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When using the medication loteprednol (Lotemax), it is crucial to be aware of the following safety warnings and precautions. Carefully review this information, and consult your healthcare provider if you have any concerns or questions.

• High Eye Pressure (Glaucoma): Long-term use of steroid eye medications like loteprednol can increase eye pressure, leading to glaucoma, which may damage eye nerves and impair vision. Notify your healthcare provider immediately if you experience persistent eye pain, discomfort, or changes in vision. Regular eye pressure monitoring is advised if using loteprednol for an extended period, especially if you have a history of glaucoma.

• Cataracts: Using steroid eye medications such as loteprednol can lead to cataracts. Contact your healthcare provider if you notice worsening vision or see glares or halos around lights at night. If you've recently undergone cataract surgery, limit use of loteprednol to no more than two weeks and schedule regular follow-ups.

• Infections: Steroids, including loteprednol, can weaken the immune system, increasing the risk of fungal or viral eye infections. Symptoms may be masked or exacerbated by the medication. If your eye condition worsens while using loteprednol, or if symptoms do not improve within a few days, consult your healthcare provider. Follow-up is necessary if you feel the need for a refill after finishing your prescription.

• Eye Injury or Damage: Loteprednol can thin certain parts of the eye, such as the cornea or sclera, increasing the risk of tears and more severe damage, especially with prolonged use. Those with naturally thin corneas or sclera, or recent cataract surgery, may be at higher risk. Seek immediate medical attention if you experience eye pain, excessive tearing, or deteriorating vision.

• Contact Lens Use: Avoid wearing contact lenses after recent eye surgery or when experiencing eye inflammation or allergies. Consult your provider regarding contact lens use during loteprednol treatment. If permitted, be aware that the preservative benzalkonium chloride in some forms of loteprednol can damage soft contact lenses. Remove lenses before application and wait at least 15 minutes post-application before reinsertion.

Contraindications: Loteprednol should not be used under the following conditions, as it may pose serious health risks. Consult your healthcare provider if you have:

• An eye infection caused by viruses, fungi, or mycobacteria.
• A known allergy to loteprednol, other corticosteroids, or any ingredient in loteprednol (Lotemax).

Alrex (loteprednol etabonate ophthalmic suspension) is a corticosteroid eye drop used to treat inflammation and allergic reactions in the eyes. While Alrex is applied directly to the eye and has minimal systemic absorption, it is important to be aware of potential interactions with other medications and health conditions.

Currently, there are no well-documented drug interactions between Alrex and other medications. However, this does not guarantee that no interactions exist. Therefore, it is essential to inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter products, and herbal supplements.

In addition to potential drug interactions, certain health conditions may affect the safety and effectiveness of Alrex. For instance, individuals with existing eye infections should avoid using Alrex, as corticosteroids can exacerbate infections. Prolonged use of Alrex may also increase intraocular pressure, potentially leading to glaucoma, and can contribute to the development of cataracts. Regular monitoring by an eye care professional is recommended during treatment to detect and manage these potential side effects.

Always consult your healthcare provider before starting or stopping any medication, including Alrex, to ensure it is appropriate for your specific health needs and to minimize the risk of adverse interactions or side effects.