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Colchicine

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generic Colcrys, Mitigare, Gloperba

This medication is prescribed to prevent or treat gout attacks, which often occur suddenly and typically affect one or a few joints, such as the big toe, knee, or ankle. Gout results from excessive uric acid in the blood, leading to the formation of hard crystals in the joints. Colchicine helps by reducing inflammation and minimizing the accumulation of these painful uric acid crystals. Additionally, this medication is used to prevent pain attacks in the abdomen, chest, or joints associated with familial Mediterranean fever, an inherited condition. It is believed to reduce the production of a specific protein, amyloid A, which builds up in individuals with this disease. It is important to note that Colchicine is not a general pain reliever and should not be used for other types of pain.
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0.6MG, Colchicine (30 Tablets)

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CVS

$19.71

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Rite Aid

$9.16

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Walmart

$11.18

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Albertsons

$20.51

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Walgreens

$50.54

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Colchicine dosage forms

The average cost for 30 Tablets of Colchicine (generic Colcrys, Mitigare, Gloperba) at 0.6MG is $8.66 with a free coupon. This is 6.49% off the average retail price of $133.5
DosageQuantityPrice fromPer unit
0.6MG30 Tablets$8.66$0.29

Colchicine Side Effects

When taking this medication, you might experience diarrhea, nausea, cramping, abdominal pain, or vomiting. These are common side effects and typically mild. However, if they persist or become bothersome, it's important to consult with a healthcare professional.

While the medication is generally safe, there are some serious side effects to be aware of. Discontinue use and seek immediate medical attention if you encounter unusual bleeding or bruising, severe diarrhea or vomiting, muscle weakness or pain, numbness or tingling in the extremities, pale or gray lips, tongue, or palms, persistent sore throat or fever, unusual weakness or fatigue, rapid heartbeat, shortness of breath, or changes in urine output, as these may indicate kidney problems.

Allergic reactions to this drug are rare but can be severe. If you notice symptoms such as rash, itching or swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing, obtain emergency medical help immediately.

This summary does not cover all possible side effects. If you experience any other unusual symptoms, please consult a healthcare provider.

Interactions

Certain medications can influence how colchicine is processed in your body, possibly changing its effectiveness or raising the chance of severe side effects. Examples include Atazanavir, some azole antifungals like Itraconazole and Ketoconazole, diltiazem, macrolide antibiotics such as Clarithromycin and Erythromycin, Ritonavir, telithromycin, and Verapamil. Colchicine can rarely cause a serious muscle condition called rhabdomyolysis, which can lead to severe kidney issues. The risk of this condition may increase if you take other medications that can also cause rhabdomyolysis, such as Digoxin, Gemfibrozil, Pravastatin, and Simvastatin. Additionally, colchicine may affect the results of certain laboratory tests, so ensure your healthcare providers are aware you're using this medication. Avoid taking any other product that contains colchicine at the same time.
Colchicine FAQs
What are the benefits of taking colchicine?

Colchicine is primarily used to treat and prevent gout attacks by reducing inflammation and pain. It is also used in the management of familial Mediterranean fever (FMF) to prevent flare-ups. Additionally, colchicine may be prescribed for pericarditis to reduce inflammation of the pericardium. It is important for patients to follow their healthcare provider's instructions when using colchicine to ensure its effectiveness and minimize potential side effects.

A bad reaction to colchicine can include symptoms such as severe diarrhea, nausea, vomiting, abdominal pain, and muscle weakness. In some cases, it can also cause bone marrow suppression, leading to low blood cell counts, which may result in increased risk of infections, fatigue, or unusual bleeding. If any of these symptoms occur, it is important to seek medical attention promptly.

Colchicine does not clear uric acid from the body. Instead, it is used to reduce inflammation and relieve pain during acute gout attacks. It works by decreasing the build-up of uric acid crystals that cause joint pain. For lowering uric acid levels, medications such as allopurinol or febuxostat are typically prescribed.

Colchicine is a medication primarily used to treat and prevent gout attacks. It works by reducing inflammation and decreasing the build-up of uric acid crystals in the joints, which helps alleviate pain and swelling. Additionally, colchicine is sometimes used to treat familial Mediterranean fever and other inflammatory conditions as prescribed by a healthcare provider.

Individuals who should avoid colchicine include those with severe renal or hepatic impairment, as the drug can accumulate to toxic levels in these conditions. Additionally, people with known hypersensitivity to colchicine should not take it. Caution is also advised for those taking medications that strongly inhibit CYP3A4 or P-glycoprotein, as these can increase colchicine levels and risk of toxicity. Pregnant or breastfeeding women should consult their healthcare provider before using colchicine.