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The following safety information is crucial for users of Colestipol (Colestid). It is important to understand the potential risks and precautions associated with this medication. Consult your healthcare provider if you have any questions or concerns.

• Choking Hazard: Do not consume Colestipol granules in their dry form to avoid the risk of choking. Always mix the granules with at least 3 ounces of liquid. Swallow tablets one at a time. If you have difficulty swallowing or experience throat discomfort after taking the medication, discuss with your healthcare provider whether this medication is suitable for you.

• Vitamin Absorption Issues: Colestipol may reduce the absorption of vitamins A, D, E, K, and folic acid. Consider taking vitamin supplements if advised by your healthcare provider. Ensure these supplements are taken at least 1 hour before or 4 hours after taking Colestipol to avoid interference.

• Increased Bleeding Risk: Long-term use of Colestipol or concurrent use with blood thinners can increase your bleeding risk due to reduced vitamin K levels. Report any unexplained bruising, blood in stool, or prolonged bleeding to your healthcare provider immediately.

• Drug Interactions: To prevent interaction, take other oral medications at least 1 hour before or 4 hours after Colestipol. This is important for medications such as birth control and thyroid treatments, as Colestipol can affect their absorption and effectiveness.

• Phenylketonuria (PKU) Caution: The granules for oral suspension may contain phenylalanine, which is harmful to individuals with PKU. Confirm with your pharmacist if the formulation is appropriate for your condition.

Remain vigilant about these potential issues and adhere to the guidelines provided for safe use of Colestipol.

When taking this medication, some individuals may experience common side effects such as constipation, gas, stomach pain, bloating, cramps, heartburn, nausea, and vomiting. These effects are usually mild and should subside over time. If they persist or worsen, it is advisable to consult your healthcare provider. To help manage constipation, consider incorporating dietary fiber, staying hydrated, and maintaining regular physical activity. A suitable laxative, as recommended by a pharmacist, may also be beneficial.

In rare cases, more serious side effects can occur, which require immediate medical attention. These include severe stomach or abdominal pain, unusual bleeding or bruising, rapid breathing, and confusion. A blockage in the digestive tract may manifest as severe constipation, intense stomach pain, or blood in your stool. Additionally, although very rare, serious allergic reactions may occur. Symptoms like rash, itching or swelling (particularly of the face, tongue, or throat), severe dizziness, and trouble breathing necessitate urgent medical care.

While not exhaustive, this list covers the potential side effects of the medication. If you notice any other effects, reaching out to your healthcare provider or pharmacist is recommended for further advice and assistance.

Colestipol (Colestid) can interact with several medications, so it is important to inform your healthcare provider about all medications and supplements you are taking, including over-the-counter products, vitamins, and herbal supplements. Some medications that may interact with Colestipol include:

1. Medications that may require careful monitoring or dose adjustments:

   • Bezafibrate
   • Deferasirox
   • Digoxin
   • Mycophenolate Mofetil
   • Mycophenolic Acid

2. Medications that may increase the risk of side effects but could be necessary for treatment:

   • Aceclofenac
   • Diclofenac
   • Diltiazem
   • Ezetimibe
   • Fenofibrate
   • Furosemide
   • Hydrocortisone
   • Tetracycline

Additionally, Colestipol may interact with blood thinners such as Warfarin and Raloxifene. Your doctor may adjust the dosage or frequency of these medications if they are prescribed alongside Colestipol. Always consult your healthcare provider before making any changes to your medication regimen.