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Oxycodone/acetaminophen, a pain-relieving medication, carries significant safety warnings due to its potential for addiction and severe side effects. It is crucial for patients and healthcare providers to understand these risks and adhere strictly to prescribed guidelines.

• Risk of Abuse and Addiction: This medication can be habit-forming, leading to misuse, overdose, and even death. It is important to follow your healthcare provider's instructions closely, taking the smallest effective dose for the shortest duration possible.

• Breathing Problems: Severe, potentially fatal respiratory depression can occur, especially at the start of treatment or with dose increases. Avoid combining this drug with alcohol or other sedatives, which can exacerbate this risk. Carry naloxone as a precaution against opioid overdose and ensure those around you know its use.

• Liver Damage from Acetaminophen: Exceeding the maximum daily dose of acetaminophen (4 grams for adults) can lead to serious liver damage. Avoid using other medications containing acetaminophen without medical consultation, and refrain from alcohol consumption.

• Pregnancy and Newborn Risk: Use during pregnancy should be limited to when absolutely necessary, as it may cause birth defects or withdrawal symptoms in newborns. Discuss the risks and benefits with your healthcare provider.

• Interactions with Other Medications: Many drugs can interact with oxycodone/acetaminophen, altering its effectiveness or increasing side effects. Inform your healthcare provider of all medications you are taking.

• Emergency Overdose Actions: Overdose symptoms include extreme drowsiness, slow heartbeat, and difficulty breathing. Immediate medical attention and naloxone administration are critical.

• Safe Storage: Keep the medication secure to prevent theft or misuse, and ensure it is out of reach of children and pets to avoid accidental ingestion.

• Allergic Reactions: Be aware of potential severe allergic reactions, including skin rashes or anaphylaxis. Discontinue use and seek medical help if these occur.

• Physical Dependence and Withdrawal: Long-term use can lead to dependence, and abrupt cessation might cause withdrawal symptoms. Consult your healthcare provider before making any changes to your dosage.

• Other Health Risks: The medication may cause low blood pressure, adrenal insufficiency, or seizures in susceptible individuals. Report any concerning symptoms to your healthcare provider promptly.

Consult with your healthcare provider to address any concerns or questions about using oxycodone/acetaminophen, and adhere to their guidance to minimize risks.

When taking this medication, it's common to experience mild side effects such as nausea, vomiting, constipation, dizziness, lightheadedness, drowsiness, and itching. These effects often improve over time. To help manage constipation, consider increasing dietary fiber, drinking more water, and staying active. Rising slowly from sitting or lying down can reduce dizziness and lightheadedness.

There are other side effects that may occur, including headache, sweating, heartburn, bloating, changes in taste, stomach or muscle pain, and fluctuations in blood pressure or heartbeat. While these are generally not serious, consult your healthcare provider if they persist or become concerning.

Serious side effects, though rare, require immediate medical attention. These include dangerously slow breathing, symptoms of an overdose such as unresponsiveness and slow heartbeat, signs of opioid withdrawal like anxiety and restlessness, and severe allergic reactions characterized by rash, blistering skin, or difficulty breathing.

Seek urgent medical care if you experience severe symptoms such as fainting, seizures, severe drowsiness, or difficulty waking up. An allergic reaction is uncommon, but watch for symptoms like rash, itching, swelling, or trouble breathing. If you notice any side effects not mentioned here, contact your healthcare provider.

When taking Percocet (Oxycodone/Acetaminophen), it's important to be aware of its potential interactions with other medications or supplements. Inform your doctor or pharmacist about any other substances you're using, whether they're prescription, over-the-counter, vitamins, or herbal supplements.

Certain medications should not be combined with Percocet due to the risk of severe interactions. These include nalmefene, Naltrexone, and safinamide. Your doctor might decide against using these medications together or adjust your treatment plan.

There are other medications that are generally not recommended to be taken with Percocet, but exceptions might be made based on your specific circumstances. In such cases, your healthcare provider may adjust the dosage or frequency. Some of these medications include abiraterone acetate, Alprazolam, Buprenorphine, Carisoprodol, Carbamazepine, Cetirizine, and Erythromycin, among many others. Combining these can increase the risk of side effects like drowsiness or breathing difficulties.

Additionally, certain medications can alter the way Percocet is processed in your body, which might affect its effectiveness. These include azole antifungals like Ketoconazole, macrolide antibiotics such as erythromycin, and antiretroviral drugs like Ritonavir.

Always check the labels of any other products you're taking, such as allergy or cough-and-cold medications, as they might contain ingredients that could increase drowsiness. If you're using any of these products, consult your pharmacist to ensure they're safe to use with Percocet.

Lastly, Percocet may interfere with certain laboratory tests, potentially leading to inaccurate results, so ensure that all healthcare providers are aware that you are taking this medication.