Acetazolamide

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Acetazolamide is a medication designed to prevent and alleviate altitude sickness symptoms, such as headaches, fatigue, nausea, dizziness, and shortness of breath, which may occur when rapidly ascending to high altitudes (typically over 10,000 feet or 3,048 meters). It is especially beneficial when a gradual ascent isn't possible. The most effective ways to avoid altitude sickness include ascending slowly, pausing for 24 hours to acclimate, and taking it easy during the first couple of days. Additionally, acetazolamide can be used alongside other treatments to manage increased eye pressure associated with certain types of glaucoma, as it reduces fluid production in the eye. This drug, part of the carbonic anhydrase inhibitors class, is also prescribed to reduce fluid retention (edema) due to heart failure or specific medications. Since its effectiveness may decrease over time, acetazolamide is generally prescribed for short-term use. Furthermore, it has been utilized in combination with other drugs to treat certain seizure types, including petit mal and unlocalized seizures.
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125MG, Acetazolamide (30 Tablets)

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CVS

$19.71

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$6.68

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$7.08

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$15.00

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Acetazolamide savings card

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Acetazolamide dosage forms

The average cost for 30 Tablets of Acetazolamide () at 125MG is $6.68 with a free coupon. This is 10.60% off the average retail price of $63
DosageQuantityPrice fromPer unit
125MG30 Tablets$6.68$0.22
250MG30 Tablets$8$0.27

Acetazolamide Side Effects

When starting this medication, you might experience mild side effects like dizziness, lightheadedness, or increased urination, particularly in the initial days as your body adjusts. Other common effects include blurred vision, dry mouth, drowsiness, loss of appetite, nausea, vomiting, diarrhea, and changes in taste. These usually improve over time, but if they persist or worsen, it's important to inform your healthcare provider.

To minimize dizziness or lightheadedness, try standing up slowly from sitting or lying down. It's reassuring to know that many people using this medication do not experience serious side effects.

However, you should be vigilant for severe reactions and seek immediate medical attention if you experience symptoms such as tingling in the hands or feet, hearing loss, ringing in the ears, unusual fatigue, easy bruising or bleeding, irregular heartbeat, muscle cramps or pain, new or worsening eye pain, vision changes, mood changes like confusion or difficulty concentrating, or signs of liver or kidney issues. These may include persistent nausea, vomiting, abdominal pain, yellowing of the skin or eyes, dark urine, painful urination, or bloody urine. Additionally, be alert for signs of infection, such as a persistent sore throat, fever, or chills.

Though very rare, severe allergic reactions can occur. Urgent medical help is necessary if you notice symptoms like rash, itching, swelling, severe dizziness, or difficulty breathing. Always report any unlisted effects to your healthcare provider.

Interactions

This medication can interact with several other products, including Lithium, Memantine, Methenamine, and Orlistat. It can also interact with certain seizure medications like Topiramate and Zonisamide. Be sure to check the labels of all your medications, as some may contain Aspirin or aspirin-like drugs (salicylates). Taking large doses of these with your medication could lead to serious side effects. If your doctor has advised you to take low-dose aspirin (usually 81-162 milligrams daily) to prevent heart attacks or strokes, continue taking it unless your doctor instructs otherwise. Consult your doctor or pharmacist for more information. Additionally, some products could worsen swelling. Inform your pharmacist about all products you are using and seek advice on safe usage, particularly with NSAIDs like Ibuprofen or Naproxen. This medication might also affect certain lab tests, potentially causing inaccurate results. Ensure all healthcare providers and lab personnel are aware you are taking this medication.
Acetazolamide FAQs
What does acetazolamide do to the brain?

Acetazolamide primarily affects the brain by reducing the production of cerebrospinal fluid (CSF), which can help decrease intracranial pressure. It is often used to treat conditions like idiopathic intracranial hypertension. Additionally, acetazolamide can alter the pH balance in the brain, which may have effects on neuronal activity and is sometimes used in the management of certain types of seizures.

The most severe adverse effect of acetazolamide is the potential for metabolic acidosis. This condition occurs when there is an imbalance in the body's acid-base levels, leading to an accumulation of acid or a loss of bicarbonate. It is important for patients taking acetazolamide to be monitored for signs of metabolic acidosis and other potential side effects.

Acetazolamide primarily acts as a diuretic and carbonic anhydrase inhibitor. It does not have a direct effect on the heart. However, by promoting diuresis, it can lead to a reduction in blood volume, which may indirectly decrease cardiac workload and blood pressure. This can be beneficial in conditions where reducing fluid overload is necessary. It is important for patients to follow their healthcare provider's instructions when using acetazolamide, as it can affect electrolyte balance and other bodily functions.

Acetazolamide is used to treat conditions such as glaucoma, certain types of seizures, altitude sickness, and fluid retention due to congestive heart failure. It works by reducing the production of certain fluids in the body, which helps decrease pressure and fluid buildup.

Acetazolamide is not banned; however, it is a medication that is sometimes restricted in certain sports. It is on the World Anti-Doping Agency's list of prohibited substances because it can be used as a masking agent to hide the presence of other performance-enhancing drugs. In medical practice, acetazolamide is used for specific conditions such as glaucoma, altitude sickness, and certain types of seizures.