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Colchicine

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generic Colcrys, Mitigare, Gloperba

Colchicine is a medication primarily used to prevent and treat gout attacks, which often occur suddenly and affect joints such as the big toe, knee, or ankle. Gout is caused by elevated uric acid levels in the blood, leading to painful crystal formations in the joints. Colchicine reduces swelling and helps prevent the accumulation of these uric acid crystals, alleviating pain in the affected areas. Additionally, colchicine is the preferred treatment for familial Mediterranean fever (FMF), a hereditary condition that causes pain in the abdomen, chest, or joints. It works by reducing the production of a specific protein known as amyloid A, which accumulates in FMF patients. It is important to note that colchicine is not a general pain reliever and should not be used for other types of pain. This medication is available in tablets, capsules, and oral solutions. Always consult healthcare professionals before starting any medication.
Our coupons are free to use. Before paying, show the pharmacist your Colchicine savings card to get your free discount. Use our filters below to edit the prescription box to match your needs. The Colchicine prices will update based on your prescription needs. Above our Colchicine coupons, you can change your location to see pharmacy prices and costs in other areas. We're here to help you buy Colchicine at the lowest price with our prescription discount card.

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0.6MG, Colchicine (30 Tablets)

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CVS

$19.71

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Rite Aid

$9.37

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Walmart

$11.18

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Albertsons

$24.53

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Walgreens

$50.54

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Colchicine savings card

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CVS

$19.71

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Colchicine dosage forms

The average cost for 30 Tablets of Colchicine (generic Colcrys, Mitigare, Gloperba) at 0.6MG is $8.66 with a free coupon. This is 6.49% off the average retail price of $133.5
DosageQuantityPrice fromPer unit
0.6MG30 Tablets$8.66$0.29

Colchicine Warnings

This document outlines essential safety information and warnings related to the use of colchicine. It is crucial to understand these potential risks and precautions to ensure safe use. Consult your healthcare provider if you have any questions or concerns.

  • Risk of Overdose: Colchicine overdoses can be fatal, whether accidental or intentional, for both adults and children. Always follow your healthcare provider's dosing instructions and keep the medication out of children’s reach. Signs of an overdose include stomach pain, nausea, vomiting, and diarrhea, which can lead to dehydration. In case of an overdose, contact the Poison Control Center at 1-800-222-1222 or seek immediate medical assistance.

  • Blood Cell Issues: Colchicine can affect your body's ability to produce new blood cells, even at prescribed doses. This condition can become serious if not addressed promptly. Regular lab tests are important. Notify your healthcare provider if you experience unusual bleeding, bruising, persistent fever, or fatigue.

  • Drug and Food Interactions: Colchicine can interact with many other drugs, potentially increasing its levels to dangerous amounts. Notable interacting drugs include calcium channel blockers, digoxin, statins, certain antifungals, HIV protease inhibitors, and cyclosporine. Ensure your healthcare provider is aware of all medications you are taking, even if colchicine is used occasionally. Dosage adjustments may be necessary if taking interacting substances.

  • Nerve and Muscle Toxicity: Prolonged use of colchicine can lead to nerve or muscle damage, with potential to cause rhabdomyolysis, a condition where damaged muscle tissue releases harmful proteins into the bloodstream. This risk is heightened by concurrent use of statins, fibrates, or cyclosporine, as well as in individuals with poor kidney function or older adults. Seek medical attention if you experience muscle pain, dark urine, or difficulty moving limbs, as stopping colchicine may be required. Symptoms usually resolve within a week after discontinuation, though in some cases, it may take longer.

  • Contraindications: Avoid using colchicine if you have kidney or liver disease in combination with other interacting medications. Consult your healthcare provider if this applies to you before starting the medication.

Always discuss any concerns or questions with your healthcare provider to ensure safe and effective use of colchicine.

Colchicine Side Effects

Common side effects:

  • Diarrhea
  • Nausea

Less common but important to monitor:

  • Tiredness
  • Headache
  • Throat pain

Serious side effects:

  • Allergic reaction symptoms
  • Rash
  • Itching
  • Hives
  • Swelling of the face, lips, tongue, or throat
  • Symptoms of an infection
  • Fever
  • Chills
  • Persistent sore throat
  • Difficulty in urination
  • Unusual weakness
  • Muscle pain
  • Changes in urine color
  • Unusual bleeding or bruising
  • Pain, tingling, or numbness in extremities

Colchicine Interactions

Interactions with high risk of serious adverse effects and should be avoided:

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

Colchicine FAQs
What does colchicine do exactly?

Colchicine is a medication primarily used to treat and prevent gout attacks. It works by reducing inflammation and decreasing the build-up of uric acid crystals in the joints, which helps alleviate pain and swelling. Additionally, colchicine is sometimes used to treat familial Mediterranean fever and other inflammatory conditions as prescribed by a healthcare provider.

Colchicine does not clear uric acid from the body. Instead, it is used to reduce inflammation and relieve pain during acute gout attacks. It works by decreasing the build-up of uric acid crystals that cause joint pain. For lowering uric acid levels, medications such as allopurinol or febuxostat are typically prescribed.

A bad reaction to colchicine can include symptoms such as severe diarrhea, nausea, vomiting, abdominal pain, and muscle weakness. In some cases, it can also cause bone marrow suppression, leading to low blood cell counts, which may result in increased risk of infections, fatigue, or unusual bleeding. If any of these symptoms occur, it is important to seek medical attention promptly.

Colchicine is primarily used to treat and prevent gout attacks by reducing inflammation and pain. It is also used in the management of familial Mediterranean fever (FMF) to prevent flare-ups. Additionally, colchicine may be prescribed for pericarditis to reduce inflammation of the pericardium. It is important for patients to follow their healthcare provider's instructions when using colchicine to ensure its effectiveness and minimize potential side effects.

Individuals who should avoid colchicine include those with severe renal or hepatic impairment, as the drug can accumulate to toxic levels in these conditions. Additionally, people with known hypersensitivity to colchicine should not take it. Caution is also advised for those taking medications that strongly inhibit CYP3A4 or P-glycoprotein, as these can increase colchicine levels and risk of toxicity. Pregnant or breastfeeding women should consult their healthcare provider before using colchicine.