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When using this medication, it is important to be aware of potential interactions and precautions to ensure safe and effective use. Below are key safety considerations:

• Drug Interactions:

  • Avoid using skin-applied antihistamines, such as diphenhydramine cream, ointment, or spray, as they may interact with this medication.
  • Taking MAO inhibitors (e.g., isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) with this drug can lead to serious, potentially fatal interactions. Most MAO inhibitors should not be used during or within two weeks before starting this medication. Consult your doctor on when to start or stop these medications.
  • Inform your doctor or pharmacist if you are using other products that cause drowsiness, including opioid pain or cough relievers (e.g., codeine, hydrocodone), alcohol, marijuana, sleep or anxiety drugs (e.g., alprazolam, lorazepam, zolpidem), muscle relaxants (e.g., carisoprodol, cyclobenzaprine), or other antihistamines (e.g., cetirizine, diphenhydramine).

• Product Labels and Ingredients:

  • Check the labels of all your medications, including allergy or cough-and-cold products, as they may contain ingredients that cause drowsiness. Consult your pharmacist for guidance on using these products safely.

• Interference with Medical Tests:

  • This medication may affect certain medical or laboratory tests, such as brain scans for Parkinson’s disease, urine drug screenings, and allergy skin tests, potentially leading to false results. Ensure that all healthcare providers and lab personnel are aware that you are taking this medication.

By adhering to these guidelines and consulting with healthcare professionals, you can minimize risks and ensure safe usage of the medication.

Certain products could interact with this medication, including skin-applied antihistamines like diphenhydramine cream, ointment, or spray. Taking this medication with MAO inhibitors can lead to a severe, potentially life-threatening reaction. You should avoid using MAO inhibitors (such as isocarboxazid, linezolid, Metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, Rasagiline, safinamide, Selegiline, Tranylcypromine) while on this medication. It is also recommended to not take most MAO inhibitors for two weeks before starting this treatment. Consult your doctor for guidance on when to begin or cease taking this medicine.

Inform your doctor or pharmacist if you're using other products that cause drowsiness, including opioid pain or cough medications (like codeine or Hydrocodone), alcohol, cannabis, sleep or anxiety medications (such as Alprazolam, Lorazepam, or Zolpidem), muscle relaxants (such as Carisoprodol or Cyclobenzaprine), or additional antihistamines (like Cetirizine or diphenhydramine). Always check the labels on all your medications, such as those for allergies or cough-and-cold, since they may contain ingredients that cause drowsiness. Ask your pharmacist how to use these products safely.

This medication may affect certain medical or lab tests, like brain scans for Parkinson's disease, urine drug screenings, or allergy skin tests, possibly resulting in inaccurate results. Ensure that all your healthcare providers and lab personnel are aware that you are using this medication.