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Dantrolene (Dantrium) Safety Information and Warnings

Dantrolene, used for muscle relaxation, carries certain risks and precautions that must be observed to ensure safe use. It is important to be aware of these potential risks and communicate with your healthcare provider if you have any concerns.

• Liver Health Risks: There is a rare but serious risk of liver damage, which can be life-threatening. This risk increases if you consume high doses (over 400-800 mg daily), are female, over 35 years old, or are taking other medications that may impact liver function. Liver issues might not present immediately and can develop after 3 to 12 months of treatment. Regular liver function tests are crucial to monitor your liver health.

• Symptoms of Liver Problems: Be vigilant for signs such as persistent nausea or vomiting, abdominal pain, dark urine, yellowing of the eyes or skin, or unusual fatigue. Immediate medical attention is required if these symptoms appear.

• Dosage Instructions: To minimize side effects, adhere strictly to the prescribed dosage. Do not increase the dose or duration of use beyond what your doctor recommends. If there is no improvement in your condition after 45 days of treatment, consult your healthcare provider to discuss discontinuing the drug.

• Contraindications: Avoid using dantrolene if you have pre-existing liver problems, as it may exacerbate your condition.

By following these guidelines and maintaining open communication with your healthcare provider, you can effectively manage the risks associated with dantrolene.

When starting this medication, you might experience some common side effects such as drowsiness, dizziness, weakness, tiredness, nausea, diarrhea, and fatigue. These effects are usually mild and tend to diminish as your body adjusts to the treatment. Additionally, you may notice headaches, constipation, trouble speaking, drooling, or even an upset stomach. If any of these symptoms persist or worsen, it is advisable to consult your healthcare provider for guidance.

Less commonly, some individuals report a loss of appetite, vomiting, feeling lightheaded, trouble sleeping, or changes in vision. While these symptoms are not as frequent, it is still important to monitor them and discuss any concerns with your healthcare provider.

There are rare but serious side effects that require immediate medical attention. These include severe constipation, mental or mood changes, problems with urination, seizures, a fast heartbeat, and signs of infection such as a persistent sore throat, fever, or chills. Additionally, any experience of vision changes, black or tarry stools, vomit resembling coffee grounds, chest pain, swelling of the ankles or feet, or difficulty swallowing should be addressed promptly.

A very serious allergic reaction is rare but warrants urgent medical help. Symptoms of such a reaction include rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, or trouble breathing. In some cases, liver issues may occur, indicated by symptoms like stomach bloating, yellowing of the skin or eyes, and dark urine. Always seek immediate medical attention if you suspect a severe side effect is occurring.