if any of these apply:

• History or presence of blood clots
• Conditions increasing the likelihood of clotting
• History of heart attack or stroke
• Heart valve issues with complications
• Consistent high blood pressure over 160/100 mmHg
• Diabetes with vascular complications
• Severe headaches with neurological symptoms
• Major surgery necessitating prolonged immobility
• History or current breast cancer
• Uterine lining cancer
• Estrogen-dependent tumors
• Undiagnosed abnormal vaginal bleeding
• Jaundice during pregnancy or previous medication use
• Liver disease or cancer
• Pregnancy
• Concurrent use of hepatitis C treatments containing ombitasvir, paritaprevir, and ritonavir, with or without dasabuvir.

Please ensure you thoroughly discuss these warnings and contraindications with your healthcare provider before taking Necon 7/7/7.

Common side effects:

• Nausea
• Vomiting
• Stomach cramps
• Bloating
• Changes in menstrual cycles
• Bleeding between periods
• Spotting
• Changes in flow
• Missing periods

Serious side effects:

• Symptoms of a heart attack
• Chest pain
• Stomach discomfort
• Sweating
• Nausea
• Dizziness
• Stroke symptoms
• Sudden numbness or weakness
• Confusion
• Trouble with vision
• Headache
• Difficulty walking
• Signs of deep vein thrombosis
• Leg cramps
• Swelling
• Pain
• Muscle tightness
• Pulmonary embolism symptoms
• Cough
• Trouble breathing
• Racing heart

When taking Nortrel 7/7/7, it's important to be aware of potential interactions with other medications, foods, and health conditions that could affect its effectiveness or increase the risk of side effects.

Drug Interactions:

• Medications That May Reduce Effectiveness: Certain drugs can decrease the effectiveness of Nortrel 7/7/7, potentially leading to unintended pregnancy. These include some seizure medications (like Carbamazepine and Phenytoin), antibiotics (such as Rifampin), and herbal supplements like St. John's wort. If you're prescribed any of these, discuss alternative contraceptive methods with your healthcare provider.

• Medications Affected by Nortrel 7/7/7: This contraceptive can influence the levels of other medications in your body. For instance, it may increase the blood levels of corticosteroids like Methylprednisolone, potentially intensifying their side effects.

Food and Lifestyle Interactions:

• Grapefruit Juice: Consuming grapefruit juice can raise the blood levels of norethindrone, one of the active ingredients in Nortrel 7/7/7. This might heighten the risk of side effects. It's advisable to limit or avoid grapefruit juice while taking this medication.

• Caffeine: Ethinyl estradiol, another component of Nortrel 7/7/7, may increase the effects of caffeine. If you consume caffeine regularly, be mindful of potential increased sensitivity.

Health Conditions:

• High Blood Pressure: Nortrel 7/7/7 can elevate blood pressure. If you have hypertension, your doctor may need to monitor your blood pressure more closely or consider alternative contraceptive options.

• High Cholesterol: This medication may affect cholesterol levels, particularly by increasing triglycerides. If you have high cholesterol, discuss this with your healthcare provider to determine the best course of action.

Always inform your healthcare provider about all medications, supplements, and health conditions before starting Nortrel 7/7/7 to ensure it's safe and effective for you.