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Antidepressant medications are prescribed to manage conditions like depression and various mental or mood disorders. They can play a crucial role in reducing suicidal thoughts or attempts and offer significant benefits. Nevertheless, research indicates that a small segment of individuals, particularly those under 25, might experience an increase in depression symptoms or the emergence of suicidal thoughts when using antidepressants, regardless of the condition being treated.

Here are some important points to consider:

• Discuss the potential risks and advantages of antidepressant therapy with your healthcare provider, especially if you are younger than 25, even if the therapy is unrelated to mental or mood disorders.
• Promptly inform your doctor if you observe any deterioration in depression or other psychiatric symptoms, notice unusual behavioral changes, or experience new or worsening mental or mood changes, such as heightened anxiety, panic attacks, difficulty sleeping, irritability, feelings of hostility or anger, impulsive behavior, severe restlessness, or unusually rapid speech.
• Vigilance is particularly important when beginning a new antidepressant or adjusting the dosage.

These precautions help ensure safe and effective use of antidepressants.

You may experience some common side effects such as nausea, dry mouth, loss of appetite, tiredness, drowsiness, sweating, blurred vision, and yawning. These effects are typically mild, but if they persist or worsen, it's important to inform your healthcare provider.

Be aware of more serious side effects, which require prompt attention. These include shaking (tremor), decreased interest in sex, changes in sexual ability, or easy bleeding/bruising. If you notice any of these, contact your healthcare provider immediately.

In rare instances, very serious side effects may occur. Seek urgent medical help if you experience fainting, fast or irregular heartbeat, black stools, vomit resembling coffee grounds, seizures, eye pain/swelling/redness, widened pupils, or vision changes like seeing rainbows around lights at night.

This medication can increase serotonin levels, which may lead to a rare but serious condition known as serotonin syndrome. If you experience symptoms such as a fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, or unusual agitation/restlessness, seek medical assistance immediately.

Additionally, although rare, males may experience a painful or prolonged erection lasting 4 or more hours. This requires immediate medical attention to prevent permanent issues.

Allergic reactions to this medication are uncommon but can be serious. Get medical help right away if you notice symptoms like rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, or trouble breathing.

If you notice any other effects not listed here, please consult your healthcare provider for advice.

When taking this medication, be aware of possible interactions with other drugs. Medications that may increase the risk of bleeding or bruising include antiplatelet drugs like Clopidogrel, NSAIDs such as Ibuprofen or Naproxen, and anticoagulants like Dabigatran or Warfarin. Aspirin can also heighten bleeding risk, but if your doctor has advised you to take low-dose aspirin (81-162 mg daily) for heart attack or stroke prevention, continue unless instructed otherwise. Consult your doctor or pharmacist for guidance.

Avoid using MAO inhibitors (like isocarboxazid, Linezolid, and others) with this medication, as this can lead to a serious, potentially fatal interaction. Typically, MAO inhibitors should not be used for two weeks before and after this treatment. Speak with your healthcare provider about when to start or stop these medications.

The likelihood of serotonin syndrome, a potentially dangerous condition, increases if you're taking other serotonin-increasing substances. These include illicit drugs like MDMA, St. John's wort, certain antidepressants, and Tryptophan. The risk is higher when starting or increasing the dosage of these medications.

Inform your doctor or pharmacist about any other products you take that cause drowsiness, such as alcohol, cannabis, antihistamines, sleep or anxiety medications, muscle relaxants, and opioid pain relievers. Additionally, check the labels on all your medications, including allergy and cold products, for drowsiness-causing ingredients. Consult your pharmacist on safe usage.

Other drugs may affect heart rhythm (QT prolongation), including Amiodarone, Pimozide, and others. Since citalopram is similar to Escitalopram, avoid using both medications simultaneously. This drug may also interfere with certain medical tests, potentially leading to incorrect results, so ensure all healthcare providers and lab personnel are aware of your medication use.