Tenofovir Disoproxil Fumarate Coupons & Discount Card - Compare Prices Near You

Patients and healthcare providers should take note of the following important safety information regarding the use of tenofovir disoproxil fumarate (Viread). It is crucial to understand the potential risks and necessary precautions associated with this medication.

• Worsening of Hepatitis B Infection: If you have a hepatitis B virus (HBV) infection, discontinuing tenofovir disoproxil fumarate (Viread) abruptly may worsen your liver condition, known as an HBV flare-up. It is essential to consult your healthcare provider before stopping this medication. Ensure timely refills to avoid treatment interruption. If discontinuation is necessary, your healthcare provider will monitor your liver function through blood tests for several months to check for any flare-up.

• Kidney Problems: There is a risk of developing kidney issues while taking tenofovir disoproxil fumarate (Viread), which could occur soon after starting the treatment or over time. To minimize this risk, avoid using other medications that can harm the kidneys, such as high doses of non-steroidal anti-inflammatory drugs (NSAIDs). Regular blood or urine tests will be conducted to assess kidney function. Report any persistent bone or muscle pain, pain in your arms or legs, or general weakness to your healthcare provider, as these could be indicators of kidney problems.

• Overactive Immune System: The medication may cause immune reconstitution syndrome, where the immune system becomes more active and starts fighting infections it couldn't before treatment. In rare cases, the immune system may attack normal body cells. This condition can manifest within weeks or months of starting treatment. Notify your healthcare provider immediately if you experience new symptoms such as fever, pain, hair loss, bulging eyes, or excessive sweating.

• Bone Problems: Individuals taking tenofovir disoproxil fumarate (Viread) for HIV may experience decreased bone mineral density and bone loss, increasing the risk of osteoporosis and fractures. Those with kidney issues may also encounter joint or muscle pain. Your provider may recommend bone density tests and discuss the use of calcium and vitamin D supplements to maintain bone health.

• Liver Problems and Lactic Acidosis: Although rare, liver problems can occur with the use of NRTIs like tenofovir disoproxil fumarate (Viread), especially in patients with hepatitis B or C. Discuss your medical history with your provider to ensure safe use of the medication.

• Interactions with Other Medications: Certain hepatitis C medications, such as Epclusa (sofosbuvir/velpatasvir), may increase tenofovir disoproxil fumarate (Viread) levels in your body, exacerbating side effects like rash, diarrhea, and nausea. Your healthcare provider will monitor these interactions to ensure your safety.

In case of concerns or symptoms that may indicate adverse effects, contact your healthcare provider for guidance. Always follow professional medical advice when managing your treatment with tenofovir disoproxil fumarate (Viread).

Common side effects:

• Dizziness
• Diarrhea
• Headache
• Trouble sleeping
• Rash
• Higher cholesterol
• Increased creatine kinase levels
• Pain
• Nausea
• Lack of energy

Less common but important to monitor:

• Back pain
• Fever
• Upper respiratory or sinus infections
• Stomach pain
• Anxiety
• Vomiting
• Joint pain

Serious side effects:

• Lactic acidosis symptoms (extreme tiredness, belly pain, muscle pain, breathing difficulties)
• Serious kidney problems (confusion, decreased urination, swelling in the legs, joint or bone pain)
• Liver issues (nausea, vomiting, loss of appetite, abdominal pain, jaundice, changes in urine or stool color)
• Resurgence of previous infections or overactive immune response
• Severe allergic reactions (rash, itching, swelling, severe dizziness, trouble breathing)
• Unexplained weight loss, severe fatigue, persistent headaches, numbness, vision changes
• Symptoms indicative of an overactive thyroid or Guillain-Barre syndrome

Interactions with high risk of serious adverse effects and should be avoided:

• Other products containing tenofovir
• Atazanavir

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Adefovir
• Orlistat
• Aminoglycosides (e.g., amikacin, gentamicin)