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Cholestyramine, also known as Prevalite, is a medication used to help lower high cholesterol levels when combined with a suitable diet. By reducing cholesterol, it decreases the risk of heart attacks and strokes. Additionally, cholestyramine can be used to alleviate itching caused by a bile duct blockage, which is a liver or bile duct disorder. This medication belongs to a class known as bile acid sequestrants or bile acid-binding resins. It functions by attaching to bile acids in the intestines, forming a complex that is then eliminated from the body. As the bile acid levels decrease, the liver utilizes more cholesterol to produce additional bile acids, thereby reducing the overall cholesterol levels in the body. In managing cholesterol, adopting lifestyle changes such as maintaining a low-cholesterol, low-fat diet, exercising, losing excess weight, and quitting smoking can enhance the effectiveness of cholestyramine. It is important to consult your healthcare provider for personalized advice. While using this medication, some individuals may experience side effects like constipation, gas, or stomach discomfort. Always consult a healthcare professional before starting any new treatment.