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It is important to follow all safety guidelines and warnings while using this medication to ensure its effectiveness and your safety. Below are key considerations and precautions to keep in mind:

• Do not abruptly stop taking the medication: Discontinuing this drug suddenly may worsen certain conditions. Some individuals who have stopped similar medications suddenly have experienced chest pain, heart attack, or irregular heartbeat. If discontinuation is necessary, your doctor will guide you in gradually reducing the dosage over 1 to 2 weeks. During this period, limit physical activity to reduce heart strain. Seek immediate medical attention if you experience chest pain, jaw/neck/arm pain, unusual sweating, difficulty breathing, or a rapid/irregular heartbeat.

• Heart failure risk: Pindolol may exacerbate heart failure symptoms, particularly if pre-existing symptoms are not well-managed. It is generally avoided in severe heart failure cases. Consult your healthcare provider if you notice swelling in your feet or ankles, an irregular pulse, or breathing difficulties while lying down or exercising.

• Heart attack or chest pain risk: Abrupt cessation of pindolol can lead to or worsen chest pain and potentially cause a heart attack, especially in individuals with coronary artery disease, diagnosed or otherwise. Always consult your doctor before stopping this medication to ensure a safe and gradual discontinuation plan.

• Breathing difficulties: Pindolol may constrict lung vessels, complicating breathing for individuals with conditions such as asthma or emphysema. Inform your doctor of any respiratory issues before starting pindolol, as it can interfere with medications used to treat these conditions.

• Surgical considerations: If undergoing major surgery with anesthesia, inform your surgeon that you are taking pindolol. They might recommend stopping the medication temporarily or administer drugs to counteract its effects during surgery.

• Masked symptoms of low blood sugar: Pindolol can obscure low blood sugar symptoms, except for sweating. If you are diabetic and using blood sugar-lowering medications like glipizide or insulin, discuss monitoring strategies with your doctor when starting pindolol.

• Masked symptoms of hyperthyroidism: For those with overactive thyroid, pindolol might mask signs such as a rapid heartbeat. Do not discontinue the medication abruptly without consulting your healthcare provider, as it can exacerbate thyroid issues.

Contraindications:

• This medication should not be used by individuals with asthma or certain severe heart conditions where symptoms are uncontrolled. Always consult with a healthcare provider to ensure safety before commencing treatment.

In case of any concerns or need for clarification, it is crucial to discuss them with your healthcare provider for personalized advice and guidance.

Common side effects:

• dizziness
• weakness
• nausea
• trouble sleeping
• muscle pain
• fatigue
• nervousness

Less common but important to monitor:

• swelling
• joint pain
• bizarre dreams
• shortness of breath
• cold hands and feet

Serious side effects:

• symptoms of heart failure (shortness of breath, unusual tiredness, swelling in the legs, sudden weight gain)
• bronchospasm (chest tightness and difficulty breathing)
• allergic reaction (rash, severe dizziness, trouble breathing)

Interactions with high risk of serious adverse effects and should be avoided:

• Thioridazine

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• Epinephrine
• Fingolimod
• Albuterol
• Bupropion
• Ceritinib
• Clonidine
• Crizotinib
• Diltiazem
• Dronedarone
• Fenoldopam
• Formoterol
• Indacaterol
• Iobenguane I 131
• Iohexol
• Lacosamide
• Levalbuterol
• Olodaterol
• Oxymetazoline
• Ponesimod
• Rivastigmine
• Salmeterol
• Siponimod
• Terbutaline
• Verapamil
• Vilanterol

Interactions with low risk that usually do not require a change in therapy:

• Acarbose
• Aceclofenac
• Acemetacin
• Acetyldigoxin
• Albiglutide
• Alfuzosin
• Alogliptin
• Amtolmetin Guacil
• Arbutamine
• Aspirin
• Bromfenac
• Bufexamac
• Bunazosin
• Canagliflozin
• Celecoxib
• Chlorpropamide
• Choline Salicylate
• Clonixin
• Dapagliflozin
• Deslanoside
• Dexibuprofen
• Dexketoprofen
• Diclofenac
• Diflunisal
• Digitoxin
• Digoxin
• Dipyrone
• Doxazosin
• Droxicam
• Dulaglutide
• Empagliflozin
• Ertugliflozin
• Etodolac
• Etofenamate
• Etoricoxib
• Exenatide
• Felbinac
• Fenoprofen
• Fepradinol
• Feprazone
• Floctafenine
• Flufenamic Acid
• Flurbiprofen
• Glimepiride
• Glipizide
• Glyburide
• Ibuprofen
• Indomethacin
• Insulin Aspart, Recombinant
• Insulin Degludec
• Insulin Detemir
• Insulin Glargine, Recombinant
• Insulin Glulisine
• Insulin Human Inhaled
• Insulin Human Isophane (NPH)
• Insulin Human Regular
• Insulin Lispro, Recombinant
• Ketoprofen
• Ketorolac
• Linagliptin
• Liraglutide
• Lixisenatide
• Lornoxicam
• Loxoprofen
• Lumiracoxib
• Meclofenamate
• Mefenamic Acid
• Meloxicam
• Metformin
• Metildigoxin
• Mibefradil
• Miglitol
• Morniflumate
• Moxisylyte
• Nabumetone
• Naproxen
• Nateglinide
• Nepafenac
• Niflumic Acid
• Nimesulide
• Nimesulide Beta Cyclodextrin
• Oxaprozin
• Oxyphenbutazone
• Parecoxib
• Phenoxybenzamine
• Phentolamine
• Phenylbutazone
• Piketoprofen
• Pioglitazone
• Piroxicam
• Pramlintide
• Pranoprofen
• Prazosin
• Proglumetacin
• Propyphenazone
• Proquazone
• Repaglinide
• Rofecoxib
• Rosiglitazone
• Salicylic Acid
• Salsalate
• Saxagliptin
• Sitagliptin
• Sodium Salicylate
• St John's Wort
• Sulindac
• Tamsulosin
• Tenoxicam
• Terazosin
• Tiaprofenic Acid
• Tolazamide
• Tolbutamide
• Tolfenamic Acid
• Tolmetin
• Trimazosin
• Urapidil
• Valdecoxib
• Vildagliptin