Osphena

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Osphena (ospemifene) is a medication designed to alleviate symptoms of vaginal dryness and painful intercourse that women may experience after menopause. It functions by mimicking estrogen in certain parts of the body, addressing the reduction in estrogen levels that occurs during menopause. This decline in estrogen can lead to dryness and irritation of the vaginal lining, making sexual activity uncomfortable. Osphena is classified as a selective estrogen receptor modulator (SERM) and is taken orally once daily. Common side effects may include hot flashes and vaginal discharge. Always consult with a healthcare professional before starting any new medication to ensure it is appropriate for your individual health needs.
Our Osphena coupons are free to use. You can print the coupon, email it to yourself, or receive the Osphena coupon via text message. To get your free discount, show the pharmacist your Osphena savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Osphena prices will update based on your prescription needs. Above our Osphena coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Osphena savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.

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60MG, Osphena (30 Tablets)

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CVS

$99.00

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Osphena savings card

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CVS

$99.00

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Osphena dosage forms

The average cost for 30 Tablets of Osphena at 60MG is $232 with a free coupon. This is 27.28% off the average retail price of $850.39
DosageQuantityPrice fromPer unit
60MG30 Tablets$232$7.73

Osphena Warnings

Ospemifene Safety and Warning Information

When considering the use of ospemifene, it is crucial to be aware of its potential risks and necessary precautions. Below is a summary of important safety information:

  • Uterine and Endometrial Cancer Risk: Ospemifene can mimic the effects of estrogen in the uterus, potentially leading to an increased risk of uterine or endometrial cancer. This is especially significant for individuals undergoing estrogen therapy without the addition of progestin, or those using it for more than a year. Notify your healthcare provider immediately if you experience any changes in your menstrual cycle, unusual vaginal bleeding or discharge, or any pain or pressure in the lower abdomen.

  • Blood Clots, Stroke, and Heart Attack: Although rare, ospemifene has been associated with the formation of serious blood clots, which could result in a heart attack or stroke. It is important to inform your doctor of your complete medical history, including any previous blood clot incidents, high blood pressure, high cholesterol, diabetes, tobacco use, alcohol consumption, or heart disease, as these may elevate your risk.

  • Breast Cancer Considerations: The effects of ospemifene on breast cancer risk are not well-studied. Thus, it is advised not to use this medication if you have a current or past diagnosis of breast cancer. Regular self-examinations and scheduled mammograms are recommended to monitor any changes in breast health.

  • Contraindications: Avoid using ospemifene if you have abnormal vaginal bleeding, estrogen-dependent tumors, a history of blood clots, strokes, or heart attacks, or if you are currently pregnant or may become pregnant.

In case of an overdose or suspected adverse reaction, seek immediate medical attention. Always discuss any concerns or questions with your healthcare provider to ensure this medication is safe and suitable for your use.

Osphena Side Effects

When taking this medication, you may experience common side effects such as hot flashes, vaginal discharge, muscle spasms, headaches, excessive sweating, and night sweats. These effects are usually mild, but if they persist or worsen, it is advisable to consult your healthcare provider for guidance.

In rare instances, this medication can cause serious side effects that require immediate medical attention. These include blood clots, which can manifest as swelling, pain, or tenderness in the arm or leg, or warmth of the skin. If you experience trouble breathing, chest pain, or symptoms resembling a heart attack, such as arm pain, shortness of breath, or cold sweats, seek urgent care. Additionally, if you notice any signs of a stroke—such as sudden weakness on one side of the body, facial droop, difficulty speaking, vision changes, confusion, or a severe headache—immediate medical help is necessary.

Abnormal vaginal bleeding that persists or recurs should also be promptly addressed with your healthcare provider. While a serious allergic reaction is rare, be aware of symptoms like rash, itching, swelling (particularly of the face, tongue, or throat), severe dizziness, or trouble breathing, and seek emergency medical assistance if they occur. Always report any other unusual effects to your healthcare provider.

Osphena Interactions

Ospemifene, marketed as Osphena, has the potential to interact with various medications and supplements. It is important to inform your doctor and pharmacist about all the medicines and supplements you are currently taking, including prescription, over-the-counter, vitamins, and herbal products, to prevent possible interactions.

Certain drugs can alter the way ospemifene is eliminated from your body, potentially affecting its efficacy. Medications such as Fluconazole and Rifampin are known to influence ospemifene's removal. If these drugs are prescribed alongside ospemifene, your doctor might adjust the dosage or frequency of use to ensure safety and effectiveness.

Additionally, ospemifene may interact with estrogens and tibolone. Using ospemifene with these drugs is generally not recommended unless necessary. In such cases, your healthcare provider may need to modify dosing schedules.

Moreover, ospemifene can potentially increase the risk of side effects when used with medications like Amiodarone, Clarithromycin, and Ketoconazole, among others. While these combinations might be required for your treatment, your doctor will carefully adjust the doses and monitor your therapy to manage any increased risk.

Always consult your healthcare provider for personalized advice and before making any changes to your medication regimen.

Osphena FAQs
What does Osphena actually do?

Osphena is a medication used to treat moderate to severe dyspareunia, which is pain during sexual intercourse, and vaginal dryness due to menopause. It works by acting as an estrogen agonist/antagonist, helping to improve the condition of vaginal tissues and alleviate symptoms associated with menopause.

The safety of Osphena compared to estrogen depends on the individual's health profile and specific medical conditions. Osphena is a selective estrogen receptor modulator (SERM) used to treat moderate to severe dyspareunia due to menopause, while estrogen therapy is often used for a broader range of menopausal symptoms. Both treatments have potential risks and benefits. Osphena may have a lower risk of certain side effects associated with estrogen, such as breast cancer, but it can increase the risk of thromboembolic events and stroke. It is important for individuals to consult with their healthcare provider to determine the most appropriate and safe treatment option based on their personal health history and needs.

Osphena is not available over the counter. It requires a prescription from a healthcare provider.

Ospemifene is classified as a selective estrogen receptor modulator (SERM).

Osphena (ospemifene) is not commonly associated with hair loss as a side effect. However, if an individual experiences unexpected hair loss while taking Osphena, it is advisable to consult with a healthcare provider to determine the cause and discuss any concerns.