Hydrocodone-ibuprofen Coupons & Savings Card – Discount Prices from $133.92

Hydrocodone/ibuprofen is associated with several safety concerns and precautions due to its composition. Below is a summary of important safety information for users and healthcare providers:

• Risk of Addiction and Misuse: Hydrocodone/ibuprofen contains hydrocodone, an opioid, which poses a risk of addiction and misuse even at prescribed doses. Addiction can lead to overdoses, which may be life-threatening. To reduce this risk, healthcare providers should prescribe the smallest effective dose for the shortest duration. Individuals with a personal or family history of substance abuse or mental health disorders such as depression are at higher risk.

• Respiratory Depression: Opioids like hydrocodone can cause severe, possibly fatal, breathing problems. This risk is heightened at the start of treatment or after a dose increase. Using alcohol or other medications that cause drowsiness or slow breathing, such as benzodiazepines, can exacerbate this effect. Seek immediate medical attention if you experience difficulty breathing, slow or shallow breathing, or bluish lips, fingers, or toes.

• Overdose Risk: Accidental overdose is a serious concern, particularly if the drug is taken by children or non-prescribed individuals. Symptoms of overdose include slowed breathing, slow heartbeat, extreme drowsiness, cold or clammy skin, and unresponsiveness. Call 911 immediately if an overdose is suspected. Naloxone may be recommended by your provider as an emergency treatment for opioid overdose.

• Cardiovascular Risks: Hydrocodone/ibuprofen can increase the risk of heart attack, stroke, and blood clots. Those with heart disease, recent heart attacks, or those undergoing heart surgery should avoid this medication. Take the lowest effective dose for the shortest period possible to mitigate these risks.

• Gastrointestinal Risks: Ibuprofen, a component of this medication, can cause serious, sometimes fatal, stomach bleeding and ulcers. This risk is higher in older adults and those with a history of stomach issues. Combining with other medications that cause bleeding, such as anticoagulants or other NSAIDs, increases this risk.

• Pregnancy and Newborn Risks: Prolonged use during pregnancy can lead to neonatal opioid withdrawal syndrome (NOWS) in newborns, which can be life-threatening if untreated. Pregnant individuals should consult their healthcare provider about the risks and benefits of using this medication.

• Hypotension: The medication can cause dangerously low blood pressure, especially when standing up, leading to dizziness or fainting. Stand up slowly from sitting or lying positions to prevent falls.

• Kidney and Liver Concerns: Long-term use can damage kidneys and affect liver function. Report any changes in urination or symptoms of liver problems, such as nausea or jaundice, to your healthcare provider.

• Interactions with Other Medications: Certain drugs can affect how hydrocodone/ibuprofen is processed in the body, altering its effectiveness and increasing side effects. Inform your healthcare provider of all medications you are taking.

• Asthma and Allergic Reactions: Those with asthma or a history of allergic reactions to NSAIDs should use caution. Serious allergic reactions and skin reactions can occur, and immediate medical attention is required if symptoms arise.

• Contraindications: This medication should not be used in individuals with severe asthma, recent heart bypass surgery, certain gastrointestinal conditions, or allergies to opioids or NSAIDs. Always consult with your healthcare provider to ensure this medication is safe for you.

Common side effects:

• headaches
• constipation
• nausea
• sleepiness
• dizziness

• indigestion

  Less common but important to monitor:

• stomach pain
• vomiting
• diarrhea
• gas
• dry mouth
• anxiety
• nervousness
• weakness
• trouble sleeping
• body swelling
• itchiness
• sweating

• infections

  Serious side effects:

• slowed breathing
• signs of overdose
• heart-related problems
• heart attacks
• heart failure
• strokes
• stomach or intestinal bleeding
• opioid withdrawal
• severe allergic reactions
• severe skin conditions
• seizures
• signs of liver damage

Interactions with high risk of serious adverse effects and should be avoided:

• Ketorolac
• Nalmefene
• Naltrexone
• Safinamide
• Warfarin
• Clopidogrel

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Amitriptyline
• Carbamazepine
• Erythromycin
• Ritonavir
• Aspirin
• Naproxen
• Alprazolam
• Cyclobenzaprine
• Alcohol