Parkinson's DiseaseCarbidopa-levodopa ER coupons
Carbidopa-levodopa ER

Carbidopa-levodopa ER Coupons & Discount Card – Guaranteed Prices from $5.32

generic Rytary, Crexont

Sinemet, a combination of carbidopa and levodopa, is commonly prescribed to manage Parkinson's disease and similar conditions that cause symptoms like shakiness, stiffness, and difficulty in movement. The main issue in Parkinson's is the lack of dopamine, a crucial substance for controlling movement. Levodopa works by converting into dopamine in the brain, thus helping improve movement control. Carbidopa aids by preventing the breakdown of levodopa before it reaches the brain, enhancing its effectiveness and minimizing side effects such as nausea and vomiting. It's important that Sinemet is taken several times a day for optimal symptom relief. Always consult with your healthcare provider before starting or changing your treatment regimen.
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25-100MG, Carbidopa-levodopa ER (30 Tablet Extended Releases)

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CVS

$19.71

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Walgreens

$5.32

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Walmart

$7.06

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$7.99

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$14.89

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Carbidopa-levodopa ER savings card

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$5.32

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Carbidopa-levodopa ER dosage forms

The average cost for 30 Tablet Extended Releases of Carbidopa-levodopa ER (generic Rytary, Crexont) at 50-200MG is $9.24 with a free coupon. This is 60% off the average retail price of $23.1
DosageQuantityPrice fromPer unit
50-200MG30 Tablet Extended Releases$9.24$0.31
25-100MG30 Tablet Extended Releases$5.32$0.18

Carbidopa-levodopa ER Warnings

The following safety information outlines the potential risks and precautions associated with the use of Sinemet (carbidopa/levodopa). Please review this information carefully and consult your healthcare provider if you have any questions or concerns.

  • Drowsiness and Sudden Sleep Episodes: Sinemet may cause unexpected sleepiness or sudden sleep episodes during daily activities. Until you understand how this medication affects you, refrain from operating vehicles or engaging in tasks that require full attention, especially if you have a history of drowsiness or sleep problems. Avoid combining Sinemet with other sedative medications, as this can increase drowsiness. Notify your healthcare provider if you experience excessive daytime sleepiness or fall asleep during activities requiring concentration.

  • High Fevers and Confusion: Abruptly stopping or reducing the dose of Sinemet can lead to symptoms similar to neuroleptic malignant syndrome (NMS), a potentially life-threatening condition. Symptoms may include high fever, confusion, irregular heartbeat, sweating, muscle rigidity, and blood pressure changes. Do not discontinue or adjust your dose without consulting your healthcare provider to ensure a safe cessation plan.

  • Hallucinations and Behavioral Changes: Sinemet may induce hallucinations or alter behavior and thought processes, potentially leading to paranoia, delusions, confusion, aggression, restlessness, sleep disturbances, vivid dreaming, and decreased situational awareness. These effects generally appear soon after starting treatment and may resolve upon discontinuation or dosage adjustment. Sinemet should not be used in individuals with certain mental health disorders. Some mental health medications, like haloperidol or perphenazine, can exacerbate Parkinson's symptoms and interfere with Sinemet’s efficacy.

  • Impulse Control Issues: The medication may lead to impulsive behaviors, such as increased sexual urges, gambling, excessive spending, or binge eating. If these behaviors adversely affect your life, inform your healthcare provider. Since you may not recognize these urges, your provider may inquire about any recent occurrences during follow-up visits.

  • Increased Risk of Skin Cancer: Parkinson's disease patients have an elevated risk of developing skin cancer. Regularly monitor your skin for new or unusual growths or changes in moles, and inform your healthcare provider of any concerns. Periodic skin evaluations may be recommended.

Contraindications: Do not use Sinemet if you are taking nonselective monoamine oxidase inhibitors (MAOIs) or if you have narrow-angle glaucoma. Discuss with your healthcare provider if these conditions apply to you before starting the medication.

Carbidopa-levodopa ER Side Effects

Common side effects:

  • Dizziness
  • Lightheadedness
  • Nausea
  • Vomiting
  • Loss of appetite
  • Headaches
  • Trouble sleeping

Less common but important to monitor:

  • Unusual dreams
  • Increased sleepiness
  • Involuntary movements (dyskinesia or dystonia)
  • Mood changes (depression and confusion)

Serious side effects:

  • Neuroleptic malignant syndrome (NMS)
  • Hallucinations
  • Vision changes
  • Severe abdominal pain
  • Black or tarry stools
  • Coffee-ground-like vomit
  • Signs of infection (persistent sore throat or easy bruising)
  • Very serious allergic reaction (rash, severe dizziness, breathing difficulties)

Carbidopa-levodopa ER Interactions

Interactions with high risk of serious adverse effects and should be avoided:

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

Carbidopa-levodopa ER FAQs
Does carbidopa levodopa come in extended-release?

Yes, carbidopa-levodopa is available in an extended-release formulation. This formulation is designed to release the medication slowly over time to help manage symptoms of Parkinson's disease more consistently.

Carbidopa levodopa ER is an extended-release medication used to treat symptoms of Parkinson's disease and Parkinson-like symptoms. It combines carbidopa and levodopa, where carbidopa helps prevent the breakdown of levodopa before it reaches the brain, allowing more levodopa to be converted to dopamine in the brain. This helps improve symptoms such as tremors, stiffness, and slowness of movement. The extended-release formulation allows for a more consistent release of the medication over time.

The sustained release tablets for carbidopa and levodopa are commonly known as Sinemet CR. These tablets are designed to release the medication slowly over time to help manage symptoms of Parkinson's disease more consistently.

Signs of too much carbidopa-levodopa can include nausea, vomiting, dizziness, confusion, hallucinations, involuntary movements (dyskinesia), and irregular heart rhythms. If someone experiences these symptoms, it is important to seek medical attention promptly.

Carbidopa-levodopa is primarily used to treat symptoms of Parkinson's disease and Parkinson-like symptoms. The advantages include:1. Symptom Relief: It helps reduce symptoms such as tremors, stiffness, and slowness of movement, improving overall motor function.2. Increased Dopamine Levels: Levodopa is converted to dopamine in the brain, replenishing the low levels of dopamine that are characteristic of Parkinson's disease.3. Carbidopa's Role: Carbidopa prevents the premature conversion of levodopa to dopamine outside the brain, allowing more levodopa to reach the brain and reducing side effects like nausea.4. Improved Quality of Life: By alleviating symptoms, it can enhance the quality of life for individuals with Parkinson's disease, allowing them to perform daily activities more easily.5. Established Treatment: It is a well-researched and widely used treatment with a long history of effectiveness in managing Parkinson's symptoms.