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Azathioprine

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generic Imuran, Azasan

Azathioprine, also known by the brand name Imuran, is a medication primarily used to prevent organ rejection in individuals who have undergone a kidney transplant and to treat rheumatoid arthritis. As an immunosuppressant, azathioprine functions by weakening the immune system. This is crucial after a kidney transplant to help the body accept the new organ and prevent rejection. In the case of rheumatoid arthritis, it helps to prevent the immune system from attacking the joints, thereby reducing inflammation and joint damage. While azathioprine is effective, it is not typically the first choice due to its potential side effects. Initially, the medication may be administered via injection until oral intake is possible. It's important to discuss the risks and benefits of azathioprine with a healthcare provider, particularly for children and young adults. Always consult your doctor, nurse, or pharmacist before starting any new medication or treatment regimen to ensure it is safe and suitable for your condition.
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100MG, Azathioprine (30 Solution Reconstituteds)

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CVS

$7398.00

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$7766.01

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$7777.00

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Azathioprine savings card

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Azathioprine dosage forms

The average cost for 30 Solution Reconstituteds of Azathioprine (generic Imuran, Azasan) at 100MG is $7398 with a free coupon. This is 27.50% off the average retail price of $26900.22
DosageQuantityPrice fromPer unit
100MG30 Solution Reconstituteds$7398$246.6

Azathioprine Warnings

Azathioprine, also known as Imuran, is associated with several important safety warnings and precautions. Patients using this medication should be aware of the potential risks and necessary precautions to ensure safe use. It is essential to consult with a healthcare provider if any concerns arise.

  • Cancer Risk: There is an increased risk of developing certain cancers, including lymphoma and skin cancer, particularly for those undergoing organ transplants and children or young adults treated for bowel diseases like Crohn's disease or ulcerative colitis. Protect your skin by limiting sun exposure, wearing protective clothing, and using sunscreen. Report any unusual skin changes, new growths, or swollen lymph nodes to your doctor immediately.

  • Blood Cell Reduction: Azathioprine may suppress bone marrow function, leading to decreased levels of red and white blood cells and platelets, which can cause anemia, increased susceptibility to infections, and easy bruising or bleeding. Regular blood tests will be conducted by your healthcare provider to monitor your blood cell levels. Notify your doctor if you experience symptoms such as unusual fatigue, pale skin, persistent sore throat, fever, chills, or easy bruising/bleeding.

  • Infection Susceptibility: Long-term use of azathioprine can heighten the risk of serious infections. It is advisable to avoid contact with sick individuals and practice good hygiene, such as frequent handwashing. Avoid live vaccines, such as varicella, yellow fever, or MMR, as the medication may weaken your immune response. Seek medical attention if you experience sudden muscle weakness, speech or vision changes, or develop a fever.

  • Liver Health: The medication may cause elevated liver enzyme levels, indicating potential liver damage, typically within the first six months of treatment. If liver issues arise, cessation of the medication usually resolves the problem.

In case of any unusual or severe symptoms, contact your healthcare provider immediately for further guidance. Always keep all medical and laboratory appointments to ensure ongoing safety while using azathioprine.

Azathioprine Side Effects

Common side effects:

  • nausea
  • vomiting
  • temporary hair loss

Less common but important to monitor:

  • leukopenia
  • higher susceptibility to infections
  • fatigue
  • muscle pain
  • persistent fever
  • unexplained bleeding or bruising
  • significant liver damage
  • worsening joint or muscle pain
  • ongoing nausea or vomiting
  • abdominal pain
  • dark urine
  • yellowing of the skin or eyes

Serious side effects:

  • progressive multifocal leukoencephalopathy (PML)
  • severe allergic reaction

Azathioprine Interactions

Interactions with high risk of serious adverse effects and should be avoided:

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

Interactions with low risk that usually do not require a change in therapy:

Azathioprine FAQs
What is the drug azathioprine used for?

Azathioprine is used to suppress the immune system. It is commonly prescribed to prevent organ rejection in transplant patients and to treat autoimmune conditions such as rheumatoid arthritis, lupus, and inflammatory bowel diseases like Crohn's disease and ulcerative colitis.

Azathioprine is not commonly associated with weight gain as a side effect. However, individual responses to medication can vary. If there are concerns about weight changes while taking azathioprine, it is advisable to consult with a healthcare provider for personalized advice and evaluation.

Azathioprine is not classified as a traditional chemotherapy drug. It is an immunosuppressant medication primarily used to prevent organ transplant rejection and to treat autoimmune conditions such as rheumatoid arthritis and inflammatory bowel disease. While it does affect the immune system, its mechanism and use differ from those of conventional chemotherapy drugs used to treat cancer.

While taking azathioprine, one should avoid the following:1. Live Vaccines: Avoid receiving live vaccines, as azathioprine can weaken the immune system, making live vaccines potentially harmful.2. Sun Exposure: Limit exposure to sunlight or UV light, as azathioprine can increase sensitivity to the sun, raising the risk of skin cancer.3. Alcohol Consumption: Minimize alcohol intake, as both azathioprine and alcohol can affect liver function.4. Certain Medications: Avoid taking medications that can interact with azathioprine, such as allopurinol, without consulting a healthcare provider.5. Infection Risks: Be cautious of situations that increase the risk of infections, as azathioprine can lower the body's ability to fight infections.It is important to follow the healthcare provider's advice and report any unusual symptoms or concerns while on azathioprine.

Azathioprine is not typically classified as a chemotherapy drug. It is an immunosuppressant medication primarily used to prevent organ rejection in transplant patients and to treat autoimmune conditions such as rheumatoid arthritis and inflammatory bowel disease.