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The safety information below outlines the critical warnings and precautions associated with the use of this medication. It's essential to review these details and discuss any concerns with your healthcare provider.

• Low Blood Pressure and Kidney Injury: Torsemide is designed to eliminate excess fluid from your body, but this can sometimes lead to excessively low blood pressure or dehydration, which may result in kidney injury. Certain drugs, such as nonsteroidal anti-inflammatory drugs (NSAIDs), can increase the risk of kidney damage. Inform your healthcare provider about all medications you're currently taking before starting torsemide. Regular blood tests will be conducted to monitor your kidney function. Report to your provider if you frequently feel lightheaded or dizzy, as your dosage may need adjustment. If you notice a significant decrease in urination or darker urine, contact your healthcare provider immediately, as these could indicate kidney issues. Be cautious if you're taking other blood pressure-lowering medications, drugs that may harm the kidneys, or consuming alcohol.

• Electrolyte and Blood Sugar Changes: Torsemide can alter your body's levels of electrolytes such as sodium, potassium, magnesium, and calcium. Notify your healthcare provider if you experience symptoms like dry mouth, fatigue, dizziness, muscle pain or cramps, rapid heart rate, vomiting, or nausea, as these may indicate an electrolyte imbalance. The risk is heightened if you have existing kidney issues, are on medications affecting electrolytes, or are exposed to hot weather.

• Hearing Issues: There is a possibility of experiencing ringing in the ears or hearing loss while on torsemide. This condition is typically temporary and resolves after discontinuing the medication, although rare cases of permanent hearing damage have been reported. The risk increases with higher doses of torsemide or existing kidney problems. Discuss any concerns about potential hearing problems with your healthcare provider.

Contraindications: Do not use this medication if any of the following conditions apply to you, as it may lead to serious health risks. Always consult with your healthcare provider beforehand.

• Previous allergic reactions to torsemide
• Allergy to povidone (related to generic torsemide)
• Inability to urinate
• Hepatic coma (a serious condition involving confusion or loss of brain function due to liver issues)

Common side effects:

• Dizziness
• Increased urination

Less common but important to monitor:

• Muscle weakness
• Rash
• Belly pain
• Changes in vision
• Reduced appetite

Serious side effects:

• Severe dehydration and electrolyte imbalance
• Irregular heartbeat
• Low blood pressure
• Serious skin reaction
• Allergic reaction

Interactions with high risk of serious adverse effects and should be avoided:

• Desmopressin

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Lithium
• Ibuprofen
• Naproxen
• NSAIDs (Nonsteroidal Anti-inflammatory Drugs)

Interactions with low risk that usually do not require a change in therapy:

• ACE inhibitors (such as Lisinopril, Enalapril)
• Licorice
• Ginseng