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Atazanavir

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generic Reyataz

Atazanavir, sold under the brand name Reyataz, is a medication used in combination with other antiretroviral drugs to manage HIV infections. This drug is part of the protease inhibitor class, which works by blocking the protease enzyme. By doing so, it prevents HIV from processing proteins that are necessary for the virus to multiply and infect healthy cells. This helps to reduce the amount of the virus in the body, allowing the immune system to function more effectively, thereby lowering the risk of HIV-related complications such as infections and cancer, and enhancing overall quality of life. Atazanavir is typically taken with a "booster" like ritonavir or cobicistat to enhance its effectiveness. While it is not a cure for HIV, it plays a crucial role in controlling the infection. Patients are advised to continue following their prescribed treatment plan and use preventative measures during sexual activity, such as condoms, to reduce the risk of transmitting the virus. Some common side effects of atazanavir include nausea, vomiting, and headache. In rare cases, it may cause jaundice, a condition that results in yellowing of the skin or eyes. Patients should consult their healthcare provider for personalized advice and to discuss any potential side effects or concerns.
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150MG, Atazanavir (30 Capsules)

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CVS

$32.58

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Rite Aid

$111.25

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Walgreens

$209.69

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$218.01

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Atazanavir savings card

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CVS

$32.58

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Atazanavir dosage forms

The average cost for 30 Capsules of Atazanavir (generic Reyataz) at 150MG is $32.46 with a free coupon. This is 3.99% off the average retail price of $814.2
DosageQuantityPrice fromPer unit
150MG30 Capsules$32.46$1.08
200MG30 Capsules$27.75$0.93
300MG30 Capsules$32.46$1.08

Atazanavir Warnings

This document outlines essential safety warnings and precautions for using Atazanavir (Reyataz). It is crucial to review this information carefully and discuss any questions or concerns with your healthcare provider.

  • Heart Rhythm Disturbances: Atazanavir can potentially disrupt heart rhythms, potentially leading to severe and life-threatening conditions. Individuals with a history of heart issues, imbalanced electrolyte levels, or those taking other heart-affecting medications like digoxin (Lanoxin) are at increased risk. Seek immediate medical help if you experience chest pounding, difficulty breathing, chest pain, or feel faint or dizzy.

  • Severe Skin and Allergic Reactions: Users may develop rashes or severe skin conditions, especially within the first 8 weeks. Mild to moderate rashes should be reported to your healthcare provider, but continuation of the medication is usually possible. However, if a severe rash is accompanied by fever, discomfort, muscle or joint pain, mouth sores, blisters, or facial swelling, discontinue the medication and seek medical attention immediately.

  • Liver Complications: Atazanavir may cause serious liver issues, including an increase in bilirubin levels leading to jaundice. Healthcare providers will conduct blood tests before and during treatment to monitor liver health. Report any symptoms such as drowsiness, nausea, loss of appetite, pale stools, upper right abdominal pain, jaundice, or dark urine promptly. Individuals with hepatitis B or C or a history of liver problems are at higher risk.

  • Kidney Concerns: This medication can harm the kidneys, making it unsuitable for those with existing kidney problems or at risk of them. Regular blood tests will monitor kidney function. Inform your provider about all medications you're taking, including over-the-counter ones, as many can negatively impact kidney health. Avoid Atazanavir if undergoing dialysis.

  • Risk of Stones: There is a rare risk of developing kidney stones or gallstones. If you experience lower abdominal or back pain, nausea, or vomiting, contact your provider immediately.

  • Elevated Blood Sugar: Atazanavir, particularly when combined with certain HIV medications, can increase blood sugar levels or exacerbate diabetes. Inform your provider if you have a history of diabetes, as adjustments to diabetes medications may be necessary. Regular blood sugar monitoring may be advised.

  • Overactive Immune System: Atazanavir may induce immune reconstitution syndrome, where the immune system becomes overly active and may attack healthy cells. This can occur shortly after beginning treatment or months later. Report any new symptoms like fever, pain, hair loss, bulging eyes, or sweating to your healthcare provider.

  • Body Fat Changes: In rare cases, Atazanavir may cause changes in body fat distribution. Notify your healthcare provider if you notice unusual fat accumulation or loss.

  • Bleeding Risks: Those with hemophilia or bleeding disorders may experience increased bleeding after starting Atazanavir. Approximately half the time, treatment can continue after bleeding ceases. Report any unexpected bleeding or difficulties in stopping bleeding to your provider.

  • Drug Interactions: Certain medications can affect how Atazanavir is metabolized, altering its efficacy and side effect profile.

Contraindications: Do not use this medication if you are taking certain other drugs metabolized by liver enzymes CYP3A4 or UGT1A1, such as alfuzosin (Uroxatral), rifampin (Rifadin), lovastatin, or simvastatin (Zocor).

Consultation with a healthcare provider is crucial before starting Atazanavir, especially if any of the above risks or conditions apply to you.

Atazanavir Side Effects

Common side effects:

  • Headaches
  • Nausea
  • Vomiting
  • Belly pain
  • Nerve pain
  • Diarrhea
  • Increased liver enzyme levels
  • Increased cholesterol levels
  • Jaundice
  • Rash

Less common but important to monitor:

  • Trouble sleeping
  • Dizziness
  • Fever
  • Feelings of depression

Serious side effects:

  • Severe allergic reactions
  • Serious liver issues
  • Abnormal heart rhythms
  • Overactive immune response
  • Overactive thyroid
  • Guillain-Barre syndrome
  • Changes in body fat distribution

Atazanavir Interactions

Interactions with high risk of serious adverse effects and should be avoided:

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

Atazanavir FAQs
Why is ritonavir combined with atazanavir?

Ritonavir is combined with atazanavir to boost the levels of atazanavir in the blood. Ritonavir acts as a pharmacokinetic enhancer by inhibiting the enzyme CYP3A4, which metabolizes atazanavir. This allows for higher concentrations of atazanavir, improving its efficacy in treating HIV.

Yes, atazanavir is an antiretroviral medication. It is used in the treatment of HIV infection.

The cost of atazanavir can vary depending on factors such as the pharmacy, location, insurance coverage, and whether a generic version is available. It is recommended to check with local pharmacies or insurance providers for the most accurate and up-to-date pricing information.

The cost of antiretroviral drugs can vary widely depending on several factors, including the specific medication, the country or region, whether the patient has insurance, and the availability of generic versions. In some countries, these medications may be provided at low or no cost through government programs or non-profit organizations. For the most accurate and up-to-date information, it is recommended to consult a healthcare provider or a local pharmacy.

The most common side effect of atazanavir is jaundice, which is characterized by yellowing of the skin or eyes. This occurs due to an increase in bilirubin levels in the blood.