Buprenorphine

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buprenorphine

Buprenorphine patches, commonly known as Butrans, are prescribed for the management of severe, long-lasting pain that other treatments have failed to alleviate. These patches belong to the opioid analgesic class and specifically function as a partial agonist, targeting specific opioid receptors in the brain to alter pain perception and reduce pain levels. Intended for patients already accustomed to moderate opioid use, these patches are available in various strengths, and dosage is determined by the severity of pain and previous opioid usage. The patches are applied to the skin once a week. It is crucial to avoid using this medication for mild or temporary pain, and it should not be used on an "as needed" basis. Potential side effects include nausea, dizziness, and headaches. Always consult a healthcare professional for advice tailored to your personal health needs before using this medication.
Our Butrans coupons are free to use. You can print the coupon, email it to yourself, or receive the Butrans coupon via text message. To get your free discount, show the pharmacist your Butrans savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Butrans prices will update based on your prescription needs. Above our Butrans coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Butrans savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.

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10MCG/HR, Buprenorphine (4 Patch Weeklies)

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CVS

$58.78

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Walgreens

$127.86

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Rite Aid

$131.85

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Albertsons

$258.40

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CVS

$58.78

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Butrans dosage forms

The average cost for 4 Patch Weeklies of Butrans (buprenorphine) at 5MCG/HR is $53.17 with a free coupon. This is 11.58% off the average retail price of $459.08
DosageQuantityPrice fromPer unit
5MCG/HR4 Patch Weeklies$53.17$13.29
10MCG/HR4 Patch Weeklies$58.8$14.7
20MCG/HR4 Patch Weeklies$94.29$23.57
15MCG/HR4 Patch Weeklies$76.5$19.13
7.5MCG/HR1 Patch Weekly$28.2$28.2

Butrans Warnings

Buprenorphine patches (Butrans) require careful consideration due to potential risks and safety concerns. It is crucial to follow medical guidance precisely and be aware of the following safety information:

  • Risk of Addiction and Misuse: Buprenorphine is a Schedule III controlled substance with a risk of addiction and misuse, which can lead to overdose or death. Avoid placing the patch in the mouth, chewing, or swallowing it. Discuss with your healthcare provider about having naloxone on hand to counteract possible opioid overdoses.

  • Severe Respiratory Depression: This medication can cause dangerously slow breathing, especially when starting treatment or increasing the dose. This risk is heightened by alcohol, other sedatives, or existing respiratory conditions. Seek emergency care if symptoms like slow/shallow breathing, extreme sleepiness, or difficulty waking occur.

  • Overdose Precautions: Use the medication exactly as prescribed to prevent overdose. Store it securely away from children, pets, and unauthorized users. Signs of overdose include extreme drowsiness, slow heartbeat, and cold, clammy skin. Keep naloxone accessible and educate family members on its use.

  • Cognitive and Motor Impairment: Buprenorphine can cause drowsiness and impair thinking and reaction times. Avoid alcohol and other sedative medications. Assess how the medication affects you before engaging in tasks that require alertness, such as driving.

  • Pregnancy and Newborn Risks: Using buprenorphine during pregnancy may lead to dependency in the unborn child, causing withdrawal symptoms after birth. Use the lowest effective dose for the shortest duration and inform healthcare providers if you are pregnant or plan to become pregnant.

  • Temperature Sensitivity: Exposure to heat (e.g., from fever, exercise, or external sources like heating pads) can increase drug release from the patch, leading to adverse effects. Avoid exposing the patch to high temperatures.

  • Adrenal Insufficiency: Prolonged use may result in low adrenal hormone levels. Report symptoms like fatigue, nausea, or loss of appetite to your healthcare provider.

  • Blood Pressure and Liver Concerns: Buprenorphine can cause low blood pressure and liver damage. Regular monitoring and communication with your healthcare provider are important, especially if you have a history of liver problems or take medications that affect blood pressure.

  • Withdrawal Symptoms: Sudden discontinuation can lead to withdrawal symptoms. Consult your healthcare provider to taper the dose safely.

  • Seizure Risk: If you have a history of seizures, be cautious as buprenorphine may increase seizure frequency.

  • Heart Rhythm Issues: Buprenorphine can cause QT prolongation, affecting heart rhythm. Discuss your complete medical history with your healthcare provider to assess this risk.

This medication is contraindicated in individuals with severe respiratory depression, asthma, gastrointestinal blockages, or previous allergic reactions to buprenorphine. Always consult with your healthcare provider for personalized advice and adhere strictly to the prescribed regimen to minimize risks.

Butrans Side Effects

When using this medication, some individuals may experience common side effects that are generally mild and manageable. These include nausea, itching or redness at the application site, dizziness, headache, drowsiness, constipation, vomiting, dry mouth, and upset stomach. It's important to note that these side effects often improve as your body adjusts to the medication. Staying hydrated, consuming fiber, and regular exercise can help prevent constipation. To minimize dizziness, rise slowly from sitting or lying positions.

In some cases, other side effects such as tiredness, increased sweating, and swelling in the arms, legs, or ankles may occur. If these or any symptoms persist or worsen, it is advisable to consult your healthcare provider for guidance.

More serious side effects, though rare, require immediate medical attention. These include dangerously slow breathing, signs of an overdose such as extreme sleepiness and slow heartbeat, and symptoms of opioid withdrawal like anxiety or severe skin reactions. Additionally, any signs of heart rhythm problems or serious allergic reactions, such as rash, hives, or difficulty breathing, warrant urgent care.

A rare but serious risk includes liver damage, indicated by persistent nausea or vomiting, dark urine, loss of appetite, yellowing of the skin or eyes, and severe abdominal pain. If you experience any of these serious side effects, seek medical help right away. Always report any unexpected side effects to your healthcare provider.

Butrans Interactions

Some products that may interact with this drug include: certain pain medications (mixed opioid agonist-antagonists such as butorphanol, nalbuphine, pentazocine), naltrexone, samidorphan. The risk of serious side effects (such as slow/shallow breathing, severe drowsiness/dizziness) may be increased if this medication is used with other products that may also cause drowsiness or breathing problems. Tell your doctor or pharmacist if you are taking other products such as other opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or antihistamines (such as cetirizine, diphenhydramine). Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely. This medication may interfere with certain lab tests (such as amylase/lipase levels), possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.
Butrans FAQs
What type of opioid is Butrans?

Butrans is a transdermal patch that contains buprenorphine, which is a partial opioid agonist.

Butrans 5 and morphine are not equivalent. Butrans contains buprenorphine, which is a partial opioid agonist, while morphine is a full opioid agonist. They have different potencies and pharmacological profiles. The equivalence between these medications would depend on specific dosing and individual patient factors, and should be determined by a healthcare professional.

The most common side effect of transdermal patches is skin irritation at the site of application. This can include redness, itching, or a rash.

Buprenorphine and oxycodone are both opioids, but they have different potencies and mechanisms of action. Buprenorphine is a partial agonist at the mu-opioid receptor, while oxycodone is a full agonist. This means that buprenorphine generally has a ceiling effect, limiting its maximum effect, whereas oxycodone does not. Therefore, oxycodone is typically considered to be stronger in terms of its potential for pain relief and euphoria. However, the effectiveness and strength can vary based on individual patient factors and specific clinical situations.

Butrans is classified as an opioid analgesic. It is specifically a transdermal patch formulation of buprenorphine, which is used for managing moderate to severe chronic pain.