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Cholestyramine is a medication primarily used to lower cholesterol levels in the blood, which in turn reduces the risk of heart attacks and strokes. This drug is most effective when combined with a low-cholesterol, low-fat diet, and lifestyle changes like regular exercise, weight loss, and quitting smoking. Additionally, Cholestyramine is used to alleviate itching in patients with liver or bile duct disease, specifically when there is a partial bile duct obstruction. Cholestyramine belongs to a class of drugs known as bile acid-binding resins or sequestrants. It operates by binding to bile acids in the intestines, forming a complex that is eliminated from the body. This process prompts the liver to convert more cholesterol into bile acids to replace those that are lost, thereby lowering cholesterol levels. For those experiencing itching due to excess bile acid, the reduction in bile acid levels can provide relief. Patients should be aware that Cholestyramine may cause gastrointestinal side effects such as constipation, gas, and stomach discomfort. It is important to consult with healthcare professionals before starting this medication to ensure it is safe and appropriate for your condition.