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This medication comes with important safety warnings to help you understand the potential risks and necessary precautions. It is recommended to discuss any concerns with your healthcare provider to ensure safe usage.

• Hormonal Issues and Withdrawal: Prolonged use of topical hydrocortisone over large areas can cause adrenal suppression, where your body reduces its natural steroid hormone production. Abrupt discontinuation may lead to withdrawal symptoms such as skin swelling, rash, and burning. To minimize these risks, your healthcare provider will prescribe the lowest effective dose for the shortest duration. For long-term use or large applications, your adrenal function might need monitoring through lab tests. Always consult your provider before stopping the medication. Risks increase with prolonged use, excessive application, covering treated areas, and in young children.

• Elevated Blood Sugar: Extended use or application over large body areas can elevate blood sugar levels, potentially leading to diabetes. If you have diabetes, regular blood sugar monitoring is advised to ensure the medication remains safe for you. Report any increased thirst or urination to your provider. Risks are heightened with long-term or excessive use.

• Infections: Long-term use can increase the risk of developing skin or mouth infections. Do not use topical hydrocortisone on infected skin as it may worsen the condition. Contact your provider if you experience redness, swelling, pain, pus, or if symptoms persist beyond seven days, as these could indicate an infection. The risk grows with usage exceeding seven days.

• Skin Reactions: Misuse or extended use beyond your provider's guidance can lead to skin issues such as thinning, stretch marks, spider veins, burning, itching, irritation, dryness, inflamed hair follicles, color changes, or rashes. To avoid severe reactions, adhere to the prescribed dose and duration. Notify your provider of any new or worsening skin conditions. Risks are associated with excessive and inappropriate use.

Ensure you follow these guidelines and maintain communication with your healthcare provider for a safe treatment experience.

Locoid, a topical corticosteroid, is generally applied to the skin and has minimal systemic absorption when used as directed. However, under certain conditions—such as prolonged use, application over large areas, use on broken skin, or when covered with occlusive dressings—more of the medication may enter the bloodstream. This increased absorption can potentially lead to interactions with other medications.

For individuals managing diabetes, it's important to note that corticosteroids like Locoid can elevate blood sugar levels. This effect may reduce the effectiveness of antidiabetic medications, including Metformin. Therefore, if you're using Locoid and have diabetes, it's advisable to monitor your blood glucose levels more closely and consult your healthcare provider for any necessary adjustments to your diabetes treatment plan.

Additionally, using Locoid over large areas or for extended periods can suppress the body's natural steroid production, potentially leading to systemic side effects. To minimize this risk, it's recommended to use Locoid as prescribed, avoid applying it to large skin areas unless directed by a healthcare professional, and refrain from covering treated areas with bandages or dressings unless instructed.

Always inform your doctor about all medications and supplements you're currently taking to ensure safe and effective use of Locoid.