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The following safety information outlines crucial warnings regarding the use of this medication. It is important to understand these risks and precautions, and consult your healthcare provider if you have any concerns.

• Hormonal Changes: Overuse of topical steroids like clobetasol can disrupt your body's hormone production, potentially impacting several bodily functions. This can lead to elevated blood sugar levels or increased bruising of the skin. The risk is heightened with prolonged use, large application areas, high doses (more than 2 grams daily), or if the area is covered with a bandage. Younger individuals are also at greater risk. To mitigate these effects, your healthcare provider will recommend the minimal effective dose for the shortest duration. Regular lab tests might be necessary if extended use is required. Avoid using clobetasol beyond 2 weeks (or 4 weeks for the shampoo) unless directed otherwise by your provider.

• Elevated Blood Sugar: Prolonged application of clobetasol over extensive body areas can increase blood sugar levels, potentially leading to diabetes. If you have diabetes, it's crucial to monitor your blood sugar levels consistently while using this medication to ensure its safety.

• Infection Risk: Clobetasol can weaken your immune response, leading to a higher likelihood of skin infections. It is important to address any skin infections with suitable antifungal or antibacterial treatments. Discontinue use and contact your healthcare provider immediately if you experience redness, pain, swelling, or pus at the site of application.

• Skin Reactions: Extended use of clobetasol can cause various skin issues such as thinning, stretch marks, spider veins, burning, itching, irritation, dryness, inflamed hair follicles, color changes, or rash. Some of these effects may be irreversible. To avoid these reactions, adhere to the prescribed dose and duration. Report any new or worsening skin conditions to your provider promptly.

No specific contraindications are available for this medication. Always follow your healthcare provider's instructions and guidance when using clobetasol to ensure safe and effective treatment.

When applying this medication to the skin, you may initially experience some burning, stinging, itching, dryness, or redness. These are common side effects and should subside as your body adjusts. If they persist or worsen, it's important to consult your healthcare provider. Other mild side effects may include dry skin, rash, thinning of the skin, small red bumps, changes in skin color, stretch marks, and, if used on the scalp, hair loss. Although these effects can be concerning, they are generally not serious and often resolve with time.

However, there are more serious side effects that require immediate medical attention. These include skin thinning or discoloration, extreme or unwanted hair growth, and worsening skin infections, which can occur with prolonged use. Rarely, the medication may be absorbed into the bloodstream, causing symptoms such as unusual tiredness, weight loss, headaches, swelling of the ankles or feet, increased thirst or urination, and vision problems. Children and those using the medication over large areas or for extended periods are more at risk.

In extremely rare cases, a serious allergic reaction may occur. Symptoms to watch for include rash, swelling (particularly of the face, tongue, or throat), severe dizziness, and difficulty breathing. If you notice any unusual effects not listed here, it's important to consult your healthcare provider for further guidance.