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When using this medication, it is important to be aware of potential interactions and precautions. Here are some key points to consider:

• Drug Interactions: This medication may interact with certain drugs such as digoxin and phosphate binders. Additionally, calcium can reduce the absorption of other medications, including tetracycline antibiotics (e.g., doxycycline, minocycline), bisphosphonates (e.g., alendronate), estramustine, levothyroxine, and quinolone antibiotics (e.g., ciprofloxacin, levofloxacin). To prevent this, ensure there is a sufficient gap between the administration of these medications and your calcium/vitamin D doses. Consult your healthcare provider to determine the appropriate interval and establish a suitable dosing schedule.

• Vitamin D Absorption: The absorption of vitamin D can be hindered by specific medications such as bile acid sequestrants (e.g., cholestyramine, colestipol), mineral oil, and orlistat. It is advisable to space these medications apart from vitamin D doses as much as possible.

• Product Labels: Carefully check the labels of all prescription, non-prescription, and herbal products, including antacids, laxatives, and vitamins, as they may contain calcium, phosphate, or vitamin D. Your pharmacist can provide guidance on the safe use of these products.

• Avoiding Duplication: Since vitamin D is very similar to calcitriol, avoid taking medications containing calcitriol while using vitamin D.

• Laboratory Interference: This medication may affect the results of certain laboratory tests, such as cholesterol tests, leading to inaccurate results. Inform lab personnel and all your healthcare providers about your use of this product to ensure accurate test outcomes.

Adhering to these guidelines can help you use this medication safely and effectively. Always follow the advice of your healthcare provider.

Common side effects:

• Constipation
• Upset stomach

Less common but important to monitor:

• Nausea
• Vomiting
• Loss of appetite
• Unusual weight loss
• Changes in mood or mental state
• Altered urine output (suggesting kidney issues)
• Bone or muscle pain
• Headaches
• Increased thirst or urination
• Weakness
• Fatigue
• Rapid or pounding heartbeat

Serious side effects:

• Severe allergic reactions (rash, itching or swelling, particularly on the face, tongue, or throat, severe dizziness, difficulty breathing)

Interactions with high risk of serious adverse effects and should be avoided:

• Calcitriol

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Digoxin
• phosphate binders
• tetracycline antibiotics (e.g., doxycycline, Minocycline)
• bisphosphonates (e.g., Alendronate)
• estramustine
• Levothyroxine
• quinolone antibiotics (e.g., Ciprofloxacin, Levofloxacin)
• bile acid sequestrants (e.g., Cholestyramine, Colestipol)
• Mineral Oil
• Orlistat