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Promethazine-dm

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This combination medication is used to temporarily treat runny nose, coughing, and sneezing caused by the common cold, allergies, hay fever, and other breathing illnesses. Promethazine is a phenothiazine that works like an antihistamine. It blocks the effects of a certain natural substance (histamine), which causes allergy symptoms. It also has a drying effect. Dextromethorphan belongs to a class of drugs known as cough suppressants. It acts on a part of the brain (cough center) to reduce the need to cough. This product is usually not used for ongoing cough from smoking or long-term breathing problems (such as chronic bronchitis, emphysema) unless directed by your doctor. Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Ask your doctor or pharmacist for more details about using your product safely. These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Do not use this product to make a child sleepy. Do not give other cough-and-cold medication that might contain the same or similar ingredients (see also Drug Interactions section). Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray).
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118ML of 6.25-15MG/5ML, Promethazine-dm (1 Bottle)

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Warnings

Promethazine should not be used by children younger than 2 years since it might cause serious (possibly fatal) slow/shallow breathing. This problem has occurred even with normal doses in this age group. The lowest effective dosage should be used, and other drugs that affect breathing should be avoided. Get medical help right away in the unlikely event that slow/shallow breathing occurs. Promethazine should not be used by children with liver disease (including possible Reyes syndrome).

Promethazine-dm Side Effects

Drowsiness, dizziness, blurred vision, nausea, constipation, or dry mouth may occur. If any of these effects last or get worse, notify your doctor or pharmacist promptly. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. If you are very sleepy or have difficulty waking up after using this medication, stop taking this medication and talk to your doctor or pharmacist right away. Your dosage may need to be lower. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. Tell your doctor right away if you have any serious side effects, including: decreased coordination, difficulty urinating, shaking (tremor), mental/mood changes (such as nervousness, excitement, irritability, confusion, hallucinations), abnormal/uncontrolled movements (such as fixed upward stare, neck twisting, tongue movements), slow heartbeat, fainting. Get medical help right away if you have any very serious side effects, including: slow/shallow breathing, seizures. This medication may rarely cause a very serious condition called neuroleptic malignant syndrome (NMS). Get medical help right away if you have any of the following symptoms: fever, muscle stiffness/pain/tenderness/weakness, severe tiredness, severe confusion, sweating, fast/irregular heartbeat, dark urine, signs of kidney problems (such as change in the amount of urine). A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. In the US - Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

Interactions

Some products that may interact with this drug include: diphenhydramine or other antihistamines applied to the skin (such as anti-itch cream, ointment, spray), metoclopramide, rolapitant. Taking certain MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking isocarboxazid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, or tranylcypromine during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Ask your doctor when to start or stop taking this medication. The risk of serious side effects (such as slow/shallow breathing, severe drowsiness/dizziness) may be increased if this medication is taken with other products that may also cause drowsiness or breathing problems. Tell your doctor or pharmacist if you are taking other products such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or other antihistamines (such as cetirizine, diphenhydramine). Check the labels on all your medicines (such as allergy or cough-and-cold products) because they may contain ingredients that cause drowsiness. Ask your pharmacist about using those products safely. Dextromethorphan is available in both prescription and nonprescription products. Check the labels of all your medications to make sure you are not taking more than one product containing dextromethorphan. This medication may interfere with certain lab tests (such as urine pregnancy tests, skin allergy tests), possibly causing false test results. Make sure lab personnel and all your doctors know you use this drug.
Promethazine-dm FAQs
Does promethazine DM contain codeine?

Promethazine DM does not contain codeine. It is a combination of promethazine, an antihistamine, and dextromethorphan, a cough suppressant.

Yes, promethazine DM can cause drowsiness as a side effect. Promethazine is an antihistamine that has sedative properties, which can lead to feelings of sleepiness. It is important to avoid activities that require alertness, such as driving, until the individual knows how the medication affects them.

Promethazine DM contains both promethazine and dextromethorphan. Promethazine is an antihistamine that helps with allergy symptoms, while dextromethorphan is a cough suppressant. Regular promethazine does not contain dextromethorphan and is used primarily for its antihistamine properties. Therefore, promethazine DM is used to treat both allergy symptoms and cough, whereas regular promethazine is used mainly for allergy symptoms.

DM cough syrup, which typically contains dextromethorphan and guaifenesin, is not known to cause drowsiness. However, individual reactions can vary, and some people might experience mild drowsiness. If drowsiness occurs, it is advisable to avoid driving or operating heavy machinery. If there are concerns about side effects, consulting a healthcare professional is recommended.

Promethazine DM should not be taken by individuals who are allergic to promethazine, dextromethorphan, or any other ingredients in the medication. It is also not recommended for children under the age of 2 due to the risk of severe breathing problems. Additionally, individuals with certain medical conditions such as asthma, chronic obstructive pulmonary disease (COPD), or other breathing disorders should avoid this medication. Those with a history of seizures, liver disease, or a weakened immune system should consult a healthcare provider before use. Pregnant or breastfeeding women should also seek medical advice prior to taking promethazine DM.

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