Mesalamine-cleanser

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mesalamine-cleanser

Mesalamine, also known as 5-aminosalicylic acid, is a medication used to manage inflammatory bowel conditions like ulcerative colitis, proctosigmoiditis, and proctitis. Although it does not cure these conditions, it helps alleviate mild to moderate pain and reduce the frequency of diarrhea and bloody stools by decreasing inflammation and swelling in the colon and rectum. As an aminosalicylate anti-inflammatory drug, Mesalamine works by inhibiting the production of certain natural chemicals that contribute to pain and swelling in the gut. This action helps lessen inflammation in the affected areas. Mesalamine is commonly administered as an enema, typically at bedtime, to maximize its effectiveness. Patients may experience side effects such as stomach cramps, gas, and headache. Mesalamine is available in both brand-name and generic forms, and it is important to consult a healthcare professional for advice tailored to your specific condition and treatment needs.
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4GM, Mesalamine-cleanser (30 Kits)

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$1593.20

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015995

LHKEJ371294

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DR33

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Rowasa dosage forms

The average cost for 30 Kits of Rowasa (mesalamine-cleanser) at 4GM is $1332.19 with a free coupon. This is 86% off the average retail price of $9394.34
DosageQuantityPrice fromPer unit
4GM30 Kits$1332.19$44.41

Rowasa Warnings

This document outlines crucial safety and warning information regarding the use of mesalamine (Rowasa). It is essential to read these points carefully and discuss any concerns with your healthcare provider.

  • Serious Allergic Reactions and Skin Reactions: Mesalamine (Rowasa) can cause severe allergic reactions, which may be life-threatening. Symptoms include difficulty breathing, chest tightness, and swelling of the face, lips, tongue, or eyes. Skin-related allergic reactions may manifest as hives, itchiness, skin pain, redness, blisters, or peeling. Discontinue use immediately and seek emergency medical assistance if you experience any allergic reactions. Those with allergies to mesalamine, sulfites, or a history of asthma should be particularly cautious.

  • Kidney Issues: If you have a history of kidney problems, inform your healthcare provider before starting mesalamine (Rowasa). The drug is processed through the kidneys, and impaired kidney function can lead to medication build-up and increased risk of side effects. Some individuals have experienced serious kidney problems, including failure, while on mesalamine. Discuss potential risks and benefits with your healthcare provider, especially if you have a history of kidney issues, are taking other kidney-affecting medications, or are on sulfasalazine (Azulfidine).

  • Liver Concerns: Those with pre-existing liver conditions may experience worsened liver function while taking mesalamine (Rowasa). Notify your prescriber about any liver conditions prior to starting treatment so they can assess the risks and benefits appropriately.

  • Acute Intolerance Syndrome: Some individuals may not tolerate mesalamine (Rowasa) well, resulting in acute intolerance syndrome. Symptoms include abdominal pain, bloody diarrhea, fever, headache, or rash, which can mimic a UC flare-up. Cease taking the medication and contact your healthcare provider immediately if these symptoms occur.

Contraindications highlight specific conditions under which mesalamine (Rowasa) should not be used due to potential health risks. Consult your healthcare provider if any of the following apply to you:

  • Allergy to sulfites
  • Allergy to salicylates, including aspirin or bismuth subsalicylate (Pepto-Bismol)

This guidance is to ensure safe and effective use of mesalamine (Rowasa).

Rowasa Side Effects

When taking this medication, some individuals might experience mild side effects such as stomach pain, cramps, or discomfort, affecting about 8% of users. Headaches are also common, seen in approximately 7% of patients, while gas and nausea occur in about 6% of cases. Other mild effects include flu-like symptoms, diarrhea, constipation, and stomach bloating. If these symptoms persist or worsen, it is advisable to consult a healthcare provider for guidance.

Additionally, some users have reported experiencing pain, soreness, or burning at the rectum, leg or joint pain, back pain, and hemorrhoids. Other noted side effects include kidney stones, hair loss, dizziness, tiredness or weakness, cold-like symptoms, sore throat, fever, itching, and rash or spots on the skin. Although these symptoms can be bothersome, they are generally not severe.

However, there are rare but serious side effects that require immediate medical attention. These include allergic reactions characterized by itchy, red rashes, shortness of breath, chest tightness, and swelling of the lips, tongue, face, or eyes. Severe skin reactions, such as painful redness, blisters, and a severe rash, also fall into this category. Furthermore, an acute intolerance syndrome may occur, presenting with severe stomach pain, bloody diarrhea, nausea, fever, headache, and rash. If any of these serious side effects occur, it is crucial to seek urgent medical care.

Rowasa Interactions

Mesalamine (Rowasa) can interact with various medications and supplements. It's crucial to inform your doctor and pharmacist about all drugs and supplements you are taking, including prescriptions, over-the-counter items, vitamins, and herbal products. Not all possible interactions are listed here.

Certain medications are generally not recommended to be used with Mesalamine, unless necessary. If you need to take these medications together, your doctor might adjust the dosage or frequency. These include:

  • Aceclofenac, Acemetacin, Amtolmetin Guacil, Balsalazide, and many others listed above.

Additionally, some medications might increase the risk of side effects when taken with Mesalamine, but might still be necessary. In such cases, your doctor will closely monitor your treatment:

  • Tamarind and Warfarin.

Please also note that this medication may interfere with specific lab tests, such as urine normetanephrine levels, potentially leading to false results. It's important to let the lab personnel and all your healthcare providers know that you are using Mesalamine.

Rowasa FAQs
What is the drug ROWASA used for?

ROWASA is used to treat ulcerative colitis, specifically to manage inflammation in the rectum and lower part of the colon. It contains mesalamine, which helps reduce symptoms such as rectal bleeding, diarrhea, and abdominal pain.

Yes, Rowasa is a brand name for a medication that contains mesalamine. Mesalamine is used to treat inflammatory bowel diseases such as ulcerative colitis.

ROWASA (mesalamine) is generally considered effective for treating mild to moderate ulcerative colitis, particularly in the distal colon and rectum. It works by reducing inflammation in the colon lining. Clinical studies have shown that many patients experience symptom relief and mucosal healing with its use. However, individual responses can vary, and it is important for patients to follow their healthcare provider's guidance for optimal results.

Mesalamine has not been universally discontinued. It is still available and commonly used for the treatment of inflammatory bowel diseases such as ulcerative colitis. However, specific formulations or brands of mesalamine may be discontinued by manufacturers for various reasons, such as changes in market demand, production costs, or the introduction of newer formulations. Patients should consult their healthcare provider for alternatives if they are affected by a specific discontinuation.

ROWASA enema is used to treat inflammation in the lower part of the colon and rectum, commonly associated with ulcerative colitis. It contains mesalamine, which helps reduce symptoms such as rectal bleeding, diarrhea, and abdominal pain by decreasing inflammation in the colon lining.