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Celontin (methsuximide) is a medication used to treat absence seizures. It is important to be aware of the following safety information and precautions while using this medication. Should you have any concerns, please consult your healthcare provider.

• Low Blood Cell Counts: This medication may cause low blood cell counts, which is rare but can be serious. Low white blood cell counts may weaken your immune system, increasing your risk of infections. Regular blood tests will be conducted by your provider to monitor this. Contact your healthcare provider immediately if you experience frequent illnesses such as sore throats or fevers.

• Liver and Kidney Damage: Celontin (methsuximide) has the potential to cause damage to the liver or kidneys. Regular monitoring of liver and kidney function will be performed. Inform your provider if you have a history of liver or kidney issues before starting this medication.

• Lupus: In rare instances, this medication can trigger lupus, an autoimmune condition. Symptoms may include fatigue, fever, joint pain, and rashes. Discuss any concerns with your healthcare provider.

• Suicidal Thoughts or Behavior: There is an increased risk of suicidal thoughts or actions when taking antiepileptic drugs like Celontin. Be vigilant for new or worsening depression, or any unusual changes in mood or behavior, particularly during the initial months of treatment or following dosage adjustments. Report any alarming changes to your healthcare provider. Seek immediate medical help if experiencing thoughts of self-harm.

• Seizures from Sudden Discontinuation: Do not abruptly stop taking Celontin without consulting your healthcare provider, as this can lead to seizures due to withdrawal.

• Treatment Specificity: Celontin is effective only for absence seizures and may exacerbate other seizure types if used alone. If you experience mixed seizure types, additional medications may be necessary. Discuss suitable treatment options with your provider.

Please ensure you discuss any existing health conditions and medications with your healthcare provider to avoid potential interactions or complications.

When taking this medication, some common side effects may occur, although they are generally mild. These include drowsiness, dizziness, nausea, vomiting, diarrhea, stomach pain, constipation, loss of appetite, weight loss, and headaches. You might also experience blurred vision or difficulty with coordination and movement. If any of these side effects persist or worsen, it’s advisable to consult your healthcare provider for further guidance.

There are other side effects that some individuals may report, such as irritability, nervousness, sensitivity to light, hiccups, difficulty sleeping, confusion, mood instability, and difficulty thinking quickly. In some cases, users might experience depression, hives, rash, or swelling around the eyes. While these are less common, it is important to monitor how you feel and consult your healthcare provider if you experience any concerning symptoms.

Serious side effects, though rare, warrant immediate medical attention. These include signs of low blood cell counts, such as increased frequency of illness, unusual fatigue, or shortness of breath. Additionally, watch out for signs of a serious allergic reaction, such as a rash, itching, swelling (particularly of the face, tongue, or throat), severe dizziness, or trouble breathing. If you notice any of these severe symptoms, seek urgent medical care. Always keep an open line of communication with your healthcare provider regarding any new or worsening symptoms.