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This medication has important safety information that you should be aware of before use. Please read the following carefully and discuss any concerns with your healthcare provider.

• Pregnancy Warning: This medication can cause severe, potentially life-threatening harm to an unborn baby. It is crucial to avoid pregnancy while using this medication. Discuss reliable birth control methods with your doctor. If you are pregnant, planning to become pregnant, or suspect you might be pregnant, inform your healthcare provider immediately and discontinue the use of the medication.

• Low Blood Pressure: Use of this medication may result in excessively low blood pressure, leading to symptoms like dizziness, fatigue, or lightheadedness, particularly if you are dehydrated from conditions such as diarrhea, vomiting, or heart failure. Ensure your fluid and salt levels are balanced before starting the medication. Stay hydrated, and rise slowly from sitting or lying positions to prevent dizziness. If you experience a significant drop in blood pressure, contact your healthcare provider. Seek emergency help if you fall and injure yourself.

• Kidney Concerns: While this medication generally protects kidney function, it can occasionally cause kidney injury, particularly in individuals with severe heart failure, renal artery stenosis, or dehydration. Report any issues with urination to your doctor as it may indicate kidney impairment.

• Electrolyte, Blood Sugar, and Cholesterol Changes: This medication can alter electrolyte levels (sodium, potassium, magnesium), blood sugar, and cholesterol levels. This risk increases if you are taking other medications that affect these parameters. Regular monitoring by your healthcare provider is advisable.

• Allergic Reactions: Allergic reactions are possible, especially if you have a history of allergies, asthma, or sulfa allergies. Symptoms like rash, itching, hives, breathing difficulties, or facial swelling should be reported to your doctor immediately.

• Vision Issues: Some individuals may experience vision changes or eye pain shortly after starting this medication. Report any vision alterations to your healthcare provider promptly, as untreated symptoms could lead to permanent vision damage.

• Lupus: This medication may induce or exacerbate lupus symptoms, such as extreme fatigue, joint pain, or a distinct facial rash. Discuss any lupus symptoms with your healthcare provider.

Contraindications:

• This medication should not be used if you are unable to urinate, are taking aliskiren (Tekturna) concurrently if you have diabetes, or if you have allergies to candesartan, hydrochlorothiazide, or other sulfa drugs. Always consult your healthcare provider if any of these conditions apply to you before taking this medication.

When taking this medication, it's common to experience some mild side effects as your body adjusts. These include dizziness, lightheadedness, upper respiratory tract infections, back pain, and flu-like symptoms. To minimize dizziness and lightheadedness, try to rise slowly from sitting or lying down. While these side effects are generally not serious, consult your healthcare provider if they persist or worsen.

Some users may also encounter side effects such as cough, itching, rash, muscle spasms, blurry vision, and stomach cramps. These symptoms should be monitored, and any concerns should be discussed with your healthcare provider.

More serious side effects, although rare, require immediate medical attention. These include symptoms of dangerously low blood pressure like severe dizziness or fainting, signs of kidney problems such as reduced urination or swelling, and abnormal electrolyte levels indicated by nausea, muscle cramps, or a fluttering heartbeat. Vision problems like eye pain or changes in vision should also be addressed promptly.

In some cases, a severe allergic reaction may occur, characterized by a rash, trouble breathing, or swelling of the face, lips, or throat. If you experience any of these symptoms, seek urgent medical care. Always be vigilant for any unusual reactions and consult your healthcare provider for further advice.

When taking Atacand HCT (Candesartan/Hydrochlorothiazide), be aware of potential interactions with other medications. It's important to inform your doctor and pharmacist about all other medicines and supplements you are using, including both prescription and over-the-counter drugs, as well as vitamins and herbal supplements.

Some interactions with Atacand HCT are not recommended. For example, using it with Dofetilide is generally discouraged. In some situations, your doctor might choose to adjust your treatment plan or dosage if you are taking medicines like Benazepril, Lisinopril, Lithium, certain birth control pills containing drospirenone, or products that may elevate potassium levels in your blood, such as sparsentan.

Additionally, some medications could raise your blood pressure or exacerbate heart failure, including NSAIDs like Ibuprofen or Naproxen, and other similar drugs. These might require careful management or dosage changes if used with Atacand HCT.

Moreover, Atacand HCT may interfere with laboratory tests such as those for parathyroid function or protein-bound iodine, potentially leading to inaccurate results. Ensure that all healthcare providers and lab technicians are aware you are taking this medication. Always discuss with your healthcare provider before making any changes to your medication regimen.