Probenecid Coupons & Discount Card - Compare Prices Near You
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500MG, Probenecid (30 Tablets)
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CVS
$42.60
COUPON PRICE
Walgreens
$5.67
COUPON PRICE
Rite Aid
$30.62
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Albertsons
$38.82
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Walmart
$41.94
COUPON PRICEProbenecid savings card
Show this card to your pharmacistCVS
$42.60
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019876
LH529DF342
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More prescriptions for gout
More prescriptions for gout
Probenecid dosage forms
| Dosage | Quantity | Price from | Per unit |
|---|---|---|---|
| 500MG | 30 Tablets | $5.67 | $0.19 |
Probenecid Warnings
This medication comes with important safety information that you should be aware of. Please read the following warnings and contraindications carefully and discuss any concerns with your healthcare provider.
Kidney Stones: While taking this medication for gout, there is a possibility of developing kidney stones. It is advised to drink plenty of water daily during treatment. Contact your healthcare provider if you experience severe back or stomach pain, blood in your urine, or fever and chills, as these could be signs of kidney stones.
Blood Problems in Certain Individuals: Individuals with a genetic condition known as Glucose-6-phosphate dehydrogenase (G6PD) deficiency may have an increased risk of encountering rare but serious blood issues, such as low white blood cell counts or anemia (low red blood cell counts). Symptoms of low white blood cell counts include frequent illnesses, while anemia can present as fatigue, weakness, dizziness, or pale skin. If you have G6PD deficiency or experience these symptoms, consult your healthcare provider to explore alternative gout medications.
Contraindications: There are specific conditions under which this medication should not be used due to the potential for severe health risks. Consult your healthcare provider if any of the following apply to you:
- Children under 2 years of age
- Existing blood problems
- History of uric acid kidney stones
- Concurrent use of aspirin
Always follow your healthcare provider’s guidance and report any adverse effects or concerns during your treatment.
Probenecid Side Effects
Common side effects:
- nausea
- headache
- dizziness
- vomiting
- loss of appetite
- sore gums
- frequent urination
Less common but important to monitor:
- sudden gout attacks
- formation of kidney stones
Serious side effects:
- lower back pain
- difficult or painful urination
- changes in urine color or amount
- easy bruising or bleeding
- signs of infection like fever and sore throat
- severe abdominal pain
- pale stools
- unusual tiredness
- dark urine
- yellowing of the eyes or skin
- very serious allergic reaction
Probenecid Interactions
Interactions with high risk of serious adverse effects and should be avoided:
Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:
- Avibactam
- Baricitinib
- Cephalexin
- Citalopram
- Deferiprone
- Doripenem
- Indomethacin
- Lumateperone
- Methotrexate
- Naproxen
- Pegloticase
- Pexidartinib
- Sacituzumab Govitecan-hziy
- Zalcitabine
Interactions with low risk that usually do not require a change in therapy:
- Amoxicillin
- Aspirin
- Bismuth Subsalicylate
- CefditorenPivoxil
- Cefotaxime
- CefpodoximeProxetil
- Cefprozil
- Choline Magnesium Trisalicylate
- Ciprofloxacin
- Enprofylline
- Ertapenem
- Gatifloxacin
- Lorazepam
- Magnesium Salicylate
- Meropenem
- Norfloxacin
- Phenprocoumon
- Piretanide
- Pralatrexate
- Sodium Salicylate
- Sodium Thiosalicylate
- Zidovudine
- Zomepirac
What is the function of probenecid?
Probenecid is primarily used to treat gout and hyperuricemia by increasing the excretion of uric acid in the urine. It works by inhibiting the reabsorption of uric acid in the kidneys, thereby lowering uric acid levels in the blood. Additionally, probenecid can be used to prolong the effects of certain antibiotics by reducing their excretion from the body.
Why is probenecid banned?
Probenecid is not banned for medical use; it is a legitimate medication used to treat gout and to increase the effectiveness of certain antibiotics. However, it is banned in sports by organizations like the World Anti-Doping Agency (WADA) because it can be used as a masking agent to hide the presence of performance-enhancing drugs in an athlete's system.
What does probenecid do to the kidneys?
Probenecid affects the kidneys by inhibiting the renal tubular secretion of certain substances, including uric acid. This action helps to increase the excretion of uric acid in the urine, thereby lowering uric acid levels in the blood. It is often used in the management of gout to prevent gout attacks by reducing hyperuricemia. Additionally, probenecid can also affect the excretion of other drugs, potentially increasing their levels in the body.
What is the best substitute for allopurinol?
A common substitute for allopurinol is febuxostat. Both medications are used to lower uric acid levels in the blood and are typically prescribed for the management of gout. However, the choice between these medications should be made by a healthcare provider, considering the patient's specific medical condition, history, and any potential side effects.
What is the mode of action of probenecid?
Probenecid works by inhibiting the renal tubular reabsorption of uric acid, which increases the excretion of uric acid in the urine. This helps to lower the levels of uric acid in the blood, making it useful in the treatment of gout and hyperuricemia. Additionally, probenecid can inhibit the renal excretion of certain drugs, thereby increasing their plasma concentrations and prolonging their effects.