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generic Lucemyra

Lofexidine, marketed under the brand name Lucemyra, is a prescription medication designed to alleviate withdrawal symptoms in adults discontinuing opioid use. It is particularly effective in reducing symptoms like chills, stomach cramps, and body aches. As an alpha-2 adrenergic receptor agonist, Lofexidine works by decreasing norepinephrine levels in the brain, a chemical known to trigger withdrawal symptoms. Additionally, it helps relax blood vessels, lowering blood pressure and heart rate to calm the body. Lofexidine is typically taken orally four times a day, with doses spaced 5 to 6 hours apart. While it can be a valuable part of a comprehensive treatment plan that includes counseling and lifestyle changes, users may experience side effects such as dizziness and difficulty sleeping. Always consult with a healthcare professional before beginning any new medication.
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0.18MG, Lofexidine (30 Tablets)

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CVS

$242.79

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$134.58

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$140.83

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$378.07

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$660.40

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Lofexidine savings card

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$242.79

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Lofexidine dosage forms

The average cost for 30 Tablets of Lofexidine (generic Lucemyra) at 0.18MG is $214.25 with a free coupon. This is 16.26% off the average retail price of $1317.26
DosageQuantityPrice fromPer unit
0.18MG30 Tablets$214.25$7.14

Lofexidine Warnings

This medication, Lucemyra (lofexidine), has several important safety warnings that should be reviewed carefully. Consult your healthcare provider for any concerns or questions regarding these risks.

  • Low Blood Pressure and Heart Rate Risks: Lucemyra can cause a decrease in blood pressure and heart rate, which may result in fainting. Inform your healthcare provider about your medical history and all medications you are currently taking to assess the safety of using Lucemyra. Special attention should be paid to those with dehydration, overheating, a history of heart problems, recent heart attacks, strokes, kidney failure, or those taking medications that lower blood pressure or heart rate.

  • Risk of Life-Threatening Heart Rhythms: The medication may lead to QT prolongation, a condition that affects the heart's rhythm and can be life-threatening. Individuals with heart failure, slow heart rhythms, kidney or liver issues, low magnesium or potassium levels, or those taking medications like methadone that can cause abnormal heart rhythms should exercise caution.

  • Excessive Sleepiness: Lucemyra can cause significant drowsiness and impair cognitive functions. This effect is amplified by alcohol or medications that induce drowsiness or slow bodily functions, such as benzodiazepines. Avoid driving or operating machinery until you understand how the medication affects you. If you experience symptoms like slurred speech, lightheadedness, confusion, or excessive drowsiness, seek medical help immediately.

  • Increased Opioid Overdose Risk: This medication is intended only for managing opioid withdrawal symptoms and is not approved for treating opioid addiction. Use caution if you have an opioid use disorder.

  • Withdrawal Side Effects: Abrupt discontinuation of Lucemyra can result in increased blood pressure and other withdrawal symptoms such as insomnia, anxiety, chills, sweating, and limb pain. Consult with your healthcare provider before stopping the medication; they can guide you in tapering off the dose gradually to minimize withdrawal effects.

These warnings are crucial for ensuring safe and effective use of Lucemyra. Always communicate openly with your healthcare provider about any concerns or unusual symptoms.

Lofexidine Side Effects

Common side effects:

  • Excessive sleepiness
  • Dizziness
  • Lightheadedness when standing up
  • Trouble sleeping
  • Dry mouth
  • Slow heart rate
  • Low blood pressure

Less common but important to monitor:

  • Ringing in the ears
  • Feeling faint

Serious side effects:

  • Abnormal heart rhythms
  • Chest pounding
  • Irregular heartbeat
  • Chest pain
  • Shortness of breath
  • Trouble breathing
  • Shallow breathing
  • Extreme sleepiness
  • Blue skin
  • Severe allergic reaction
  • Rash
  • Itching or swelling of the face, tongue, or throat
  • Severe dizziness

Lofexidine Interactions

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

  • Alcohol
  • Marijuana (cannabis)
  • Alprazolam
  • Lorazepam
  • Zolpidem
  • Carisoprodol
  • Cyclobenzaprine
  • Cetirizine
  • Diphenhydramine
Lofexidine FAQs
Is lofexidine the same as clonidine?

Lofexidine and clonidine are not the same, although they are both medications used to manage withdrawal symptoms. They are both alpha-2 adrenergic agonists, but lofexidine is specifically approved for the treatment of opioid withdrawal symptoms, while clonidine is used for a variety of conditions, including hypertension and withdrawal symptoms. They have similar mechanisms of action but are distinct medications with different approved uses and dosing guidelines.

Lofexidine is used to help manage withdrawal symptoms in individuals who are discontinuing opioid use. It is not an opioid itself but works by reducing the severity of withdrawal symptoms, making the process more tolerable.

Lofexidine is not classified as a controlled substance. It is a medication used to manage withdrawal symptoms in individuals undergoing opioid detoxification.

The effectiveness of Lucemyra (lofexidine) versus Suboxone (buprenorphine/naloxone) depends on the specific needs and circumstances of the individual. Lucemyra is used to manage withdrawal symptoms in individuals discontinuing opioids, while Suboxone is used for opioid dependence treatment and maintenance therapy. A healthcare provider can determine the most appropriate treatment based on the individual's medical history, the severity of dependence, and treatment goals.

Lucemyra (lofexidine) is an FDA-approved medication used to manage withdrawal symptoms in individuals discontinuing opioid use. Clinical studies have shown that it can be effective in reducing the severity of withdrawal symptoms. However, its effectiveness can vary from person to person, and it is typically used as part of a comprehensive treatment plan that includes other supportive measures. It is important for individuals to consult with their healthcare provider to determine if Lucemyra is appropriate for their specific situation.