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The following safety and warning information is crucial for users of Pulmicort Flexhaler (budesonide). It is important to review these details carefully and discuss any concerns with your healthcare provider.

• Not for Immediate Asthma Relief: Do not use Pulmicort Flexhaler during an asthma attack, as it does not provide quick relief. A rescue inhaler, such as albuterol, should be used instead for breathing difficulties.

• Risk of Oral Fungal Infection: Pulmicort Flexhaler can lead to thrush, a fungal infection in the mouth and throat. To minimize this risk, rinse your mouth with water and spit out after each use. Contact your pulmonologist if you experience symptoms such as white patches, a cotton-like feeling in the mouth, pain during eating or swallowing, or loss of taste, as treatment may be needed.

• Bronchospasm Warning: Inhaled medications like Pulmicort Flexhaler can occasionally cause bronchospasm, leading to wheezing, coughing, or difficulty breathing. If this occurs, use your rescue inhaler and seek medical attention promptly.

• Increased Infection Risk: Pulmicort Flexhaler may weaken the immune system, raising the risk of infections, including respiratory infections and pneumonia. Inform your healthcare provider if you are on other immunosuppressive medications or being treated for serious infections like tuberculosis.

• Changes in Stress Hormone Levels: Overuse of Pulmicort Flexhaler can lead to elevated stress hormone levels, potentially causing increased blood sugar or blood pressure. Adhere strictly to prescribed dosages.

• Impact on Child Growth: Children using Pulmicort Flexhaler may experience growth delays. Healthcare providers will prescribe the minimal effective dose and monitor growth regularly.

• Potential Bone Density Reduction: Long-term use may lower bone mineral density. Elderly individuals, those with a family history of osteoporosis, or those on certain medications should discuss fracture risk with their healthcare provider.

• Eye and Vision Concerns: Prolonged use may increase the risk of eye pressure, glaucoma, or cataracts. Consult with your optometrist if you have a history of these conditions or notice vision changes.

• Allergic Reactions: Potential allergic reactions include hives, rash, facial swelling, or anaphylaxis. Seek immediate medical attention if these symptoms occur, particularly if allergic to milk proteins.

Contraindications:

• Pulmicort Flexhaler should not be used to treat sudden, severe asthma attacks or by individuals allergic to lactose or milk proteins. Consult your healthcare provider if these contraindications apply to you.

When taking this medication, some individuals may experience common side effects such as a dry or irritated throat, hoarseness, voice changes, nausea, a bad taste in the mouth, a runny or stuffy nose, or nosebleeds. These are typically mild and often resolve on their own; however, if they persist or worsen, it is advisable to consult your healthcare provider for advice.

In some cases, users may encounter other side effects like allergic rhinitis, viral upper respiratory tract infections, or nausea. Additionally, conditions such as stomach flu, middle ear infections, or oral thrush may occur. Oral thrush, characterized by white patches in the mouth or on the tongue, warrants contacting your healthcare provider.

More serious side effects are rare but require immediate medical attention. These include sudden breathing difficulties or asthma attacks shortly after using the medication. If this happens, use a quick-relief inhaler and seek medical help immediately. The drug can also weaken the immune system, potentially increasing the risk of serious infections. Be vigilant for signs of infection such as ear pain, sore throat, fever, or chills, and consult your doctor if they occur.

Severe allergic reactions, although uncommon, can manifest as rash, swelling (particularly of the face, tongue, or throat), severe dizziness, or trouble breathing. Immediate medical assistance is necessary if these symptoms develop. Other serious side effects requiring prompt attention include unusual tiredness, vision problems, easy bruising or bleeding, a puffy face, unusual hair growth, mood changes, muscle weakness, thinning skin, slow wound healing, or increased thirst or urination. Always remain alert for any other effects not listed here and discuss them with your healthcare provider.

When using Pulmicort Flexhaler (budesonide), it's important to be aware of potential drug interactions. Inform your doctor and pharmacist about any other medications or supplements you are taking, whether they are prescription, over-the-counter, vitamins, or herbal supplements.

Certain drugs should not be used with budesonide, such as Desmopressin, as the combination is generally not recommended. Other medications, including a range of anti-inflammatory drugs like Ibuprofen and Naproxen, as well as some antibiotics like Erythromycin and Ciprofloxacin, may require careful monitoring and dose adjustments if used concurrently with budesonide.

Additionally, budesonide can interfere with lab tests, leading to inaccurate results. Ensure that your healthcare providers and lab personnel are informed if you are using this medication. Always consult your healthcare professional before starting or stopping any medication.