Opvee

Opvee Coupons & Savings Card – Discount Prices from $1477.48

Nalmefene, marketed as Opvee, is a nasal spray designed for the emergency treatment of opioid overdose in individuals aged 12 and older. This medication, approved by the FDA in May 2023, is primarily used to counteract serious symptoms of opioid overdose, such as extreme drowsiness, difficulties in awakening, and respiratory issues ranging from shallow breathing to complete cessation. Nalmefene is classified as an opioid antagonist, functioning by blocking opioid receptors in the brain, thereby reversing the effects of opioids. This action helps mitigate symptoms like reduced breathing and low blood pressure. It is crucial to administer nalmefene immediately in suspected overdose cases, even if uncertain, to prevent potential brain damage or death. Immediate medical attention is recommended after the first dose, as symptoms could reappear. Currently, Opvee is available by prescription and may cause side effects including nasal discomfort, headache, and nausea.
Our Opvee coupons are free to use. You can print the coupon, email it to yourself, or receive the Opvee coupon via text message. To get your free discount, show the pharmacist your Opvee savings card which has the discounted coupon price. Use our filters below to edit the prescription box to match your needs. The Opvee prices will update based on your prescription needs. Above our Opvee coupons, you can change the location to see pharmacy prices in other areas. Our prescription discount card will update online with the specific pharmacy costs associated with your edits. Be sure to text, email, or print the Opvee savings card code that you need after editing the prescription box and location field. Show the discount card to your pharmacist before paying.

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2.7MG/0.1ML, Opvee (30 Solutions)

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Opvee savings card

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Price history for Opvee

30 Solutions, 2.7MG/0.1ML

Average retail price for Opvee

Average SaveHealth price for Opvee

Our price history data is based on aggregated prescription data collected from participating pharmacies in America. Our prescription data updates daily to reflect the latest price changes. If you notice a missing data point, it means there wasn't sufficient data available to generate a monetary value for that date.

*Retail prices are based on pharmacy claims data, and may not be accurate when we don't have enough claims.

Opvee dosage forms

Use our Opvee 2.7MG/0.1ML coupon with prices from $1477.48 for 30 Solutions.
DosageQuantityPrice fromPer unit
2.7MG/0.1ML30 Solutions$1477.48$49.25

Opvee Warnings

The safety information below outlines critical warnings associated with the use of Opvee (nalmefene). It is essential to understand these risks and follow the advised precautions. If you have any concerns, please consult your healthcare provider.

  • Risk of Recurrent Opioid Overdose Symptoms: Even after initial successful response to Opvee (nalmefene), symptoms of an opioid overdose may resurface, particularly in cases involving multiple types of opioids, where some may have longer-lasting effects. It is crucial to seek medical assistance immediately after administering the first dose and continuously monitor the individual. If symptoms do not improve within 2 to 5 minutes, administer an additional dose using a new nasal spray in the other nostril. This is particularly important when long-acting opioids are involved.

  • Need for Repeated Doses: In cases involving opioids with mixed receptor activities, such as buprenorphine, Opvee (nalmefene) may require multiple doses to effectively counteract the drug. Ensure each additional dose is delivered with a new nasal spray. This precaution is necessary for individuals taking pain medications containing buprenorphine or pentazocine.

  • Opioid Withdrawal Symptoms: Administration of Opvee (nalmefene) can trigger sudden opioid withdrawal, characterized by symptoms such as pain, body aches, diarrhea, rapid heartbeat, fever, sweating, nausea, vomiting, irritability, and trembling. This risk is heightened in individuals who regularly use opioids, have recently undergone surgery, or are infants under one month old who have been exposed to opioids. Immediate notification of a healthcare provider is advised, along with close monitoring of symptoms.

Currently, there are no specified contraindications for the use of Opvee (nalmefene).

Opvee Side Effects

When taking this medication, some common side effects may occur, which are generally mild and manageable. You might experience nasal discomfort or a stuffy nose, headaches, nausea, dizziness, hot flushes, or vomiting. These effects are often temporary, but if they persist or worsen, consulting your healthcare provider is advisable. Additionally, some people might feel tired, experience throat irritation, or notice nose pain. In rare cases, serious side effects can occur, necessitating prompt medical attention. Allergic reactions, although uncommon, are serious and can manifest as rash, swelling (particularly of the face, tongue, or throat), severe dizziness, or breathing difficulties. Immediate medical help is crucial if you experience these symptoms. For those who have been using opioids regularly, this medication might trigger withdrawal symptoms. These symptoms could include anxiety, irritability, body aches, fast heartbeat, sweating, vomiting, shakiness, and increased blood pressure. Should you notice any of these severe reactions, seeking urgent medical care is imperative. Always stay vigilant and informed about how your body responds to new medications.

Opvee Interactions

Opvee (nalmefene) is an opioid antagonist used for the emergency treatment of known or suspected opioid overdoses. While it is primarily designed to counteract the effects of opioids, it's important to be aware of potential interactions with other medications and health conditions.

Drug Interactions:

Opvee has been identified to interact with certain medications, including:

  • Flumazenil: This interaction is considered minor.

  • Glimepiride: A moderate interaction exists; caution is advised.

  • Levomethadyl acetate: Moderate interaction; use under special circumstances.

  • Methylnaltrexone: Moderate interaction; consult healthcare provider.

  • Naldemedine: Moderate interaction; monitor closely.

  • Naloxegol: Moderate interaction; assess risk and consider alternatives.

These interactions can affect how Opvee or the other medications work, potentially leading to reduced effectiveness or increased side effects. It's crucial to inform your healthcare provider about all medications you're currently taking, including over-the-counter drugs and supplements, to ensure safe and effective use of Opvee.

Disease Interactions:

Individuals with hepatic (liver) or renal (kidney) dysfunction should exercise caution when using Opvee. These conditions can influence how the body processes medications, potentially altering the effectiveness and safety of Opvee. If you have liver or kidney issues, discuss with your healthcare provider whether Opvee is appropriate for you and if any dosage adjustments are necessary.

Important Considerations:

  • Opioid Withdrawal: In opioid-dependent individuals, Opvee may precipitate withdrawal symptoms such as body aches, fever, sweating, runny nose, sneezing, goosebumps, yawning, nausea or vomiting, nervousness, restlessness or irritability, shivering or trembling, abdominal cramps, weakness, and increased blood pressure. These symptoms can be uncomfortable and may require medical attention.

  • Cardiovascular Effects: In patients with pre-existing heart conditions, the use of Opvee can lead to adverse cardiovascular events, including rapid heart rate, changes in blood pressure, and in rare cases, more severe heart-related issues. Monitoring by a healthcare professional is recommended in such cases.

Always consult with your healthcare provider before starting or stopping any medication, and ensure they are aware of your complete medical history to minimize the risk of adverse interactions and side effects.

Opvee FAQs
What is the difference between Narcan and Opvee?

Narcan and Opvee are both medications used to reverse opioid overdoses, but they differ in their active ingredients and administration methods. Narcan contains naloxone, which is typically administered as a nasal spray or injection. Opvee, on the other hand, contains nalmefene and is administered as a nasal spray. Both medications work by binding to opioid receptors in the brain, reversing the effects of opioids, and restoring normal breathing in individuals experiencing an overdose.

Opvee is used as an opioid receptor antagonist for the emergency treatment of known or suspected opioid overdose. It works by rapidly reversing the effects of opioids, including respiratory depression, sedation, and hypotension. It is typically administered in situations where immediate medical intervention is required to prevent potentially life-threatening consequences of an overdose.

Opvee is not available over the counter. It is a prescription medication and requires a healthcare provider's authorization for use.

Yes, Opvee, which contains the active ingredient nalmefene, is classified as a controlled substance. It is typically used in the management of opioid overdose.

The cost of Opvee can vary depending on factors such as the pharmacy, location, and whether the patient has insurance coverage. It is recommended to check with local pharmacies or the patient's insurance provider for the most accurate and up-to-date pricing information.