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Sulfasalazine

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generic Azulfidine, Azulfidine En-tabs

Sulfasalazine is used to treat a certain type of bowel disease called ulcerative colitis. This medication does not cure this condition, but it helps decrease symptoms such as fever, stomach pain, diarrhea, and rectal bleeding. After an attack is treated, sulfasalazine is also used to increase the amount of time between attacks. This medication works by reducing irritation and swelling in the large intestines. In addition, delayed-release tablets of sulfasalazine are used to treat rheumatoid arthritis. Sulfasalazine helps to reduce joint pain, swelling, and stiffness. Early treatment of rheumatoid arthritis with sulfasalazine helps to reduce/prevent further joint damage so you can do more of your normal daily activities. This medication is used with other drugs, rest, and physical therapy in patients who have not responded to other medications (salicylates, nonsteroidal anti-inflammatory drugs-NSAIDs).
Our coupons are free to use. Before paying, show the pharmacist your Sulfasalazine savings card to get your free discount. Use our filters below to edit the prescription box to match your needs. The Sulfasalazine prices will update based on your prescription needs. Above our Sulfasalazine coupons, you can change your location to see pharmacy prices and costs in other areas. We're here to help you buy Sulfasalazine at the lowest price with our prescription discount card.

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500MG, Sulfasalazine (30 Tablets)

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CVS

$23.19

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Walgreens

$2.00

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Walmart

$7.37

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Rite Aid

$8.54

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Albertsons

$14.19

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Sulfasalazine savings card

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Sulfasalazine dosage forms

The average cost for 30 tablets of 40mg of Sulfasalazine (generic Azulfidine, Azulfidine En-tabs) is $6.60 with a free coupon. This is 89.91% off the average retail price of $65.44.
DosageQuantityPrice fromPer unit
500MG30 Tablets$2$0.07

Sulfasalazine Side Effects

You might experience mild side effects such as stomach upset, nausea, vomiting, loss of appetite, headache, dizziness, or unusual tiredness. These are generally not serious, but if they persist or worsen, you should inform your healthcare provider. Another common effect is a harmless change in the color of your skin and urine to an orange-yellow, which will resolve once the medication is stopped.

In some cases, you might notice delayed-release tablets of sulfasalazine in your stool, either whole or partially dissolved. If this happens, it's important to notify your healthcare provider promptly to adjust your treatment.

Should you experience more serious side effects, such as changes in hearing, mood alterations, signs of kidney issues (like painful urination or blood in urine), new growths in the neck, or symptoms of low blood sugar (such as blurred vision or fast heartbeat), seek medical advice immediately.

Though rare, very serious side effects can occur. These include severe allergic reactions, blood disorders, liver damage, and nerve or muscle problems. Watch for symptoms such as persistent or severe headaches, skin rashes, mouth sores, itching or swelling (especially of the face, tongue, or throat), severe dizziness, or difficulty breathing. Also, be alert for signs of infection, unusual bruising or bleeding, extreme tiredness, or joint pain. If any of these occur, seek emergency medical attention.

This summary does not cover all possible side effects. If you experience any other unusual effects, contact your healthcare provider.

Interactions

Certain medications and substances can interact with this drug. These include digoxin, folic acid, oral methenamine, and oral PABA. Additionally, sulfasalazine is closely related to mesalamine, so do not take mesalamine orally while using sulfasalazine. This medication might also affect some laboratory tests, like urine normetanephrine levels and liver function tests, potentially leading to incorrect results. Be sure to inform lab staff and all of your healthcare providers that you are using this medication.
Sulfasalazine FAQs
Does sulfasalazine make you gain weight?

Sulfasalazine is not commonly associated with weight gain as a side effect. However, individuals may experience different reactions to medications. If there are concerns about weight changes while taking sulfasalazine, it is advisable to consult with a healthcare provider for personalized advice and evaluation.

Sulfasalazine is used to treat inflammatory bowel diseases such as ulcerative colitis and Crohn's disease. It is also used to manage rheumatoid arthritis. The drug works by reducing inflammation in the body.

The safety of methotrexate versus sulfasalazine depends on the individual patient's condition, medical history, and specific health needs. Both medications have potential side effects and risks. Methotrexate can affect liver function and blood cell counts, and may cause gastrointestinal issues. Sulfasalazine can cause gastrointestinal disturbances and may affect liver function and blood cell counts as well. It is important for a healthcare provider to evaluate the patient's overall health and treatment goals to determine which medication is safer for their specific situation. Regular monitoring and follow-up are essential when using either medication.

Sulfasalazine may interact with several medications. It is important to avoid taking it with:1. Methotrexate: This combination can increase the risk of liver damage.2. Warfarin: Sulfasalazine can enhance the effects of warfarin, increasing the risk of bleeding.3. Digoxin: Sulfasalazine may reduce the absorption and effectiveness of digoxin.4. Folic Acid: Sulfasalazine can interfere with the absorption of folic acid, potentially leading to deficiency.5. Antibiotics: Some antibiotics may reduce the effectiveness of sulfasalazine.Patients should always consult with their healthcare provider before starting or stopping any medications to ensure safety and efficacy.

Sulfasalazine is not being universally discontinued. However, there may be specific reasons for its discontinuation in certain cases, such as individual patient intolerance, adverse effects, or the availability of more effective treatments for specific conditions. It is important for patients to consult with their healthcare provider to understand the specific reasons for any changes in their medication regimen.