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This safety information outlines important considerations and potential risks associated with the use of loteprednol (Lotemax), a steroid eye medication. Please read carefully and consult your healthcare provider with any questions or concerns.

• Increased Eye Pressure (Glaucoma): Long-term use of steroid eye medications like loteprednol can increase eye pressure, potentially leading to glaucoma and nerve damage that affects vision. Notify your healthcare provider immediately if you experience persistent eye pain, discomfort, or vision changes. Regular check-ups with your provider are essential if you are using loteprednol for an extended period, especially if you have a history of glaucoma.

• Cataracts: Loteprednol can cause cataracts. If you notice worsening vision, or if lights seem to produce glares or halos, contact your provider promptly. While it is safe to use loteprednol for up to two weeks following cataract surgery, ensure regular follow-ups with your healthcare provider.

• Infections: Steroids can suppress the immune system, increasing the risk of fungal or viral eye infections. They may also alter infection symptoms, making them seem better or worse. If your eye condition worsens or does not improve within a few days of using loteprednol, consult your provider. If you finish your prescription and feel a need for a refill, a follow-up is necessary. This is particularly important if you have a history of herpes eye infections.

• Eye Damage: Steroid eye drops can thin parts of the eye like the cornea or sclera, leading to tears and more severe damage. The risk is higher if you have naturally thin corneas or sclera or if you use this medication long-term. After cataract surgery, loteprednol may slow healing and increase the risk of blebs (fluid-filled blisters) in the eye. Seek medical advice immediately if you experience eye pain, excessive tearing, or worsening vision.

• Contact Lens Use: Avoid wearing contact lenses if you have recently undergone eye surgery or are experiencing eye inflammation or allergies. Discuss with your provider whether you can wear contacts while using loteprednol. If allowed, remove soft contact lenses before applying the medication, as it contains benzalkonium chloride, which can damage lenses. Wait at least 15 minutes after applying loteprednol before reinserting your lenses.

Contraindications:

Do not use loteprednol (Lotemax) if you have:

• Viral, fungal, or mycobacterial eye infections.
• An allergy to loteprednol, other corticosteroids, or any of its ingredients.

If any of these conditions apply to you, consult your healthcare provider before using this medication.

When using this medication, some common side effects may occur, but they are usually mild and temporary. You might experience blurry vision, a burning sensation after applying the drops, itching, or a feeling like there's something in your eye. These symptoms often resolve on their own but consult with a healthcare provider if they persist or worsen.

There are other side effects that have been noted by some users, and while less common, they should not be ignored. These include eye inflammation, redness, headaches, runny nose, and throat irritation. Some individuals may experience increased eye pressure, slower healing, or even the development of cataracts. In very rare cases, the medication can lead to an eye infection, injury, or worse vision, which could manifest as eye pain, discomfort, or persistent changes in vision.

Serious allergic reactions to this medication are rare, but they can occur. Symptoms may include rash, severe dizziness, itching or swelling of the face, tongue, or throat, and difficulty breathing. Immediate medical attention is necessary if any of these symptoms arise. Additionally, this medication may mask or increase the risk of an eye infection, especially with prolonged use, so it's important to be vigilant for any new or worsening symptoms such as eye discharge or swelling. Always consult your healthcare provider if you notice any unusual or concerning effects.