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The EXPAREL controversy primarily revolves around debates concerning its efficacy and cost-effectiveness. EXPAREL is a long-acting local anesthetic used for postoperative pain management. Some studies and healthcare professionals have questioned whether it provides significant benefits over traditional pain management options, given its higher cost. Additionally, there have been discussions about the marketing practices and clinical trial designs associated with the drug. These factors have contributed to ongoing debates within the medical community regarding its use.

Exparel is not an opioid. It is a long-acting local anesthetic used to manage pain, typically after surgery. It contains bupivacaine, which is a type of local anesthetic that works by blocking nerve signals in the body.

After receiving EXPAREL, it is advisable to avoid any activities that require full sensation or coordination until the effects of the medication have worn off. This includes driving or operating heavy machinery. Additionally, patients should avoid consuming alcohol and taking other medications that may cause drowsiness unless approved by their healthcare provider. It is also important to follow any specific post-procedure instructions provided by the healthcare team.

Exparel can potentially cause methemoglobinemia, a blood disorder where an abnormal amount of methemoglobin is produced, reducing the blood's ability to release oxygen to tissues.

EXPAREL is a local anesthetic. It is a formulation of bupivacaine, which is used to provide postsurgical analgesia by numbing the surgical area to reduce pain.