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Ticagrelor is a medication that may lead to serious, potentially fatal bleeding. It is important to inform your healthcare provider about your complete medical history, particularly if you have any bleeding disorders. Before undergoing any surgical procedures, make sure to inform your doctor or dentist about all medications you are using, including ticagrelor. Your healthcare provider will provide specific instructions regarding the timing of when to stop this medication prior to surgery.

This medication is generally taken alongside low-dose aspirin, typically 75-100 milligrams per day. It is crucial not to exceed 100 milligrams of aspirin daily unless directed by your healthcare provider, as higher doses can reduce the effectiveness of ticagrelor.

Key Warnings and Precautions:

• Bleeding Risk: Ticagrelor acts as a blood thinner, increasing the risk of bleeding. You may notice prolonged bleeding or easier bruising. Be cautious if you are using other medications that may further increase bleeding risk, such as antiplatelets, anticoagulants, NSAIDs, and corticosteroids.

• Heart Attack Risk if Stopped Abruptly: Do not discontinue ticagrelor without professional guidance, as premature cessation can increase the risk of blood clots, heart attack, or stroke. Consult your healthcare provider to safely plan any cessation.

• Shortness of Breath: Some individuals may experience mild to moderate shortness of breath, which typically resolves with continued use. If it becomes bothersome, contact your healthcare provider but continue the medication as directed.

• Slow Heart Rate: Inform your healthcare provider if you have a history of irregular heart rhythms or conditions that cause a slow heart rate.

• Sleep Apnea: Ticagrelor has been associated with sleep apnea. If you experience symptoms such as daytime sleepiness, difficulty concentrating, or frequent headaches, report these to your healthcare provider.

Contraindications:

Avoid using ticagrelor if you have a history of brain bleeds or active bleeding. Consult your healthcare provider if these conditions apply to you before starting this medication.

In the event of an overdose, seek immediate medical attention. Always follow the guidance provided by your healthcare provider for safe and effective use of ticagrelor.

When taking this medication, some individuals may experience common side effects such as shortness of breath, dizziness, nausea, and nosebleeds. These effects are usually mild and should not cause alarm. However, if they persist or worsen, it is advisable to consult your healthcare provider. Bleeding is another side effect that occurs in a small percentage of users. While often mild, it should be monitored.

In addition to these, some users might experience diarrhea, a slower heart rate, sleep apnea, or skin rash. While these are generally uncommon, it's important to pay attention to their severity and consult a healthcare professional if they cause concern.

More serious side effects, though rare, require immediate medical attention. These include severe bleeding, which may manifest as blood in the urine, vomiting or coughing up blood, bloody or dark stools, and severe stomach pain. Other serious symptoms to watch for include a fast, slow, or irregular heartbeat, fainting, confusion, trouble speaking, vision changes, and signs of blood clotting issues like red or purple pinpoint spots on the skin. Additionally, although rare, allergic reactions such as rash, itching, swelling, severe dizziness, or trouble breathing should prompt urgent medical care.

It is essential to be vigilant about these side effects and seek medical advice if you notice any unusual symptoms. Always prioritize your health and safety when experiencing any adverse effects from this medication.

Brilinta (ticagrelor) can interact with various medications, which may impact its effectiveness or increase the risk of side effects. It's important to inform your doctor and pharmacist about all medications and supplements you are taking, including prescriptions, over-the-counter drugs, vitamins, and herbal supplements.

Some drugs should not be used with Brilinta, such as Defibrotide and Itraconazole, as they may cause significant interactions. Your doctor may need to adjust your treatment if these are part of your medication regimen.

There are other medications with which Brilinta is usually not recommended unless necessary. If prescribed together, your doctor might alter the dosage or frequency of use. These include, but are not limited to, Abametapir, Apixaban, Clopidogrel, Dabigatran, Ibuprofen, Ketoconazole, Naproxen, and Ritonavir.

Additionally, combining Brilinta with certain medications may heighten the risk of side effects, although the combination might be necessary for your treatment. In such cases, your doctor will monitor and adjust your treatment as needed. Examples include Digoxin and Simvastatin.

Also, Brilinta may interfere with specific lab tests, such as platelet function tests, potentially leading to inaccurate results. Ensure all healthcare providers and lab technicians are aware you are taking this medication. If you're on low-dose Aspirin to prevent heart issues, continue as directed by your doctor. Always consult your doctor or pharmacist for more detailed information.