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Taking this medication can sometimes lead to dizziness, dry mouth, trouble sleeping, irritability, nausea, vomiting, diarrhea, or constipation. These are generally mild and may go away on their own; however, if they persist or worsen, it is important to consult with your healthcare provider. Monitoring your blood pressure is advisable, as this drug may cause an increase; report elevated readings to your healthcare provider.

Serious side effects, though less common, require prompt attention. These include rapid or irregular heartbeat, changes in mood or mental state such as agitation or hallucinations, involuntary muscle movements, and shifts in sexual interest or ability. Very serious adverse effects like intense headaches, difficulty speaking, seizures, sudden weakness on one side of the body, or vision changes should be addressed immediately by seeking medical help.

In rare instances, this medication might cause severe lung or heart issues, such as pulmonary hypertension or heart valve problems, especially with prolonged use or in combination with other appetite suppressants. Symptoms like chest pain, breathing difficulties during exercise, reduced exercise capacity, fainting, or swelling of the legs or feet necessitate stopping the medication and contacting your healthcare provider promptly.

Although rare, allergic reactions can occur. Seek emergency medical attention if you experience symptoms such as rash, itching, swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing. If you observe any side effects not mentioned here, reach out to your healthcare provider for guidance.

Certain substances can interact with this medication. These include stimulants like amphetamines, Methylphenidate, and recreational drugs such as cocaine or MDMA ("ecstasy"). This medication should not be combined with specific drugs due to the risk of serious interactions. Inform your doctor if you have used appetite suppressants like phentermine or ephedra/ma huang in the past year before starting this treatment.

Using MAO inhibitors with this medication can lead to a dangerous, possibly life-threatening reaction. Do not take MAO inhibitors, including isocarboxazid, Linezolid, Metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, Rasagiline, safinamide, Selegiline, and Tranylcypromine, while on this medication. Most MAO inhibitors should be avoided for at least two weeks before starting this medication. Consult your doctor for guidance on when to begin or discontinue this treatment.

Additionally, inform your healthcare provider if you're using other products that cause drowsiness, such as opioid pain relievers (e.g., codeine, hydrocodone), alcohol, marijuana (cannabis), sleep or anxiety medications (e.g., Alprazolam, Lorazepam, Zolpidem), muscle relaxants (e.g., Carisoprodol, Cyclobenzaprine), or antihistamines (e.g., Cetirizine, diphenhydramine).

Read labels on all your medications, especially allergy or cough-and-cold products, as they may contain drowsiness-inducing ingredients. Consult your pharmacist about safe usage. Some products may increase heart rate or blood pressure. Discuss any products you are using with your pharmacist, particularly cough-and-cold remedies or diet aids.

Lastly, Caffeine can amplify the side effects of this medication. Avoid excessive consumption of caffeine-rich beverages like coffee, tea, or colas, and limit chocolate intake.