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This document provides vital safety and warning information regarding the use of Maxzide (triamterene / hydrochlorothiazide). It is important to review the following points and discuss any concerns with your healthcare provider.

• Increased Potassium Levels: Maxzide may elevate potassium levels in your body, which can lead to severe heart issues. Individuals with kidney problems, diabetes, or those taking other potassium-increasing medications are at heightened risk. Regular blood tests will be necessary to monitor potassium levels. Alert your doctor if you experience symptoms such as nausea, muscle weakness, or fatigue.

• Fluid and Electrolyte Imbalance: This medication can disrupt fluid and electrolyte balance, potentially causing dizziness, weakness, or a rapid heartbeat. Those with kidney, liver, or heart conditions, or those on higher doses, should be particularly cautious.

• Acidosis Risk: Rarely, Maxzide can cause a buildup of acid in the body, which can become life-threatening. This is more likely in cases of severe illness. Inform medical staff you are on Maxzide if hospitalized. Seek medical attention if you experience fatigue or confusion.

• Liver Coma Risk: In rare cases, individuals with severe liver conditions may experience hepatic coma. Symptoms include confusion, drowsiness, and tremors. Immediate medical consultation is necessary if these occur.

• Allergic Reactions: Those with a history of sulfa allergies are at risk for severe allergic reactions, such as rashes or difficulty breathing. Inform your healthcare provider of any known medication allergies.

• Gout Risk: Maxzide may increase uric acid levels, potentially triggering gout. Individuals with a history of gout or kidney issues should be cautious and report joint pain or swelling to their doctor.

• Increased Blood Sugar: The medication might raise blood sugar levels, particularly in diabetic patients. Regular monitoring and potential medication adjustments may be required.

• Vision Problems: Maxzide can cause eye pain or vision changes, which could result in permanent blindness if untreated. Stop the medication and contact your healthcare provider immediately if you experience these symptoms.

Contraindications include inability to urinate, existing kidney issues, high potassium levels, or if you are taking other potassium-increasing drugs. Consult your healthcare provider if any of these conditions apply to ensure safe use of Maxzide.

When taking this medication, you may experience some common side effects as your body adjusts. These include dizziness, lightheadedness, headaches, and an upset stomach. To minimize dizziness and lightheadedness, try rising slowly from sitting or lying positions. While these side effects are typically mild, it's important to inform your healthcare provider if they persist or worsen.

Some people may also notice muscle cramps, dry mouth, blurred vision, nausea, vomiting, diarrhea, or orthostatic hypotension, which is low blood pressure when standing up. Although these are usually not severe, if they become bothersome, reach out to your healthcare provider for guidance.

More serious side effects, though rare, require immediate medical attention. These include symptoms of dehydration or electrolyte imbalance, such as unusual dry mouth, excessive thirst, muscle cramps or weakness, irregular heartbeat, or confusion. Furthermore, be vigilant for signs of kidney problems like changes in urine output, decreased vision, or eye pain.

If you experience a severe allergic reaction, characterized by a rash, itching, swelling, severe dizziness, or difficulty breathing, seek urgent medical care. Other serious reactions include dangerously high potassium levels, which may cause a racing heart, chest pain, nausea, or weakness, and high levels of acid in the blood, leading to confusion or a fast heartbeat.

While these side effects cover many possibilities, always contact your healthcare provider if you notice any other unusual effects.