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Idelalisib is associated with several serious health risks, and it is important to be aware of these while undergoing treatment. Below are potential risks and precautions to consider:

• Liver Health: Idelalisib may lead to severe, potentially fatal liver damage. Regular liver function tests will be conducted by your healthcare provider. Be vigilant and report immediately if you experience persistent nausea or vomiting, loss of appetite, stomach or abdominal pain, jaundice (yellowing of eyes or skin), or dark-colored urine.

• Gastrointestinal Concerns: This medication may cause severe diarrhea and, in rare cases, a gastrointestinal perforation. Contact your doctor promptly if you experience persistent diarrhea, abdominal or stomach pain, cramping, blood or mucus in your stool, fever, nausea, vomiting, or any signs of dizziness or fainting.

• Lung Issues: Idelalisib can induce serious lung problems, including pneumonitis, which can be life-threatening. Notify your healthcare provider immediately if you notice symptoms such as a worsening cough, shortness of breath, difficulty breathing, or wheezing.

• Infection Risk: Your immune response may be compromised, increasing susceptibility to serious infections, which can occasionally be fatal. Your doctor might prescribe antibiotics to prevent infections during and after your treatment. Adhere strictly to all instructions given by your healthcare provider. Seek urgent medical attention if you develop symptoms like a persistent sore throat, fever, chills, cough, or any new or worsening swelling of lymph nodes.

Your safety is paramount, and following these precautions diligently can help manage the risks associated with Idelalisib. Always communicate openly with your healthcare provider about any concerns or symptoms you experience.

When taking this medication, some common side effects may include diarrhea, headache, heartburn, mouth or throat sores, and difficulty sleeping. These are generally mild, but if they persist or worsen, it is important to inform your healthcare provider. Among the more serious side effects are easy bruising or bleeding, swelling in the hands, ankles, or feet, and sudden changes in vision. Immediate medical attention is recommended if any of these occur.

While a rash is a common side effect that is typically not severe, it can sometimes indicate a more serious condition. Seeking medical advice is crucial if a rash develops. Idelalisib can also weaken the immune system, increasing the risk of infections, including a rare but potentially fatal brain infection known as progressive multifocal leukoencephalopathy (PML). Symptoms of PML such as clumsiness, loss of coordination, weakness, sudden changes in thinking, difficulty talking or walking, and seizures require urgent medical care.

Although a severe allergic reaction to this drug is rare, it is essential to seek immediate help if symptoms such as a rash, itching, swelling of the face, tongue, or throat, severe dizziness, or difficulty breathing occur. This overview does not cover all possible side effects, so if other symptoms arise, contacting a healthcare professional is advised.