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Antidepressant medications are commonly prescribed to address conditions like depression and other mental or mood disorders. While they can significantly reduce the risk of suicidal thoughts and offer other important therapeutic effects, it is important to note that a small subset of individuals, particularly those under the age of 25, might experience an increase in depressive symptoms or the emergence of suicidal thoughts or actions.

Key Considerations:

• Discuss the potential risks and benefits of antidepressants with a healthcare provider, especially if the patient is under 25, regardless of whether the treatment is for a mental or mood-related condition.
• Immediately report to a healthcare professional any signs of worsening depression, new or intensified psychiatric symptoms, unusual behavioral changes, or suicidal thoughts or behaviors.

• Pay close attention to any of the following symptoms when initiating a new antidepressant or modifying the dosage: increased anxiety, panic attacks, difficulties sleeping, irritability, aggressive or hostile feelings, impulsive behavior, severe restlessness, or extremely rapid speech.

  It is crucial to remain vigilant for these symptoms to ensure timely intervention and effective management of any adverse effects.

When taking this medication, you might experience some mild side effects such as nausea, drowsiness, dizziness, trouble sleeping, loss of appetite, weakness, dry mouth, sweating, blurred vision, and yawning. These effects are usually manageable, but if they persist or worsen, consult your healthcare provider.

Some side effects require immediate attention. Contact your doctor if you notice shaking, restlessness, inability to stay still, reduced sexual interest or ability, numbness or tingling, easy bruising or bleeding, irregular heartbeat, muscle spasms, or seizures. These are considered more serious and should not be ignored.

Seek urgent medical help if you experience very serious side effects like black stools, vomit resembling coffee grounds, eye pain or swelling, widened pupils, or vision changes. These symptoms could indicate significant health issues.

This medication may rarely cause serotonin syndrome, especially if combined with other serotonin-enhancing drugs. Symptoms include fast heartbeat, hallucinations, loss of coordination, severe dizziness, nausea, vomiting, diarrhea, muscle twitching, fever, and unusual agitation. If you observe any of these, get immediate medical assistance.

Additionally, a rare but serious condition that may occur in males is a prolonged erection lasting more than four hours, which requires prompt medical intervention to prevent long-term damage. Severe allergic reactions are also rare but serious, characterized by rash, itching, swelling of the face, tongue, or throat, severe dizziness, and difficulty breathing. Immediate medical attention is necessary if these occur.

This is not an exhaustive list of side effects. If you experience any other unexpected symptoms, reach out to your healthcare provider for guidance.

Some medications that can interact with this drug include Thioridazine, and others that may increase bleeding or bruising risk, such as antiplatelet drugs like Clopidogrel, NSAIDs like Ibuprofen or Naproxen, and anticoagulants like Dabigatran or Warfarin. Taking Aspirin with this drug may also heighten bleeding risk. However, if your doctor has advised you to take low-dose aspirin (typically 81-162 milligrams daily) to help prevent a heart attack or stroke, continue doing so unless instructed otherwise by your doctor. Consult your doctor or pharmacist for more guidance.

This drug can also slow the elimination of other medications from your body, potentially altering their effectiveness. Affected drugs include Atomoxetine, phenothiazines, Pimozide, Risperidone, Tamoxifen, Tetrabenazine, certain antiarrhythmics like Propafenone or Flecainide, and tricyclic antidepressants like Desipramine or Amitriptyline.

Using MAO inhibitors with this medication can lead to a dangerous, possibly fatal, interaction. Avoid MAO inhibitors (such as isocarboxazid, Linezolid, Metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, Rasagiline, safinamide, Selegiline, and Tranylcypromine) during treatment with this drug. Most MAO inhibitors should also be avoided for two weeks before and after using this medication. Consult your doctor to determine when to start or stop this medication.

The risk of serotonin syndrome or toxicity increases if you are taking other drugs that elevate serotonin levels. These include street drugs like MDMA/"ecstasy," St. John's wort, certain antidepressants such as other SSRIs like Citalopram or Fluoxetine, SNRIs like Duloxetine or Venlafaxine, and Tryptophan. The likelihood of serotonin syndrome/toxicity may be higher when beginning or increasing the dose of these drugs.

Inform your doctor or pharmacist if you are using other products that cause drowsiness, including alcohol, marijuana (cannabis), antihistamines like Cetirizine or diphenhydramine, sleep or anxiety medications like Alprazolam, Diazepam, or Zolpidem, muscle relaxants, and opioid pain relievers like codeine.

Always check the labels on all your medications (such as those for allergies or cough-and-cold) as they may contain ingredients that cause drowsiness. Ask your pharmacist how to use these products safely.

This medication might interfere with certain medical or lab tests (like a brain scan for Parkinson's disease), possibly leading to inaccurate results. Ensure that lab personnel and all your healthcare providers are aware that you are using this drug.