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Dantrolene has been linked to rare but potentially fatal liver issues. This risk increases for those taking high doses (over 400-800 mg daily), women, individuals over 35, and those on other medications. Liver complications typically emerge within 3-12 months of treatment. To minimize this risk, regular liver function tests are necessary. Contact your doctor immediately if you notice persistent nausea or vomiting, stomach or abdominal pain, dark urine, yellowing of the eyes or skin, or unexplained fatigue.

To further lower the risk of side effects, stick to the prescribed dose and treatment duration, using the smallest effective dose. If no improvement is observed after 45 days, inform your doctor, as discontinuation of dantrolene may be necessary.

When starting this medication, you might experience mild side effects such as drowsiness, dizziness, weakness, tiredness, nausea, and diarrhea. These usually decrease as your body adjusts. Headache, constipation, difficulty speaking, and drooling may also occur but tend to improve over time. If these persist or worsen, it's important to consult your healthcare provider.

While most people using this medication do not experience severe side effects, it's crucial to be aware of them. Seek medical attention immediately if you experience severe or persistent constipation, vision changes, black or tarry stools, vomiting resembling coffee grounds, mood or mental changes, difficulty swallowing, urination problems, seizures, a rapid heartbeat, unusual bruising or bleeding, infection symptoms like persistent sore throat, fever, or chills, chest pain, or swelling of the ankles or feet.

A serious allergic reaction to this medication is rare but requires urgent medical attention if it occurs. Symptoms to watch for include rash, itching or swelling especially of the face, tongue, or throat, severe dizziness, and difficulty breathing. Always stay vigilant and contact a healthcare professional if you notice any side effects, even if they are not listed here.