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While using this medication, you might experience common side effects such as dizziness, dry mouth, trouble sleeping, irritability, nausea, vomiting, diarrhea, or constipation. These are generally mild, but if they persist or worsen, it is important to inform your healthcare provider.

This medication may also cause an increase in blood pressure, so regular monitoring is advised. If you notice elevated blood pressure, consult your healthcare provider. Be alert for serious side effects like a fast or irregular heartbeat, mood changes (such as agitation or hallucinations), uncontrolled muscle movements, or changes in sexual interest. Should these occur, seek medical attention promptly.

In rare cases, the medication can lead to severe side effects, including severe headaches, speech difficulties, seizures, weakness on one side of the body, and vision changes. These warrant immediate medical assistance. Additionally, long-term use or combining it with other appetite suppressants may increase the risk of serious heart or lung problems, such as pulmonary hypertension or heart valve issues. If you experience chest pain, difficulty breathing with exercise, fainting, or swelling of the legs, stop using the medication and get medical help immediately.

Although a severe allergic reaction to this drug is rare, immediate medical attention is necessary if you develop symptoms like a rash, itching or swelling, severe dizziness, or difficulty breathing. Always report any unexpected side effects to your healthcare provider.

It's important to avoid combining this medication with certain drugs due to the risk of serious interactions. If you have used any appetite-suppressant drugs like diethylpropion or ephedra/ma huang in the past year, inform your doctor or pharmacist before starting this medication. Using MAO inhibitors with this drug can lead to dangerous, possibly life-threatening interactions. Do not take MAO inhibitors (including isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication and for two weeks before starting it. Consult your doctor for guidance on when to begin or discontinue this medication.

This drug may also interact with certain medications, including those for high blood pressure like guanethidine and methyldopa, phenothiazines such as prochlorperazine and chlorpromazine, and other stimulants like amphetamines, methylphenidate, or street drugs such as cocaine or MDMA ("ecstasy"). Additionally, inform your healthcare provider if you are taking other products that can cause drowsiness, such as opioid pain or cough relievers like codeine or hydrocodone, alcohol, marijuana (cannabis), sleep or anxiety medications like alprazolam, lorazepam, or zolpidem, muscle relaxants like carisoprodol or cyclobenzaprine, or antihistamines like cetirizine or diphenhydramine.

Check all medication labels, especially allergy or cough-and-cold products, since they may contain ingredients that cause drowsiness. Ask your pharmacist how to use these products safely. Some products might increase your heart rate or blood pressure, so inform your pharmacist about all the products you use, particularly cough-and-cold medicines or diet aids.

Caffeine can heighten the side effects of this medication. Limit your intake of caffeine-rich drinks like coffee, tea, and colas, as well as chocolate. This medication might also affect certain medical or lab tests, such as a brain scan for Parkinson's disease, potentially resulting in incorrect test results. Make sure all lab personnel and your doctors know you are taking this medication.