Cilostazol

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Cilostazol is prescribed to alleviate symptoms associated with intermittent claudication, a condition characterized by poor blood flow in the legs, leading to pain, numbness, and tingling during activities such as walking or exercise. This medication helps improve your capacity to walk longer distances without discomfort. Cilostazol functions as a phosphodiesterase III inhibitor, which prevents blood cells called platelets from clumping together and forming clots. Additionally, it acts as a vasodilator, widening blood vessels in the legs to enhance blood flow and increase oxygen delivery to the muscles. As a result, it decreases muscle pain and cramps, promoting smoother blood circulation throughout the body.
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100MG, Cilostazol (30 Tablets)

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CVS

$20.19

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Rite Aid

$7.64

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Albertsons

$12.05

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Walgreens

$12.23

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CVS

$20.19

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Cilostazol dosage forms

The average cost for 30 Tablets of Cilostazol at 50MG is $8 with a free coupon. This is 18.78% off the average retail price of $42.6
DosageQuantityPrice fromPer unit
50MG30 Tablets$8$0.27
100MG30 Tablets$8$0.27

Cilostazol Warnings

When considering the use of cilostazol, it's important to be aware of several key safety warnings and potential risks. This medication may not be suitable for everyone, particularly those with specific pre-existing conditions. Below are important considerations:

  • Heart Failure Risk: Cilostazol is not recommended for individuals with heart failure, as it may exacerbate the condition and increase the risk of serious complications, including death. Inform your healthcare provider of any history of heart failure or heart-related issues prior to starting this medication.

  • Increased Heart Rate: Patients may experience a rapid heart rate when taking cilostazol, which can be problematic for those with existing heart conditions, such as a history of heart attack or chest pain. It is crucial to discuss your medical history with your healthcare provider before beginning treatment. Report any new symptoms like heart murmurs or irregular heartbeats immediately.

  • Blood Cell Count Changes: Cilostazol may lead to decreased levels of white blood cells and platelets, potentially affecting other blood tests. Regular monitoring of blood counts by your healthcare provider is advised to ensure safe continuation of the medication.

  • Increased Bleeding Risk: The medication can elevate the risk of bleeding by interfering with the blood's ability to clot. This is particularly concerning for those with bleeding disorders. It is important to inform your healthcare provider of any such conditions and to monitor for unusual symptoms, such as unexplained bruising, prolonged bleeding, red or dark urine, or coughing up blood.

Always consult with your healthcare provider to review your medical history and discuss any concerns before starting cilostazol. If you experience any adverse effects or have questions regarding the medication, seek medical advice promptly.

Cilostazol Side Effects

Common side effects:

  • headaches
  • diarrhea
  • runny nose

Less common but important to monitor:

  • dizziness
  • abnormal stools

Serious side effects:

  • swelling of the hands or feet
  • easy bruising or bleeding
  • black or bloody stools
  • vomiting resembling coffee grounds
  • signs of infection (persistent sore throat or fever)
  • chest pain
  • fainting
  • fast or irregular heartbeat
  • severe dizziness
  • vision changes
  • sudden weakness on one side of the body
  • allergic reaction (rash, itching, swelling of the face, tongue, or throat, severe dizziness, trouble breathing)

Cilostazol Interactions

Interactions with high risk of serious adverse effects and should be avoided:

  • Defibrotide

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

Cilostazol FAQs
What class of drugs is cilostazol?

Cilostazol is classified as a phosphodiesterase III inhibitor.

Cilostazol should not be taken with certain medications due to potential interactions. These include:1. Strong CYP3A4 inhibitors such as ketoconazole, itraconazole, and clarithromycin, as they can increase cilostazol levels in the blood.2. Strong CYP2C19 inhibitors like omeprazole, which can also elevate cilostazol levels.3. Anticoagulants and antiplatelet drugs such as warfarin and aspirin, as they may increase the risk of bleeding.4. Other medications that affect heart rhythm, as cilostazol can have cardiovascular effects.It is important for patients to consult their healthcare provider before starting or stopping any medications while on cilostazol.

Cilostazol and aspirin are not the same. Cilostazol is a medication primarily used to treat intermittent claudication, a condition that causes pain in the legs due to poor circulation. It works by improving blood flow and reducing muscle pain. Aspirin, on the other hand, is an antiplatelet agent commonly used to reduce pain, fever, inflammation, and to prevent blood clots. While both can affect blood flow, they have different mechanisms of action and are used for different medical purposes.

Cilostazol carries a black box warning due to its contraindication in patients with heart failure of any severity. This is because the drug has been shown to increase mortality in patients with heart failure. Therefore, it should not be used in individuals with this condition.

Aspirin and cilostazol are both medications used to manage different cardiovascular conditions, but they have distinct mechanisms of action and uses. Aspirin is an antiplatelet agent that works by inhibiting the aggregation of platelets, thereby reducing the risk of blood clots. It is commonly used for the prevention of heart attacks and strokes.Cilostazol, on the other hand, is a phosphodiesterase III inhibitor that works by dilating blood vessels and inhibiting platelet aggregation. It is primarily used to improve symptoms of intermittent claudication, a condition characterized by pain in the legs due to inadequate blood flow during exercise.In summary, while both medications can affect platelet function, aspirin is mainly used for its antiplatelet effects in preventing cardiovascular events, whereas cilostazol is used to improve blood flow in peripheral artery disease.