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When taking this medication, you might experience mild side effects such as nausea, vomiting, diarrhea, or stomach pain. These can often be minimized by taking the medication after meals. If these symptoms persist or worsen, it is important to consult a healthcare provider. Occasionally, you may notice an empty tablet shell in your stool; this is harmless as your body has already absorbed the medication.

Serious side effects, although less common, require immediate medical attention. These include severe stomach or intestinal issues like bleeding, blockage, or puncture. Symptoms to watch for are abdominal swelling, black or bloody stools, constipation, dizziness, a rapid heartbeat, severe stomach pain, difficulty swallowing, severe vomiting, or vomit that resembles coffee grounds.

Another serious concern is the potential for high potassium levels in the blood, known as hyperkalemia. Symptoms can include muscle cramps, weakness, severe dizziness, a slow or irregular heartbeat, changes in mental state such as confusion or restlessness, tingling in the hands or feet, or unusually cold skin.

While rare, a severe allergic reaction is also possible. Seek urgent medical care if you experience a rash, itching or swelling (particularly of the face, tongue, or throat), severe dizziness, or difficulty breathing. This summary does not encompass all possible side effects. If you experience any effects not mentioned here, reach out to your healthcare provider for guidance.

Certain medications can interact with this drug, potentially affecting how it works or increasing the risk of side effects. These include:

• Antacids containing aluminum.
• Aspirin and other salicylates, like salsalate.
• Blood pressure medications, such as ACE inhibitors (e.g., lisinopril) and angiotensin blockers (e.g., losartan).
• Drospirenone.
• Medicines that slow down the movement of food or drugs through the digestive system, including anticholinergics (e.g., belladonna, scopolamine, benztropine), antispasmodics (e.g., glycopyrrolate, oxybutynin), and strong opioids (e.g., morphine).
• Eplerenone.
• Certain heart medications, like quinidine and digoxin.
• Lithium.
• Potassium supplements, including salt substitutes.
• Pramlintide.
• Potassium-sparing diuretics, such as amiloride, spironolactone, and triamterene.

If your doctor has advised you to take low-dose aspirin (81-162 mg per day) to prevent heart attack or stroke, continue as directed unless advised otherwise by your healthcare provider. For more information, consult your doctor or pharmacist.