
Estradiol Valerate Coupons & Discount Card – Guaranteed Prices from $36.83
generic Delestrogen
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5ML of 10MG/ML, Estradiol Valerate (1 Vial)
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CVS
$101.18
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Walgreens
$36.83
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Rite Aid
$87.02
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Albertsons
$94.20
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Walmart
$114.47
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Walgreens
$36.83
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019876
LH143DBC25
CHIPPO
LHX
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More prescriptions for estrogen replacement
More prescriptions for estrogen replacement
Estradiol Valerate dosage forms
Dosage | Quantity | Price from | Per unit |
---|---|---|---|
5ML of 10MG/ML | 1 Vial | $36.83 | $36.83 |
5ML of 20MG/ML | 1 Vial | $50.47 | $50.47 |
5ML of 40MG/ML | 1 Vial | $85.04 | $85.04 |
Estradiol Valerate Warnings
The use of estrogen-containing medications, whether alone or combined with progestin, carries certain risks and necessitates careful consideration. Below are essential safety warnings and precautions for individuals considering or currently using such treatments. It is important to discuss these aspects with your healthcare provider to ensure safe and effective use.
Cancer Risks: Estrogen therapies can increase the risk of uterine (endometrial) and breast cancer. For those with a healthy uterus, combining estrogen with progestin can help mitigate the risk of endometrial cancer. Regular monitoring and reporting of unusual vaginal bleeding or changes in breast appearance are crucial. Avoid estrogen therapies if you currently have or have had breast cancer.
Cardiovascular Concerns: There is an elevated risk of developing blood clots, heart attacks, and strokes with estrogen use. This risk is heightened in individuals who smoke or have a history of cardiovascular issues. Immediate medical attention is required if you experience symptoms such as chest pain, severe headaches, or sudden vision changes.
Dementia: Estrogen therapy may increase the risk of dementia, particularly in women over 65. Estrogen and progestin should not be used as a preventive measure against dementia.
Gallbladder and Liver Issues: Estrogen use can lead to gallbladder problems and aggravate liver conditions. If you experience symptoms like persistent stomach pain or jaundice, contact your healthcare provider immediately. Those with a history of liver problems should avoid this medication.
Metabolic Effects: Estrogens can elevate triglyceride levels, potentially leading to heart issues or pancreatitis. Regular blood tests may be necessary to monitor these levels.
Thyroid and Calcium Levels: Estrogen can influence thyroid hormone and calcium levels in the blood. If you have thyroid issues or breast cancer that has spread to bones, consult your provider about potential risks.
Fluid Retention and Other Conditions: Estrogen might cause fluid retention, potentially exacerbating heart or kidney problems. It may also worsen conditions such as high blood pressure, asthma, diabetes, migraines, and seizures. Discuss your full medical history with your healthcare provider before starting treatment.
Contraindications: Do not use estrogen therapy if you have unexplained vaginal bleeding, a history of estrogen-dependent cancers, blood clots, or if you are currently pregnant.
In case of an overdose, seek emergency medical attention immediately. Regular consultations with your healthcare provider are advised to evaluate the need for continued use of hormone therapy. Always use the lowest effective dose for the shortest duration necessary.
Estradiol Valerate Side Effects
Common side effects:
- nausea
- vomiting
- headache
- breast tenderness or growth
- bloating
- weight changes
- stomach cramps
- vaginal spotting or breakthrough bleeding
- dizziness
- high blood pressure
- melasma (dark patches on the skin)
- menstrual cramps
- mood changes
- trouble tolerating contact lenses
Less common but important to monitor:
- persistent unusual vaginal bleeding
- increased thirst or urination
- mental/mood changes
- breast lumps
Serious side effects:
- serious allergic reactions (rash, itching, swelling, severe dizziness, breathing difficulties)
- heart attack
- stroke
- deep vein thrombosis
- pulmonary embolism
- chest pain
- sudden severe headaches
- confusion
- trouble speaking
- pain/swelling in the legs
- liver or gallbladder issues (yellowing of the skin or eyes, dark urine, severe abdominal pain)
Estradiol Valerate Interactions
Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:
- Aromatase inhibitors (such as anastrozole, exemestane, letrozole)
- Fezolinetant
- Fulvestrant
- Ospemifene
- Raloxifene
- Tamoxifen
- Toremifene
- Tranexamic acid
What is estradiol valerate used for?
Estradiol valerate is used primarily for hormone replacement therapy in postmenopausal women to manage symptoms such as hot flashes and vaginal dryness. It is also used in the treatment of hypoestrogenism due to hypogonadism, castration, or primary ovarian failure. Additionally, it can be part of hormone therapy for transgender women and is sometimes used in the management of certain types of prostate cancer.
Why would a man take estradiol valerate?
Estradiol valerate may be prescribed to a man for several reasons, including hormone therapy for transgender women as part of gender-affirming treatment, to manage symptoms of hormone-sensitive cancers such as prostate cancer, or to address hormonal imbalances. It is important for individuals to follow their healthcare provider's guidance when using this medication.
Why would a doctor prescribe estrogen to a man?
A doctor might prescribe estrogen to a man for several reasons, including hormone therapy for transgender women, treatment of prostate cancer, or management of certain conditions like gynecomastia. Estrogen can help in feminizing hormone therapy by promoting the development of female secondary sexual characteristics. In prostate cancer, estrogen can help reduce testosterone levels, which may slow the growth of cancer cells.
What's the difference between estradiol and estradiol valerate?
Estradiol and estradiol valerate are both forms of estrogen used in hormone therapy, but they differ in their chemical structure and administration. Estradiol is the natural form of estrogen, while estradiol valerate is a prodrug, meaning it is converted into estradiol in the body. Estradiol valerate is often used in injectable form, allowing for a longer duration of action compared to oral estradiol. This difference in formulation can affect the choice of treatment based on the patient's needs and the desired method of administration.
What is the most common side effect of estradiol?
The most common side effect of estradiol is nausea. Other frequent side effects may include headache, breast tenderness, and irregular vaginal bleeding or spotting. It is important for individuals to discuss any side effects they experience with their healthcare provider.