Hydrocodone-acetaminophen Coupons & Savings Card – Discount Prices from $32.58

Hydrocodone/acetaminophen, known as Norco, poses several significant safety concerns and risks that must be carefully considered before use. Below are key points to ensure safe administration and awareness of possible complications:

• Risk of Abuse and Addiction: This medication is a controlled substance with potential for misuse and addiction, which can result in overdose or death. It is crucial to follow the prescribed dosage and schedule closely. Individuals with a personal or familial history of substance use or mental health disorders may have a heightened risk.

• Respiratory Depression: Hydrocodone/acetaminophen can cause dangerously slow breathing, especially when starting treatment or increasing the dose. Combining it with alcohol or other sedatives can amplify this risk. Immediate medical attention is necessary if symptoms such as shallow breathing, unusual lightheadedness, or difficulty waking occur.

• Opioid Overdose: Taking more than the prescribed dose can lead to an overdose, which is life-threatening. Keep the medication secure to prevent accidental ingestion, particularly by children or pets. Consider having naloxone on hand as a precaution against opioid overdose.

• Liver Damage: Acetaminophen is associated with a risk of severe liver damage, especially when exceeding 4000 milligrams daily, consuming alcohol, or taking other acetaminophen-containing products. Monitor for symptoms of overdose, such as nausea, abdominal pain, and jaundice, and seek prompt medical help.

• Pregnancy and Newborn Risks: Usage during pregnancy should be limited and only when absolutely necessary, as it may cause birth defects or withdrawal symptoms in the newborn. Pregnant individuals should discuss potential risks with their healthcare provider.

• Drug Interactions: Hydrocodone/acetaminophen can interact with various medications, potentially altering its effectiveness or increasing side effects. Inform your healthcare provider about all medications you are taking to avoid harmful interactions.

• Allergic Reactions and Skin Issues: Severe allergic reactions, including anaphylaxis, and rare skin reactions might occur. Seek immediate medical attention if you experience swelling, difficulty breathing, or changes in skin condition.

• Physical Dependence and Withdrawal: Long-term use can lead to physical dependence and withdrawal symptoms upon abrupt cessation. Gradual dose reduction is advised to mitigate withdrawal effects.

• Low Blood Pressure and Adrenal Hormone Levels: The medication may cause a drop in blood pressure and low adrenal hormone levels, leading to dizziness or fainting. Stand up slowly from sitting or lying positions to prevent falls.

• Seizures: Those with a history of seizures should use caution, as hydrocodone can increase seizure frequency. Seek emergency assistance if a seizure occurs.

Contraindications: Avoid using this medication if you have severe breathing issues, severe asthma, gastrointestinal blockages, or allergies to hydrocodone or acetaminophen.

Adhering to these guidelines and consulting healthcare professionals as needed will help manage the risks associated with hydrocodone/acetaminophen use.

Common side effects:

• nausea
• vomiting
• constipation
• dizziness
• sleepiness
• itching

Less common but important to monitor:

• headaches
• tiredness
• "brain fog"
• stomach pain
• changes in blood pressure

Serious side effects:

• slowed breathing
• difficulty breathing
• bluish-colored lips or extremities
• extreme sleepiness
• slow heartbeat
• yellowing skin or eyes
• anxiety
• restlessness
• chills
• severe allergic reactions
• rash
• hives

Interactions with high risk of serious adverse effects and should be avoided:

• Nalmefene
• Naltrexone
• Safinamide

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Butorphanol
• Nalbuphine
• Pentazocine
• Samidorphan
• Alcohol
• Marijuana (cannabis)
• Alprazolam
• Lorazepam
• Zolpidem
• Carisoprodol
• Cyclobenzaprine
• Cetirizine
• Diphenhydramine
• Azole antifungals (such as ketoconazole)
• Macrolide antibiotics (such as erythromycin)
• Levoketoconazole
• Mifepristone
• HIV medications (such as tipranavir)
• Rifamycins (such as rifabutin, rifampin)
• Ritonavir
• Carbamazepine
• Phenytoin