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When considering the use of cough-and-cold medications in children, it is important to follow specific safety guidelines:

• Cough-and-cold products have not been proven safe or effective for children under 6 years old. Only use these products in this age group if instructed by a doctor.
• Certain products, including some long-acting tablets or capsules, are not suitable for children under 12 years old.
• Do not use these medications to induce sleep in children.
• For children under 2 years of age, these products are not recommended due to the risk of serious, potentially fatal, slow or shallow breathing.
• For children aged 2 years and older, adhere strictly to the doctor's instructions, ensuring the lowest effective dose is administered. Avoid exceeding the prescribed frequency.
• Before administering any other cough-and-cold medications, consult with a doctor or pharmacist to avoid duplicating active ingredients that may impair breathing.
• In the event of unusual slow or shallow breathing, seek immediate medical attention.

These precautions help ensure the safe use of cough-and-cold medications in children.

You might experience mild side effects such as drowsiness, dizziness, headache, upset stomach, nausea, constipation, or dry mouth. These are generally not a cause for concern, but if they persist or worsen, consult your healthcare provider.

There are some more serious side effects to be aware of. Contact your doctor immediately if you experience mental or mood changes, such as confusion or hallucinations, ringing in the ears, tremors, difficulty urinating, vision changes, easy bruising or bleeding, or uncontrolled movements.

In rare cases, this medication can cause very serious side effects. Seek immediate medical attention if you have slow or shallow breathing, seizures, or symptoms of neuroleptic malignant syndrome (NMS), which include fever, muscle stiffness, severe tiredness, confusion, sweating, irregular heartbeat, dark urine, or signs of kidney problems.

Though extremely rare, severe allergic reactions can occur. Get emergency help if you notice symptoms such as rash, itching or swelling (especially of the face, tongue, or throat), severe dizziness, or trouble breathing.

This overview does not cover all possible side effects. If you experience any other unusual symptoms, reach out to your healthcare provider for guidance.

Certain products can interact with this medication. These include skin-applied antihistamines like diphenhydramine cream, ointment, or spray, as well as cabergoline, metoclopramide, and pergolide. Additionally, using MAO inhibitors with this drug can lead to a severe, potentially life-threatening interaction. You should not use MAO inhibitors, such as isocarboxazid, linezolid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, or tranylcypromine, during or within two weeks prior to starting treatment with this medication. Consult your doctor about when to begin or discontinue use.

Moreover, this medication can heighten the risk of significant side effects, including slow or shallow breathing and severe drowsiness or dizziness, if used with other products that cause drowsiness or breathing issues. Inform your doctor or pharmacist if you are taking any other medications that may have these effects, such as opioid pain relievers (like codeine or hydrocodone), alcohol, marijuana (cannabis), sleep or anxiety medications (such as alprazolam, lorazepam, or zolpidem), muscle relaxants (like carisoprodol or cyclobenzaprine), or other antihistamines (such as cetirizine or diphenhydramine).

Always check the labels on your medications, including those for allergies or cough and cold, as they may contain ingredients that cause drowsiness. Consult your pharmacist to ensure safe use of these products.

Lastly, this medication may affect certain laboratory tests, including some pregnancy, blood sugar, and allergy skin tests, potentially leading to inaccurate results. Inform lab personnel and all your healthcare providers that you are using this medication.