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This medication comes with important safety warnings to help you understand the potential risks and necessary precautions. It is recommended to discuss any concerns with your healthcare provider to ensure safe usage.

• Hormonal Issues and Withdrawal: Prolonged use of topical hydrocortisone over large areas can cause adrenal suppression, where your body reduces its natural steroid hormone production. Abrupt discontinuation may lead to withdrawal symptoms such as skin swelling, rash, and burning. To minimize these risks, your healthcare provider will prescribe the lowest effective dose for the shortest duration. For long-term use or large applications, your adrenal function might need monitoring through lab tests. Always consult your provider before stopping the medication. Risks increase with prolonged use, excessive application, covering treated areas, and in young children.

• Elevated Blood Sugar: Extended use or application over large body areas can elevate blood sugar levels, potentially leading to diabetes. If you have diabetes, regular blood sugar monitoring is advised to ensure the medication remains safe for you. Report any increased thirst or urination to your provider. Risks are heightened with long-term or excessive use.

• Infections: Long-term use can increase the risk of developing skin or mouth infections. Do not use topical hydrocortisone on infected skin as it may worsen the condition. Contact your provider if you experience redness, swelling, pain, pus, or if symptoms persist beyond seven days, as these could indicate an infection. The risk grows with usage exceeding seven days.

• Skin Reactions: Misuse or extended use beyond your provider's guidance can lead to skin issues such as thinning, stretch marks, spider veins, burning, itching, irritation, dryness, inflamed hair follicles, color changes, or rashes. To avoid severe reactions, adhere to the prescribed dose and duration. Notify your provider of any new or worsening skin conditions. Risks are associated with excessive and inappropriate use.

Ensure you follow these guidelines and maintain communication with your healthcare provider for a safe treatment experience.

When using this medication, some individuals may experience mild side effects such as stinging, burning, itching, irritation, dryness, or redness at the application site. These symptoms are usually temporary and should subside as your skin adjusts. However, if they persist or worsen, it's important to consult a healthcare professional. Additionally, some people might notice inflamed hair follicles, also known as folliculitis, which can manifest as small red bumps on the skin.

More persistent side effects include acne-like bumps, changes in skin color, rash or heat rash, and thinning or wrinkling of the skin. Stretch marks and unwanted hair growth may also occur. If these conditions develop, it is advisable to seek medical advice, especially if they are severe or cause concern.

In rare cases, the medication might be absorbed into the bloodstream, potentially leading to symptoms of excessive corticosteroid presence, such as unusual tiredness, weight loss, headache, swelling of ankles or feet, increased thirst or urination, and vision problems. Children and individuals using the medication over large skin areas for extended periods may be more susceptible. A very serious allergic reaction is rare but requires immediate medical attention if symptoms such as rash, severe dizziness, or trouble breathing appear. Always report any unlisted or concerning effects to your healthcare provider.